TIGAR与NOX调控线粒体自噬和ROS在神经退行性疾病发病机制中的作用

81671252
2016
H0912.神经退行性变及相关疾病
王燕
面上项目
教授
苏州大学
57万元
NOX;线粒体自噬;ROS;神经退行性疾病;TIGAR
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 DRAM1 deficiency affects the organization and function of the Golgi apparatus 期刊论文 Wei Mingzhen;Zhu Zhou;Wu Junchao;Wang Yan;Geng Ji;Qin Zheng Hong
2 Autophagy: Biology And Diseases, Chapter 25 Autophagy and Ubiquitin-Proteasome System 专著 Yan Wang;Weidong Le
3 Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy 期刊论文 Wu Zhihao;Wang Yan;Lim Junghyun;Liu Boxiang;Li Yanping;Vartak Rasika;Stankiewicz Trisha;Montgomery Stephen;Lu Bingwei
4 Mechanisms and roles of mitophagy in neurodegenerative diseases 期刊论文 Wang Yan;Liu Na;Lu Bingwei
5 Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-alpha 期刊论文 Feng Wei;Wang Yan;Liu Zi-Qi;Zhang Xuan;Han Rong;Miao You-Zhu;Qin Zheng-Hong
6 DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway 期刊论文 Lu Ting;Zhu Zhou;Wu Junchao;She Hua;Han Rong;Xu Haidong;Qin Zheng Hong
7 TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury 期刊论文 Zhang Ding-Mei;Zhang Tian;Wang Ming-Ming;Wang Xin-Xin;Qin Yuan-Yuan;Wu Junchao;Han Rong;Sheng Rui;Wang Yan;Chen Zhong;Han Feng;Ding Yuqiang;Li Mei;Qin Zheng-Hong
8 NADPH protects against kainic acid-induced excitotoxicity via autophagy-lysosome pathway in rat striatum and primary cortical neurons 期刊论文 Zi-Qi Liu;Na Liu;Si-Si Huang;Miao-Miao Lin;Shu Qin;Jun-Chao Wu;Zhong-Qin Liang;Zheng-Hong Qin;Yan Wang
9 Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms 期刊论文 Zhao Yifan;Shen Xiao;Zhu Ying;Wang Anqi;Xiong Yajie;Wang Long;Fei Yao;Wang Yan;Wang Wenjuan;Lin Fang;Liang Zhongqin
10 Olanzapine induced autophagy through suppression of NF-kappa B activation in human glioma cells 期刊论文 Zhu Ying;Zhao Yi Fan;Liu Rui Si;Xiong Ya Jie;Shen Xiao;Wang Yan;Liang Zhong Qin
11 Reduced Nicotinamide Adenine Dinucleotide Phosphate Inhibits MPTP-Induced Neuroinflammation and Neurotoxicity 期刊论文 Ying Zhou;Junchao Wu;Rui Sheng;Mei Li;Yan Wang;Rong Han;Feng Han;Zhong Chen;Zheng Hong Qin
12 DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR 期刊论文 Geng Ji;Zhang Rong;Yuan Xiao;Xu Haidong;Zhu Zhou;Wang Xinxin;Wang Yan;Xu Guoqiang;Guo Wenjie;Wu Junchao;Qin Zheng-Hong
13 Cathepsin L induced PC-12 cell apoptosis via activation of B-Myb and regulation of cell cycle proteins 期刊论文 Shen Xiao;Zhao Yi fan;Xu Shu qing;Wang Long;Cao Hui min;Cao Ying;Zhu Ying;Wang Yan;Liang Zhong qin
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