间充质干细胞与免疫微环境的交互调控在肝硬化中的作用及机制
81530043
2015
H11.医学免疫学
时玉舫
重点项目
教授
苏州大学
274万元
间充质干细胞;炎症;肝硬化;细胞治疗;免疫调控
2016-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases | 期刊论文 | Shi Yufang;Wang Yu;Li Qing;Liu Keli;Hou Jianquan;Shao Changshun;Wang Ying |
| 2 | Fibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development | 期刊论文 | Gong Zheng;Shang Bingxue;Chu Yunpeng;Chen Xiaodong;Li Qing;Liu Keli;Chen Yongjing;Huang Yin;Hang Yanyan;Shang Qianwen;Zheng Zhiyuan;Song Lin;Li Yanan;Liu Rui;Xu Chenchang;Zhang Xiaoren;Liu Baochi;Wang Luowei;Shao Changshun;Wang Ying;Shi Yufang |
| 3 | COVID-19 infection: the China and Italy perspectives. | 期刊论文 | Jun Chen;Hongzhou Lu;Gerry Melino;Stefania Boccia;Mauro Piacentini;Walter Ricciardi;Ying Wang;Yufang Shi;Tongyu Zhu |
| 4 | 一种治疗糖尿病的干细胞药物 | 专利 | 时玉舫;曹丽娟;房建凯;陈永井;王莹 |
| 5 | Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases? | 期刊论文 | Alexei Verkhratsky;Qing Li;Sonia Melino;Gerry Melino;Yufang Shi |
| 6 | Skeletal muscle stem cells confer maturing macrophages anti-inflammatory properties through insulin-like growth factor-2 | 期刊论文 | Fang Jiankai;Zhang Shengchao;Liu Zhanhong;Pan Yongsha;Cao Lijuan;Hou Pengbo;Chen Yongjing;Zhang Yuyan;Li Xiaolei;Liu Rui;Shang Qianwen;Zheng Zhiyuan;Song Lin;Li Yanan;Fu Zhonglin;Lin Liangyu;Melino Gerry;Wang Ying;Shao Changshun;Shi Yufang |
| 7 | The tango of ROS and p53 in tissue stem cells | 期刊论文 | Chen Youguo;Liu Keli;Shi Yufang;Shao Changshun |
| 8 | HSD11B1 is upregulated synergistically by IFN gamma and TNF alpha and mediates TSG-6 expression in human UC-MSCs | 期刊论文 | Huang Peiqing;Li Yinghong;Xu Chenchang;Melino Gerry;Shao Changshun;Shi Yufang |
| 9 | COVID-19 infection: the perspectives on immune responses | 期刊论文 | Shi Yufang;Wang Ying;Shao Changshun;Huang Jianan;Gan Jianhe;Huang Xiaoping;Bucci Enrico;Piacentini Mauro;Ippolito Giuseppe;Melino Gerry |
| 10 | Tumour cell-derived exosomes endow mesenchymal stromal cells with tumour-promotion capabilities. | 期刊论文 | Liangyu Lin;Lming Du;Kai Cao;Yin Huang;Pengpei Yu;Liying Zhang;Fengying Li;Ying Wang;Yufang Shi |
| 11 | 肌肉干细胞在制备抗炎药物中的应用 | 专利 | 时玉舫;房建凯;陈永井;刘展红;张胜超 |
| 12 | TNFalpha-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2+ neutrophils. | 期刊论文 | Yu P F;Huang Y;Han Y Y;Lin L Y;Sun W H;Rabson A B;Wang Y;Shi Y F |
| 13 | Harnessing tumor-associated macrophages as aids for cancer immunotherapy. | 期刊论文 | Xiaolei Li;Rui Liu;Xiao Su;Yongsha Pan;Xiaofeng Han;Changshun Shao;Yufang Shi |
| 14 | 一种诱导造血干细胞向T系细胞分化的方法和试剂盒 | 专利 | 时玉舫;龚拯;陈永井 |
| 15 | Single cell transcriptomic analysis of human mesenchymal stem cells reveals limited heterogeneity | 期刊论文 | Huang Yin;Li Qing;Zhang Kunshan;Hu Mingyuan;Wang Yu;Du Liming;Lin Liangyu;Li Siguang;Sorokin Lydia;Melino Gerry;Shi Yufang;Wang Ying |
| 16 | Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets | 期刊论文 | Shi Yufang;Du Liming;Lin Liangyu;Wang Ying |
| 17 | Downregulation of CXCL12 in mesenchymal stromal cells by TGFbeta promotes breast cancer metastasis. | 期刊论文 | Yu P F;Huang Y;Xu C L;Lin L Y;Han Y Y;Sun W H;Hu G H;Rabson A B;Wang Y;Shi Y F |
| 18 | IFNr and TNFa synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide | 期刊论文 | Li Xiaolei;Shang Bingxue;Li Ya nan;Shi Yufang;Shao Changshun |
| 19 | Asynchronous actions of immune responses in COVID-19 patients. | 期刊论文 | Yufang Shi;Guoqiang Zhou;Qing Li |
| 20 | SHP1 Regulates Bone Mass by Directing Mesenchymal Stem Cell Differentiation | 期刊论文 | Jiang Menghui;Zheng Chunxing;Shou Peishun;Li Na;Cao Gang;Chen Qing;Xu Chunliang;Du Liming;Yang Qian;Cao Jianchang;Han Yanyan;Li Fengying;Cao Wei;Liu Feng;Rabson Arnold B.;Roberts Arthur I.;Xie Weifen;Wang Ying;Shi Yufang |
| 21 | Mesenchymal stromal cells pretreated with pro-inflammatory cytokines promote skin wound healing throughVEGFC-mediated angiogenesis | 期刊论文 | Zhu Mengting;Chu Yunpeng;Shang Qianwen;Zheng Zhiyuan;Li Yanan;Cao Lijuan;Chen Yongjing;Cao Jianchang;Lee Oscar K.;Wang Ying;Melino Gerry;Lv Guozhong;Shao Changshun;Shi Yufang |
| 22 | CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages | 期刊论文 | Chunxing Zheng;Qian Yang;Chunliang Xu;Peishun Shou;Jianchang Cao;Menghui Jiang;Qing Chen;Gang Cao;Yanyan Han;Fengying Li;Wei Cao;Liying Zhang;Li Zhang;Yufang Shi;Ying Wang |
| 23 | Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy. | 期刊论文 | Rui Liu;Xiaolei Li;Hui Ma;Qian Yang;Qianwen Shang;Lin Song;Zhiyuan Zheng;Shengchao Zhang;Yongsha Pan;Peiqing Huang;Jiankai Fang;Yanan Li;Zhanhong Liu;Lijuan Cao;Chao Feng;Zheng Gong;Yongjing Chen;Ying Wang;Gerry Melino;Changshun Shao;Yufang Shi |
| 24 | Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells. | 期刊论文 | Zhiyuan Zheng;Shanfen Jia;Changshun Shao;Yufang Shi |
| 25 | Kynurenic acid, an IDO metabolite, controls TSG-6-mediated immunosuppression of human mesenchymal stem cells. | 期刊论文 | Guan Wang;Kai Cao;Keli Liu;Yueqing Xue;Arthur I. Roberts;Fengying Li;Arnold B. Rabson;Ying Wang;Yufang Shi |
| 26 | 调节干细胞的免疫调节作用的方法 | 专利 | 时玉舫;任广文;张莉英 |
| 27 | Macrophages inhibit adipogenic differentiation of adipose tissue derived mesenchymal stem/stromal cells by producing pro-inflammatory cytokines | 期刊论文 | Ma Hui;Li Ya-nan;Song Lin;Liu Rui;Li Xiaolei;Shang Qianwen;Wang Ying;Shao Changshun;Shi Yufang |
| 28 | Local proliferation initiates macrophage accumulation in adipose tissue during obesity | 期刊论文 | Zheng C.;Yang Q.;Cao J.;Xie N.;Liu K.;Shou P.;Qian F.;Wang Y.;Shi Y. |
| 29 | Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea | 期刊论文 | Shang Qianwen;Chu Yunpeng;Li Yanan;Han Yuyi;Yu Daojiang;Liu Rui;Zheng Zhiyuan;Song Lin;Fang Jiankai;Li Xiaolei;Cao Lijuan;Gong Zheng;Zhang Liying;Chen Yongjing;Wang Ying;Shao Changshun;Shi Yufang |
| 30 | Spermidine alleviates experimental autoimmune encephalomyelitis through inducing inhibitory macrophages | 期刊论文 | Yang Q.;Zheng C.;Cao J.;Cao G.;Shou P.;Lin L.;Velletri T.;Jiang M.;Chen Q.;Han Y.;Li F.;Wang Y.;Cao W.;Shi Y. |
| 31 | Fate decision of mesenchymal stem cells: adipocytes or osteoblasts | 期刊论文 | Q Chen;P Shou;C Zheng;M Jiang;G Cao;Q Yang;J Cao;N Xie;T Velletri;X Zhang;C Xu;L Zhang;H Yang;J Hou;Y Wang;Y Shi |
| 32 | Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II | 期刊论文 | Liu Keli;Lin Liangyu;Li Qing;Xue Yueqing;Zheng Fanjun;Wang Guan;Zheng Chunxing;Du Liming;Hu Mingyuan;Huang Yin;Shao Changshun;Kong Xiangyin;Melino Gerry;Shi Yufang;Wang Ying |
| 33 | IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation- dependent Anti-inflammatory Properties. | 期刊论文 | Du Liming;Lin Liangyu;Li Qing;Liu Keli;Huang Yin;Wang Xuefeng;Cao Kai;Chen Xiaodong;Cao Wei;Li Fengying;Shao Changshun;Wang Ying;Shi Yufang |
| 34 | Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals | 期刊论文 | Jiang Menghui;Ye Jiayin;Wang Xuefeng;Li Na;Wang Ying;Shi Yufang |
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