稀有人参皂苷Rk3诱导雌激素受体阳性乳腺癌细胞凋亡的抗肿瘤作用机制研究

21808184
2018
B0810.农业与食品化工
傅容湛
青年科学基金项目
副教授
西北大学
28万元
抗癌作用;代谢调控;量效关系;人参皂苷;天然药物工程
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer 期刊论文 Xuqian Den;Jiaqi Zhao;Linlin Qu;Zhiguang Duan;Rongzhan Fu;Chenhui Zhu;Daidi Fan
2 Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway 期刊论文 Mi Tian;Pei Ma;Yan Zhang;Yu Mi;Daidi Fan
3 The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway 期刊论文 Huanhuan Liu;Jiaqi Zhao;Rongzhan Fu;Chenhui Zhu;Daidi Fan
4 Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer 期刊论文 Yannan Liu;Daidi Fan
5 Protopanaxatriol-type saponin protects against acetaminophen-induced liver injury through ROS-mediated JNK pathway 期刊论文 Linlin Qu;Rongzhan Fu;Xiaoxuan Ma;Daidi Fan
6 Ginsenoside Rk1 induces cell death through ROS-mediated PTEN/PI3K/Akt/ mTOR signaling pathway in MCF-7 cells 期刊论文 Yinan Hong;Daidi Fan
7 Structural characterization and immunomodulatory activity of a polysaccharide from Eurotium cristatum 期刊论文 Haohan Li;Yu Mi;Zhiguang Duan;Pei Ma;Daidi Fan
8 Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma 期刊论文 Manling Hu;Jing Yang;Linlin Qu;Xuqian Deng;Zhiguang Duan;Rongzhan Fu;Lihua Liang;Daidi Fan
9 Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice 期刊论文 Xue Bai;Rongzhan Fu;Zhiguang Duan;Pan Wang;Chenhui Zhu;Daidi Fan
10 Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy 期刊论文 Linlin Qu;Rongzhan Fu;Xiaoxuan Ma;Daidi Fan
11 人参皂苷的定向生物转化研究进展 期刊论文 赵婧;王盼;刘彦楠;傅容湛;段志广;范代娣
12 Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition 期刊论文 Xue Bai;Rongzhan Fu;Zhiguang Duan;Yannan Liu;Chenhui Zhu;Daidi Fan
13 Ginsenoside CK Inhibits Hypoxia-Induced Epithelial–Mesenchymal Transformation through the HIF-1/NF-B Feedback Pathway in Hepatocellular Carcinoma 期刊论文 Jingjing Zhang;Xiaoxuan Ma;Daidi Fan
14 Study on the hypnotic effect of rare protopanaxadiol-type and protopanaxatriol-type ginsenosides 期刊论文 Ning Mou;Zhiguang Duan;Pei Ma;Rongzhan Fu;Daidi Fan
15 Human-like collagen promotes the healing of acetic acid-induced gastric ulcers in rats by regulating NOS and growth factors 期刊论文 Mimi Xing;Rongzhan Fu;Yannan Liu;Pan Wang;Pei Ma;Chenhui Zhu;Daidi Fan
16 Ginsenoside Rk1 inhibits cell proliferation and promotes apoptosis in lung squamous cell carcinoma by calcium signaling pathway 期刊论文 Xining An;Rongzhan Fu;Pei Ma;Xiaoxuan Ma;Daidi Fan
17 Folic acid-modified ginsenoside Rg5-loaded bovine serum albumin nanoparticles for targeted cancer therapy in vitro and in vivo 期刊论文 Yanan Dong;Rongzhan Fu;Jing Yang;Pei Ma;Lihua Liang;Yu Mi;Daidi Fan
18 Ginsenoside Rk3 Suppresses Hepatocellular Carcinoma Development through Targeting the Gut-Liver Axis 期刊论文 Linlin Qu;Xiaoxuan Ma;Daidi Fan
19 Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells 期刊论文 Yinan Hong;Daidi Fan
20 Inhibitory Effect of pH-Responsive Nanogel Encapsulating Ginsenoside CK against Lung Cancer 期刊论文 Ziyang Xue;Rongzhan Fu;Zhiguang Duan;Lei Chi;Chenhui Zhu;Daidi Fan
21 Anti-Photoaging and Anti-Inflammatory Effects of Ginsenoside Rk3 During Exposure to UV Irradiation 期刊论文 Shichao Wan;Yannan Liu;Jingjing Shi;Daidi Fan;Binglin Li
22 The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K 期刊论文 Yannan Liu;Daidi Fan
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