肠道粘膜屏障在溃疡性结肠炎发病机制方面的研究
81470825
2014
H0302.消化系统免疫相关疾病
夏利军
面上项目
教授
苏州大学
75万元
溃疡性结肠炎;粘蛋白;粘蛋白型O型糖;肠道粘膜屏障;肠道菌群
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Plasma soluble podoplanin is a novel marker for the diagnosis of tumor occurrence and metastasis | 期刊论文 | Zhao X;Pan Y;Ren W;Shen F;Xu M;Yu M;Fu J;Xia L;Ruan C;Zhao Y |
| 2 | Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney | 期刊论文 | Song K;Fu J;Song J;Herzog BH;Bergstrom K;Kondo Y;McDaniel JM;McGee S;Silasi-Mansat R;Lupu F;Chen H;Bagavant H;Xia L |
| 3 | Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice. | 期刊论文 | Bergstrom K;Fu J;Johansson M E V;Liu X;Gao N;Wu Q;Song J;McDaniel J M;McGee S;Chen W;Braun J;Hansson G C;Xia L |
| 4 | Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis | 期刊论文 | Yi J;Bergstrom K;Fu J;Shan X;McDaniel JM;McGee S;Qu D;Houchen CW;Liu X;Xia L |
| 5 | Loss of core 1-derived O-glycans decreases breast cancer development in mice | 期刊论文 | Song K;Herzog BH;Fu J;Sheng M;Bergstrom K;McDaniel JM;Kondo Y;McGee S;Cai X;Li P;Chen H;Xia L |
| 6 | Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis. | 期刊论文 | Perez-Munoz Maria Elisa;Bergstrom Kirk;Peng Vincent;Schmaltz Robert;Jimenez-Cardona Roberto;Marsteller Nathan;McGee Sam;Clavel Thomas;Ley Ruth;Fu Jianxin;Xia Lijun;Peterson Daniel A |
| 7 | Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets | 期刊论文 | Pan Yanfang;Yago Tadayuki;Fu Jianxin;Herzog Brett;McDaniel J Michael;Mehta-D&39;Souza Padmaja;Cai Xiaofeng;Ruan Changgeng;McEver Rodger P;West Christopher;Dai Kesheng;Chen Hong;Xia Lijun |
| 8 | Epsin is required for disheveled stability and Wnt signaling activation in colon cancer development | 期刊论文 | Chang B;Tessneer KL;McManus J;Liu X;Hahn S;Pasula S;Wu H;Song H;Chen Y;Cai X;Dong Y;Brophy ML;Rahrna R;Ma JX;Xia L;Chen H |
| 9 | Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells | 期刊论文 | Li Yun;Fu Jianxin;Ling Yun;Yago Tadayuki;McDaniel J. Michael;Song Jianhua;Bai Xia;Kondo Yuji;Qin Yannan;Hoover Christopher;McGee Samuel;Shao Bojing;Liu Zhenghui;Sonon Roberto;Azadi Parastoo;Marth Jamey D.;McEver Rodger P.;Ruan Changgeng;Xia Lijun |
| 10 | Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice. | 期刊论文 | Bergstrom Kirk;Liu Xiaowei;Zhao Yiming;Gao Nan;Wu Qian;Song Kai;Cui Yi;Li Yun;McDaniel J Michael;McGee Samuel;Chen Weichang;Huycke Mark M;Houchen Courtney W;Zenewicz Lauren A;West Christopher M;Chen Hong;Braun Jonathan;Fu Jianxin;Xia Lijun |
| 11 | Loss of intestinal O-glycans promotes spontaneous duodenal tumors. | 期刊论文 | Gao Nan;Bergstrom Kirk;Fu Jianxin;Xie Biao;Chen Weichang;Xia Lijun |
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