Wnt/β-catenin信号通路在钛颗粒诱导成骨细胞性骨形成减少中的作用及机制
81372018
2013
H0611.运动系统疾病研究新技术与新方法
耿德春
面上项目
研究员
苏州大学
70万元
Wnt/β-catenin;无菌性松动;成骨细胞;关节置换;磨损颗粒
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model | 期刊论文 | Shao Hongguo;Shen Ji;Wang Mingjun;Cui Jingfu;Wang Yijun;Zhu Shijun;Zhang Wen;Yang Huilin;Xu Yaozeng;Geng Dechun |
| 2 | Inhibitory effects of melatonin on titanium particle-induced inflammatory bone resorption and osteoclastogenesis via suppression of NF-kappa B signaling | 期刊论文 | Ping Zichuan;Wang Zhirong;Shi Jiawei;Wang Liangliang;Guo Xiaobin;Zhou Wei;Hu Xuanyang;Wu Xiexing;Liu Yu;Zhang Wen;Yang Huilin;Xu Yaozeng;Gu Ye;Geng Dechun |
| 3 | Pharmaceutical inhibition of glycogen synthetase kinase 3 beta suppresses wear debris-induced osteolysis | 期刊论文 | Geng Dechun;Wu Jian;Shao Hongguo;Zhu Shijun;Wang Yijun;Zhang Wen;Ping Zichuan;Hu Xuanyang;Zhu Xuesong;Xu Yaozeng;Yang Huilin |
| 4 | Strontium ranelate inhibits titanium-particle-induced osteolysis, by restraining inflammatory osteoclastogenesis in vivo | 期刊论文 | Liu Xing;Zhu Shijun;Cui Jingfu;Shao Hongguo;Zhang Wen;Yang Huilin;Xu Yaozeng;Geng Dechun;Yu Long |
| 5 | Inhibitory effect of icariin on Ti-induced inflammatory osteoclastogenesis | 期刊论文 | Cui Jingfu;Zhu Mo;Zhu Shijun;Wang Guixian;Xu Yaozeng;Geng Dechun |
| 6 | Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3 beta/beta-catenin signal pathway | 期刊论文 | Gu Ye;Wang Zhirong;Shi Jiawei;Wang Liangliang;Hou Zhenyang;Guo Xiaobin;Tao Yunxia;Wu Xiexing;Zhou Wei;Liu Yu;Zhang Wen;Xu Yaozeng;Yang Huilin;Xue Feng;Geng Dechun |
| 7 | 锶离子对钛颗粒诱导破骨细胞活化的作用 | 期刊论文 | 朱世军;徐耀增;崔京福;邵洪国;朱锋;耿德春 |
| 8 | 氯化锂在治疗假体周围骨溶解药物中的用途 | 专利 | 耿德春;杨惠林;徐耀增;朱雪松;陶云霞 |
| 9 | Downregulation of miR-106b attenuates inflammatory responses and joint damage in collagen-induced arthritis | 期刊论文 | Tao Yunxia;Wang Zhirong;Wang Liangliang;Shi Jiawei;Guo Xiaobin;Zhou Wei;Wu Xiexing;Liu Yu;Zhang Wen;Yang Huilin;Shi Qin;Xu Yaozeng;Geng Dechun |
| 10 | 淫羊藿苷活化β-连环蛋白信号通路促进钛颗粒诱导的小鼠骨髓基质干细胞成骨分化 | 期刊论文 | 陶云霞;胡宣洋;平子川;王骏骅;王亮亮;史佳伟;吴勰星;郭晓斌;徐耀增;杨惠林;耿德春 |
| 11 | 淫羊藿苷抑制钛颗粒诱导的炎症反应 | 期刊论文 | 崔京福;徐耀增;朱世军;朱锋;付稳;邵洪国;耿德春 |
| 12 | Icariin attenuates titanium-particle inhibition of bone formation by activating the Wnt/beta-catenin signaling pathway in vivo and in vitro | 期刊论文 | Wang Junhua;Tao Yunxia;Ping Zichuan;Zhang Wen;Hu Xuanyang;Wang Yijun;Wang Liangliang;Shi Jiawei;Wu Xiexing;Yang Huilin;Xu Yaozeng;Geng Dechun |
| 13 | 锶离子对钛颗粒诱导破骨细胞活化的作用 | 期刊论文 | 朱世军;徐耀增;崔京福;邵洪国;朱锋;耿德春 |
| 14 | Strontium inhibits titanium particle-induced osteoclast activation and chronic inflammation via suppression of NF-kappa B pathway | 期刊论文 | Zhu Shijun;Hu Xuanyang;Tao Yunxia;Ping Zichuan;Wang Liangliang;Shi Jiawei;Wu Xiexing;Zhang Wen;Yang Huilin;Nie Zhikui;Xu Yaozeng;Wang Zhirong;Geng Dechun |
| 15 | Theaflavin-3,3 '-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway | 期刊论文 | Hu Xuanyang;Ping Zichuan;Gan Minfeng;Tao Yunxia;Wang Liangliang;Shi Jiawei;Wu Xiexing;Zhang Wen;Yang Huilin;Xu Yaozeng;Wang Zhirong;Geng Dechun |
| 16 | 雷尼酸锶对钛颗粒诱导炎性骨溶解的抑制作用 | 期刊论文 | 朱世军;徐耀增;崔京福;邵洪国;朱锋;耿德春 |
| 17 | Intervertebral disc degeneration induced by intradiscal poly(methyl methacrylate) leakage after spine augmentation in an in vivo rabbit model | 期刊论文 | Mao Haiqing;Geng Dechun;Zhu Xuesong;Ji Shundong;Zhu Mo;Gao Maofeng;Zou Jun;Yang Huilin |
| 18 | Melatonin attenuates titanium particle-induced osteolysis via activation of Wnt/beta-catenin signaling pathway | 期刊论文 | Ping Zichuan;Hu Xuanyang;Wang Liangliang;Shi Jiawei;Tao Yunxia;Wu Xiexing;Hou Zhenyang;Guo Xiaobin;Zhang Wen;Yang Huilin;Xu Yaozeng;Wang Zhirong;Geng Dechun |
| 19 | Inhibition of titanium-particle-induced inflammatory osteolysis after local administration of dopamine and suppression of osteoclastogenesis via D2-like receptor signaling pathway | 期刊论文 | Yang Huilin;Xu Yaozeng;Zhu Mo;Gu Ye;Zhang Wen;Shao Hongguo;Wang Yijun;Ping Zichuan;Hu Xuanyang;Wang Liangliang;Geng Dechun |
| 20 | Lithium chloride inhibits titanium particle-induced osteoclastogenesis by inhibiting the NF-kappa B pathway | 期刊论文 | Hu Xuanyang;Wang Zhirong;Shi Jiawei;Guo Xiaobin;Wang Liangliang;Ping Zichuan;Tao Yunxia;Yang Huilin;Zhou Jun;Xu Yaozeng;Geng Dechun |
| 21 | 淫羊藿苷对钛颗粒诱导的炎症性骨溶解的抑制作用 | 期刊论文 | 邵洪国;崔京福;朱世军;王熠军;朱锋;杨惠林;耿德春;徐耀增 |
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