ADAM12的水解功能在小细胞肺癌增殖和转移中的分子机制研究

31470772
2014
C0505.蛋白质、多肽与酶生物化学
许国强
面上项目
教授
苏州大学
85万元
小细胞肺癌;定量蛋白质组学;端基标记;去整合素金属蛋白酶ADAM12;增殖和转移
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1 期刊论文 Yang Zhang;Chunyan Duan;Jing Yang;Suping Chen;Qing Liu;Liang Zhou;Zhengyun Huang;Ying Xu;Guoqiang Xu
2 Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition 期刊论文 Yaobin Liu;Xian He;Yiyan Sui;Rong Yu;Guoqiang Xu
3 Protein C-terminal enzymatic labeling identifies novelcaspase cleavages during the apoptosis of multiple myeloma cells induced bykinase inhibition 期刊论文 Wenwen Duan;Suping Chen;Yang Zhang;Dan Li;Rong Wang;Shi Chen;Junbei Li;Xiaoyan Qiu;Guoqiang Xu
4 Proteomic and biochemical analyses reveal a novel mechanism for promoting protein ubiquitination and degradation by UFBP1, a key component of ufmylation 期刊论文 Ying Zhu;Qing Lei;Dan Li;Yang Zhang;Xiaogang Jiang;Zhanhong Hu;Guoqiang Xu
5 Ubiquitin ligase TRAF2 attenuates the transcriptional activity of the core clock protein BMAL1 and affects the maximal Per1 mRNA level of the circadian clock in cells 期刊论文 Suping Chen;Jing Yang;Lu Yang;Yang Zhang;Liang Zhou;Qing Liu;Chunyan Duan;Crystal A. Mieres;Guanghai Zhou;Guoqiang Xu
6 ProC-TEL: Profiling of protein C-termini by enzymatic labeling 期刊论文 Wenwen Duan;Guoqiang Xu
7 Optimization and application of protein C-terminal labeling by carboxypeptidase Y (羧肽酶Y标记蛋白质羧基端方法的优化及应用) 期刊论文 段文文;张阳;许国强
8 PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant 期刊论文 Jia Li;Chengbing Wang;Chuanqing Wu;Cao Ting;Xu Guoqiang;Meng Qing;Wang Baolin
9 Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells 期刊论文 Yanqing Zhou;Lipeng Xiong;Yang Zhang;Rong Yu;Xiaogang Jiang;Guoqiang Xu
10 Quantitative proteomics and biochemical analyses reveal the role of endoplasmin in the regulation of the expression and secretion of A Disintegrin And Metalloproteinase 12 期刊论文 Lipeng Xiong;Wenwen Yan;Emmanuel Zubiab;Yanqing Zhou;Yang Zhang;Qianqian Duan;Mahesh Narayan;Guoqiang Xu
11 Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse 期刊论文 Chengbing Wang;Jia Li;Ken-Ichi Takemaru;Xiaogang Jiang;Guoqiang Xu;Baolin Wang
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