来那度胺治疗多发性骨髓瘤的分子机制研究

31270874
2012
C0505.蛋白质、多肽与酶生物化学
许国强
面上项目
教授
苏州大学
80万元
来那度胺;定量蛋白质组学;多发性骨髓瘤;泛素化;高效液相色谱质谱联用仪
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Profiling lysine ubiquitination by selective enrichment of ubiquitin remnant-containing peptides. 期刊论文 Xu, Guoqiang|Deglincerti, Alessia|Paige, Jeremy S|Jaffrey, Samie R|
2 Comprehensive Profiling of Protein Ubiquitination for Drug Discovery 期刊论文 Xu, Guoqiang|Jaffrey, Samie R.|
3 Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK 期刊论文 Nuriel, Tal|Gross, Steven S.|Xu, Guoqiang|Glatt, Charles E.|
4 Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition 期刊论文 He, Xian|Sui, Yiyan|Yu, Rong|Xu, Guoqiang|
5 Enzymatic and pharmacological regulation of histone ubiquitination and deubiquitination 期刊论文 Wenwen Duan|Qian Li|Guoqiang Xu|
6 Coupled local translation and degradation regulate growth cone collapse 期刊论文 Colak, Dilek|Hengst, Ulrich|Xu, Guoqiang|Jaffrey, Samie R.|
7 A lysine-to-arginine mutation on NEDD8 markedly reduces the activity of cullin RING E3 ligase through the impairment of neddylation cascades 期刊论文 #Sui, Yiyan|#Liu, Yaobin|Xu, Guoqiang|
8 Site-Specific Acetyl Lysine Antibodies Reveal Differential Regulation of Histone Acetylation upon Kinase Inhibition 期刊论文 Shi Chen|Suping Chen|Qianqian Duan|Guoqiang Xu|
9 定量蛋白质组学研究发现UFM1修饰连接酶UFL1的潜在功能 期刊论文 朱莹|蒋小岗|
10 A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition 期刊论文 Xu, Guoqiang|Jiang, Xiaogang|Jaffrey, Samie R|
11 A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function 期刊论文 Jiang, Xiaogang|Chen-Kiang, Selina|Jaffrey, Samie R.|Xu, Guoqiang|
12 Proteomic identification of protein ubiquitination events 专著 Xu, Guoqiang|Jaffrey, Samie R.|
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