前列腺癌相关生物模块和通路的数据库构建及其功能分析

31170795
2011
C0504.物理生物学
沈百荣
面上项目
教授
苏州大学
60万元
系统生物学数据库;前列腺癌;生物模块和通路;生物功能分析
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The Topology and Dynamics of Protein Complexes: Insights from Intra-Molecular Network Theory 期刊论文 Zhou, Jianhong|Yan, Wenying|Chen, Jiajia|Shen, Bairong|
2 Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression 期刊论文 Chen, Luonan|Chen, Luonan|Shen, Bairong|Shen, Bairong|
3 The construction of an amino acid network for understanding protein structure and function 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
4 The construction of an amino acid network for understanding protein structure and function 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
5 Key regulators in prostate cancer identified by co-expression module analysis. 期刊论文 Zhao Z|Zhao Z|Shen B.|Shen B.|
6 Deciphering oncogenic drivers: from single genes to integrated pathways 期刊论文 M. Sun|M. Sun|B. Shen|B. Shen|
7 Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis 期刊论文 Guo, Lingchuan|Guo, Lingchuan|Shen, Bairong|Shen, Bairong|
8 3 Evaluation and Comparison of Multiple Aligners for Next-Generation Sequencing Data Analysis 期刊论文 Zhang, Wenyu|Zhang, Wenyu|Shen, Bairong|Shen, Bairong|
9 Identifying novel glioma associated pathways based on systems biology level meta-analysis 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
10 Molecular Signature of Cancer at Gene Level or Pathway Level? Case Studies of Colorectal Cancer and Prostate Cancer Microarray Data 期刊论文 Shen, Bairong|Shen, Bairong|Zhang, Daqing|Zhang, Daqing|
11 Biomedical text mining and its applications in cancer research 期刊论文 Vongsangnak, Wanwipa|Vongsangnak, Wanwipa|Shen, Bairong|Shen, Bairong|
12 Amino Acid Network for the Discrimination of Native Protein Structures from Decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
13 Amino Acid Network for the Discrimination of Native Protein Structures from Decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
14 Key regulators in prostate cancer identified by co-expression module analysis. 期刊论文 Zhao Z|Zhao Z|Shen B.|Shen B.|
15 Biomedical text mining and its applications in cancer research 期刊论文 Vongsangnak, Wanwipa|Vongsangnak, Wanwipa|Shen, Bairong|Shen, Bairong|
16 Identification and Functional Annotation of Genome-Wide ER-Regulated Genes in Breast Cancer Based on ChIP-Seq Data 期刊论文 Shen, Bairong|Shen, Bairong|Xu, Zhonghua|Xu, Zhonghua|
17 Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer 期刊论文 Kaipia, Antti|Kaipia, Antti|Shen, Bairong|Shen, Bairong|
18 Combined SVM-CRFs for Biological Named Entity Recognition with Maximal Bidirectional Squeezing 期刊论文 Zhu, Fei|Shen, Bairong|
19 Discovery and characterization of long intergenic non-coding RNAs (lincRNA) module biomarkers in prostate cancer: an integrative analysis of RNA-Seq data 期刊论文 Z. Zhao|Z. Zhao|B. Shen|B. Shen|
20 SVR_CAF: An integrated score function for detecting native protein structures among decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
21 Top associated SNPs in prostate cancer are significantly enriched in cis-expression quantitative trait loci and at transcription factor binding sites. 期刊论文 Shen B|Shen B|Zhao Z.|Zhao Z.|
22 MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model 期刊论文 Shaoyan Hu|Shaoyan Hu|Bairong Shen|Bairong Shen|
23 Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network 期刊论文 D. Yang|D. Yang|B. Shen|B. Shen|
24 Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis 期刊论文 Guo, Lingchuan|Guo, Lingchuan|Shen, Bairong|Shen, Bairong|
25 Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer 期刊论文 Kaipia, Antti|Kaipia, Antti|Shen, Bairong|Shen, Bairong|
26 Post genome-wide association studies functional characterization of prostate cancer risk loci 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
27 3 Evaluation and Comparison of Multiple Aligners for Next-Generation Sequencing Data Analysis 期刊论文 Zhang, Wenyu|Zhang, Wenyu|Shen, Bairong|Shen, Bairong|
28 Understanding Amino Acid Mutations in Hepatitis B Virus Proteins for Rational Design of Vaccines and Drugs 期刊论文 Z. Jiang|Z. Jiang|B. Shen|B. Shen|
29 Segmentation of Neuronal Structures Using SARSA (lambda)-Based Boundary Amendment with Reinforced Gradient-Descent Curve Shape Fitting 期刊论文 Fu, Yuchen|Fu, Yuchen|Shen, Bairong|Shen, Bairong|
30 Post genome-wide association studies functional characterization of prostate cancer risk loci 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
31 Translational Bioinformatics for Diagnostic and Prognostic Prediction of Prostate Cancer in the Next-Generation Sequencing Era 期刊论文 Yang, Dongrong|Yang, Dongrong|Shen, Bairong|Shen, Bairong|
32 SVR_CAF: An integrated score function for detecting native protein structures among decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
33 Segmentation of Neuronal Structures Using SARSA (lambda)-Based Boundary Amendment with Reinforced Gradient-Descent Curve Shape Fitting 期刊论文 Fu, Yuchen|Fu, Yuchen|Shen, Bairong|Shen, Bairong|
34 Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression 期刊论文 Chen, Luonan|Chen, Luonan|Shen, Bairong|Shen, Bairong|
35 Identifying novel glioma associated pathways based on systems biology level meta-analysis 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
36 Structure-based prediction of the effects of a missense variant on protein stability 期刊论文 Chen, Biao|Tan, Ge|Vihinen, Mauno|Shen, Bairong|
37 Amino Acid Network for the Discrimination of Native Protein Structures from Decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
38 Understanding Amino Acid Mutations in Hepatitis B Virus Proteins for Rational Design of Vaccines and Drugs 期刊论文 Z. Jiang|Z. Jiang|B. Shen|B. Shen|
39 A Systems Biology Perspective on Rational Design of Peptide Vaccine Against Virus Infections 期刊论文 Chen, Jiajia|Wang, Ying|Guo, Deyin|Shen, Bairong|
40 Translational Biomedical Informatics in the Cloud: Present and Future 期刊论文 Yan, Wenying|Yan, Wenying|Shen, Bairong|Shen, Bairong|
41 Molecular Dynamic Simulation to Explore the Molecular Basis of Btk-PH Domain Interaction with Ins(1,3,4,5)P4 期刊论文 Sun, Maomin|Luo, Cheng|Shen, Bairong|Hu, Guang|
42 Identification and Functional Annotation of Genome-Wide ER-Regulated Genes in Breast Cancer Based on ChIP-Seq Data 期刊论文 Shen, Bairong|Shen, Bairong|Xu, Zhonghua|Xu, Zhonghua|
43 Translational Bioinformatics for Diagnostic and Prognostic Prediction of Prostate Cancer in the Next-Generation Sequencing Era 期刊论文 Yang, Dongrong|Yang, Dongrong|Shen, Bairong|Shen, Bairong|
44 Discovery and characterization of long intergenic non-coding RNAs (lincRNA) module biomarkers in prostate cancer: an integrative analysis of RNA-Seq data 期刊论文 Z. Zhao|Z. Zhao|B. Shen|B. Shen|
45 Translational Biomedical Informatics in the Cloud: Present and Future 期刊论文 Yan, Wenying|Yan, Wenying|Shen, Bairong|Shen, Bairong|
46 Top associated SNPs in prostate cancer are significantly enriched in cis-expression quantitative trait loci and at transcription factor binding sites. 期刊论文 Shen B|Shen B|Zhao Z.|Zhao Z.|
47 New genes drive the evolution of gene interaction networks in the human and mouse genomes 期刊论文 B. Shen|B. Shen|M. Long|M. Long|
48 Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer 期刊论文 Kaipia, Antti|Kaipia, Antti|Shen, Bairong|Shen, Bairong|
49 Deciphering oncogenic drivers: from single genes to integrated pathways 期刊论文 M. Sun|M. Sun|B. Shen|B. Shen|
50 Amino acid contact energy networks impact protein structure and evolution 期刊论文 Chen, Biao|Chen, Biao|Shen, Bairong|Shen, Bairong|
51 Amino Acid Network for the Discrimination of Native Protein Structures from Decoys 期刊论文 Hu, Guang|Hu, Guang|Shen, Bairong|Shen, Bairong|
52 Molecular Signature of Cancer at Gene Level or Pathway Level? Case Studies of Colorectal Cancer and Prostate Cancer Microarray Data 期刊论文 Shen, Bairong|Shen, Bairong|Zhang, Daqing|Zhang, Daqing|
53 Amino acid contact energy networks impact protein structure and evolution 期刊论文 Chen, Biao|Chen, Biao|Shen, Bairong|Shen, Bairong|
54 Performance comparison and evaluation of software tools for microRNA deep-sequencing data analysis 期刊论文 Liu, Feng|Vongsangnak, Wanwipa|Jing, Qing|Shen, Bairong|
55 Identification of novel microRNA regulatory pathways associated with heterogeneous prostate cancer 期刊论文 Kaipia, Antti|Kaipia, Antti|Shen, Bairong|Shen, Bairong|
56 Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network 期刊论文 D. Yang|D. Yang|B. Shen|B. Shen|
57 Identification of candidate miRNA biomarkers from miRNA regulatory network with application to prostate cancer 期刊论文 Guo, Feng|Guo, Feng|Shen, Bairong|Shen, Bairong|
58 Identification of candidate miRNA biomarkers from miRNA regulatory network with application to prostate cancer 期刊论文 Guo, Feng|Guo, Feng|Shen, Bairong|Shen, Bairong|
59 New genes drive the evolution of gene interaction networks in the human and mouse genomes 期刊论文 B. Shen|B. Shen|M. Long|M. Long|
60 MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model 期刊论文 Shaoyan Hu|Shaoyan Hu|Bairong Shen|Bairong Shen|
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