自噬参与神经兴奋性毒性的机制及药物干预

30772560
2007
H3501.神经精神药物药理
秦正红
面上项目
教授
苏州大学
30万元
神经退行性疾病.;自噬;兴奋性毒性
2008-01-01到2010-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid 期刊论文 Wu, Jun-Chao|Liang, Zhong-Qin|Zhang, Xing-Ding|Wang, Yan|Han, Rong|Qin, Zheng-Hong|Gu, Zhen-Lun|
2 Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases 期刊论文 Qin, Zheng-hong|Wang, Yan|Dong, Xiao-xia|
3 Down-Regulation of Bcl-2 Enhances Autophagy Activation and Cell Death Induced by Mitochondrial Dysfunction in Rat Striatum 期刊论文 Han, Feng|Qin, Zheng-Hong|Wang, Ye|Han, Rong|Fukunaga, Kohji|Wu, Jun-Chao|Zhang, Xing-Ding|Lin, Fang|
4 p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum 期刊论文 Zhang, Xing-Ding|Zhang, Xuan|Fukunaga, Kohji|Wu, Jun-Chao|Liang, Zhong-Qin|Han, Feng|Gu, Zhen-Lun|Han, Rong|Wang, Yan|Qin, Zheng-Hong|Wang, Ye|
5 Molecular and cellular mechanisms of excitotoxic neuronal death 期刊论文 Qin, Zheng-hong|Wang, Yan|
6 p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms 期刊论文 Wu, Jun-Chao|Gu, Zhen-Lun|Han, Rong|Qin, Zhen-Hong|Wang, Yan|Liang, Zhong-Qin|Cao, Yi|Dong, Xiao-Xia|
7 Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia 期刊论文 Qin, Ai-Ping|Qin, Zheng-Hong|Liu, Jianqing|Qin, Yuan-Yuan|Yang, Lei|Zhang, Hui-Ling|Hong, Li-Zhi|Xu, Min|Liu, Chun-Feng|
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