基于肺癌精准靶向治疗的基因影像组学研究
81872510
2018
H1824.肿瘤大数据与人工智能
钟文昭
面上项目
主任医师
南方医科大学
57万元
影像组学;生物信息学;肺腺癌;异质性;基因组学
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Toward an Expert Level of Lung Cancer Detection and Classification Using a Deep Convolutional Neural Network | 期刊论文 | Chao Zhang;Xing Sun;Kang Dang;Ke Li;Xiao-wei Guo;Jia Chang;Zong-qiao Yu;Fei-yue Huang;Yun-sheng Wu;Zhu Liang;Zai-yi Liu;Xue-gong Zhang;Xing-lin Gao;Shao-hong Huang;Jie Qin;Wei-neng Feng;Tao Zhou;Yan-bin Zhang;Wei-jun Fang;Ming-fang Zhao;Xue-ning Yang;Qing Zhou;Yi-long Wu;Wen-zhao Zhong |
| 2 | Multiomics analysis reveals a distinct response mechanism in multiple primary lung adenocarcinoma after neoadjuvant immunotherapy | 期刊论文 | Zhang Chao;Yin Kai;Liu Si-Yang;Yan Li-Xu;Su Jian;Wu Yi-Long;Zhang Xu-Chao;Zhong Wen-Zhao;Yang Xue-Ning |
| 3 | Recursive partitioning analysis of patients with oligometastatic non-small cell lung cancer: a retrospective study | 期刊论文 | Jia-Tao Zhang;Si-Yang Liu;Hong-Hong Yan;Yi-Long Wu;Qiang Nie;Wen-Zhao Zhong |
| 4 | Three‐dimensional printed navigational template for localizing small pulmonary nodules: A case‐controlled study | 期刊论文 | Rui Fu;Yun-Fei Chai;Jia-Tao Zhang;Tao Zhang;Xiao-Kun Chen;Song Dong;Hong-Hong Yan;Xue-Ning Yang;Mei-Ping Huang;Yi-Long Wu;Jian Zhuang;Wen-Zhao Zhong |
| 5 | Wait-and-See Treatment Strategy Could be Considered for Lung Adenocarcinoma with Special Pleural Dissemination Lesions, and Low Genomic Instability Correlates with Better Survival | 期刊论文 | Ying Chen;Wen-Fang Tang;Huan Lin;Hua Bao;Wei Li;Ao Wang;Xue Wu;Jian Su;Jie-Shan Lin;Yang W.Shao;Xue-Ning Yang;Yi-Long Wu;Wen-Zhao Zhong |
| 6 | ITHscore: comprehensive quantification of intra-tumor heterogeneity in NSCLC by multi-scale radiomic features | 期刊论文 | Jiaqi Li;Zhenbin Qiu;Chao Zhang;Sijie Chen;Mengmin Wang;Qiuchen Meng;Haiming Lu;Lei Wei;Hairong Lv;Wenzhao Zhong;Xuegong Zhang |
| 7 | Disparity in clinical outcomes between pure and combined pulmonary large-cell neuroendocrine carcinoma: a multi-center retrospective study | 期刊论文 | Jia-Tao Zhang;Ye Li;Li-Xu Yan;Zheng-Fei Zhu;Xiao-Rong Dong;Qian Chu;Lin Wu;Hong-Mei Zhang;Chun-Wei Xu;Gen Lin;Zong-Yang Yu;Jie Hu;Bo Zhu;Hui-Juan Wang;Fan Yang;Zheng-Bo Song;Zheng-Bo Han;Meng-Xia Li;Jie Lin;Yi-Long Wu;Jin-Liang Wang;Wen-Zhao Zhong |
| 8 | A New Prognostic Index Combines the Metabolic Response and RECIST 1.1 to Evaluate the Therapeutic Response in Patients With Non-Small Cell Lung Cancer | 期刊论文 | Wen-Fang Tang;Qingyi Hou;Jun-Tao Lin;Dongjiang Li;Jie-Shan Lin;Jinghua Chen;Zhen-Bin Qiu;Xiang-Peng Chu;Xiongwen Yang;Hong-Hong Yan;Shuxia Wang;Yi-Long Wu;Wen-Zhao Zhong |
| 9 | A Novel Radiopathological Grading System to Tailor Recurrence Risk for Pathologic Stage IA Lung Adenocarcinoma | 期刊论文 | Zhen-Bin Qiu;Meng-Min Wang;Jin-Hai Yan;Chao Zhang;Yi-Long Wu;Sheng Zhang;Wen-Zhao Zhong |
| 10 | Neoadjuvant immunotherapy in Non-Small Cell Lung Cancer:State of the art | 期刊论文 | Kang Jin;Zhang Chao;Zhong Wen-Zhao |
| 11 | Metal-marked mixed reality technology for pulmonary nodule localization | 期刊论文 | Jia-Tao Zhang;Tao Zhang;Zhao-Wen Qiu;Wen-Zhao Zhong |
| 12 | Genomic signatures define three subtypes of EGFR-mutant stage II–III non-small-cell lung cancer with distinct adjuvant therapy outcomes | 期刊论文 | Si-Yang Liu;Hua Bao;Qun Wang;Weimin Mao;Yedan Chen;Xiaoling Tong;Song-Tao Xu;Lin Wu;Yucheng Wei;Yongyu Liu;Chun Chen;Ying Cheng;Rong Yin;Fan Yang;Shengxiang Ren;Xiaofei Li;Jian Li;Cheng Huang;Zhidong Liu;Shun Xu;Ke-Neng Chen;Shidong Xu;Lei Liu;Ping Yu;Bu-Hai Wang;Haitao Ma;Hong-Hong Yan;Song Dong;Xu-Chao Zhang;Jian Su;Jin-Ji Yang;Xue-Ning Yang;Qing Zhou;Xue Wu;Yang Shao;Wen-Zhao Zhong;Yi-Long Wu |
| 13 | Real-world Scenario of Patients with Lung Cancer Amid the COVID-19 Pandemic in China | 期刊论文 | Rui Fu;Lin Wu;Chao Zhang;Qian Chu;Jie Hu;Gen Lin;Lin Yang;Ji-Sheng Li;Xue-Ning Yang;Jin-Ji Yang;Qing Zhou;Yi-Long Wu;Wen-Zhao Zhong |
| 14 | Plasma extracellular vesicle microRNAs for pulmonary ground-glass nodules | 期刊论文 | Jia-Tao Zhang;Hao Qin;Fiona Ka Man Cheung;Jian Su;Da-Dong Zhang;Shi-Yi Liu;Xiao-Fang Li;Jing Qin;Jun-Tao Lin;Ben-Yuan Jiang;Song Dong;Ri-Qiang Liao;Nie Qiang;Xue-Ning Yang;Hai-Yan Tu;Qing Zhou;Jin-Ji Yang;Xu-Chao Zhang;Ya-Nan Zhang;Yi-Long Wu;Wen-Zhao Zhong |
| 15 | Timing and origins of local and distant metastases in lung cancer. | 期刊论文 | Wen-Fang Tang;Min Wu;Hua Bao;Yang Xu;Jie-Shan Lin;Yi Liang;Yu Zhang;Jian Su;Jia-Tao Zhang;Fang-Ping Xu;Jing-Hua Chen;Rui Fu;Ying Chen;Tao Yang;Qing-Ke Chen;Ting-Ting Wu;Xue Wu;Yang Shao;Jian-Tao Zheng;Zhi Xie;Zhi-Yi Lv;Song Dong;Yi-Long Wu;Wen-Zhao Zhong |
| 16 | Drainage tube hole suture improvement: Removal‐free stitches | 期刊论文 | Rui Fu;Jia‐Tao Zhang;Song Dong;Ying Chen;Chao Zhang;Wen‐Fang Tang;Jin Xia;Qiang Nie;Wen‐Zhao Zhong |
| 17 | Identification of heritable rare variants associated with early-stage lung adenocarcinoma risk | 期刊论文 | Rui Fu;Jia-Tao Zhang;Rong-Rong Chen;Hong Li;Zai-Xian Tai;Hao-Xiang Lin;Jian Su;Xiang-Peng Chu;Chao Zhang;Zhen-Bin Qiu;Zi-Hao Chen;Wen-Fang Tang;Song Dong;Xue-Ning Yang;Guo-Qing Zhang;Guo-Ping Zhao;Yi-Long Wu;Wen-Zhao Zhong |
| 18 | Feasibility and Safety of Neoadjuvant Alectinib in a Patient With ALK-Positive Locally Advanced NSCLC | 期刊论文 | Chao Zhang;Li-Xu Yan;Ben-Yuan Jiang;Yi-Long Wu;Wen-Zhao Zhong |
| 19 | ASO Author Reflections: Lung Adenocarcinoma with Accidental Invisible Pleural Dissemination Lesions: Wait-and-See Strategy for Tumors with Indolent Biologic Characteristics | 期刊论文 | Wen-Fang Tang;Wen-Zhao Zhong |
| 20 | Genomic characteristics and drug screening among organoids derived from non‐small cell lung cancer patients | 期刊论文 | Jing-Hua Chen;Xiang-Peng Chu;Wen-Zhao Zhong;Qiang Nie;Wen-Fang Tang;Jian Su;Hong-Hong Yan;Hongping Zheng;Ze-Xin Chen;Xin Chen;Mengmeng Song;Xin Yi;Pansong Li;Yan-Fang Guan;Gang Li;Chu-Xia Deng;Rafael Rosell;Yi-Long Wu;Wen-Zhao Zhong |
| 21 | Dynamic 18 F-FDG PET/CT can predict the major pathological response to neoadjuvant immunotherapy in non-small cell lung cancer. | 期刊论文 | Zhi-Yong Chen;Rui Fu;Xiao-Yue Tan;Li-Xu Yan;Wen-Fang Tang;Zhen-Bin Qiu;Yi-Fan Qi;Yu-Fa Li;Qing-Yi Hou;Yi-Long Wu;Wen-Zhao Zhong;Ben-Yuan Jiang |
| 22 | Randomized Trial of an Improved Drainage Strategy vs Routine Chest Tube after Lung Wedge Resection | 期刊论文 | Jia-Tao Zhang;Song Dong;Xiang-Peng Chu;Shao-Min Lin;Run-Ying Yu;Ben-Yuan Jiang;Ri-Qiang Liao;Qiang Nie;Hong-Hong Yan;Xue-Ning Yang;Yi-Long Wu;Wen-Zhao Zhong |
| 23 | Emerging therapies for non-small cell lung cancer | 期刊论文 | Chao Zhang;Natasha B.Leighl;Yi-Long Wu;Wen-Zhao Zhong |
| 24 | Quantifying invasiveness of clinical stage IA lung adenocarcinoma with computed tomography texture features | 期刊论文 | Zhen-Bin Qiu;Chao Zhang;Xiang-Peng Chu;Fei-Yue Cai;Xue-Ning Yang;Yi-Long Wu;Wen-Zhao Zhong |
| 25 | The regularity of anatomical variations of dominant pulmonary segments in the right upper lobe | 期刊论文 | Zi‐Hao Chen;Xiang‐Peng Chu;Jia‐Tao Zhang;Rui Fu;Jin Kang;Jing‐Hua Chen;Ben‐Yuan Jiang;Yi‐Long Wu;Wen‐Zhao Zhong;Qiang Nie |
| 26 | A three-dimensional printing navigational template combined with mixed reality technique for localizing pulmonary nodules | 期刊论文 | Fu Rui;Zhang Chao;Zhang Tao;Chu Xiang-Peng;Tang Wen-Fang;Yang Xue-Ning;Huang Mei-Ping;Zhuang Jian;Wu Yi-Long;Zhong Wen-Zhao |
| 27 | Genomic Landscape and Immune Microenvironment Features of Preinvasive and Early Invasive Lung Adenocarcinoma | 期刊论文 | Chao Zhang;Jianjun Zhang;Fang-Ping Xu;Yin-Guang Wang;Zhi Xie;Jian Su;Song Dong;Qiang Nie;Yang Shao;Qing Zhou;Jin-Ji Yang;Xue-Ning Yang;Xu-Chao Zhang;Zhi Li;Yi-Long Wu;Wen-Zhao Zhong |
| 28 | Induction immune-checkpoint inhibitors for resectable oncogene-mutant NSCLC: A multicenter pooled analysis | 期刊论文 | Chao Zhang;Hua-Fei Chen;Shi Yan;Lin Wu;Li-Xu Yan;Xiao-Long Yan;Dong-Sheng Yue;Chun-Wei Xu;Min Zheng;Ji-Sheng Li;Si-Yang Liu;Ling-Ling Yang;Ben-Yuan Jiang;Qiu-Xiang Ou;Zhen-Bin Qiu;Yang Shao;Yi-Long Wu;Wen-Zhao Zhong |
| 29 | Precise resection of multiple pulmonary nodules using a three‐dimensional reconstruction model: A case report | 期刊论文 | Xiang‐Peng Chu;Zi‐Hao Chen;Shao‐Min Lin;Wen‐Fang Tang;Jia‐Tao Zhang;Yao‐Ming Lai;Rui Fu;Zhen‐Bin Qiu;Jun‐Tao Lin;Qiang Nie;Xue‐Ning Yang;Yi‐Long Wu;Wen‐Zhao Zhong |
| 30 | Watershed analysis of the target pulmonary artery for real-time localization of non-palpable pulmonary nodules | 期刊论文 | Xiang-Peng Chu;Zi-Hao Chen;Shao-Min Lin;Jia-Tao Zhang;Zhao-Wen Qiu;Wen-Fang Tang;Rui Fu;Zhen-Bin Qiu;Xue-Ning Yang;Yi-Long Wu;Qiang Nie;Wen-Zhao Zhong |
| 31 | Sublobectomy for stage IA1 ‐2 invasive lung adenocarcinoma with consolidation tumor ratio ≤ 0.25 | 期刊论文 | Yi‐Fan Qi;Zhen‐Bin Qiu;Chao Zhang;Rui Fu;Xiong‐Wen Yang;Xiang‐Peng Chu;Zi‐Hao Chen;Xue‐Ning Yang;Yi‐Long Wu;Wen‐Zhao Zhong |
| 32 | 一种基于流域分析技术的肺叶自动分段方法 | 专利 | 钟文昭;褚祥鹏;邱兆文 |
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