绿脓杆菌 (P. aeruginosa) 影响呼吸道上皮细胞层功能的机制研究

81570001
2015
H0102.呼吸系统感染、炎症与免疫
陈正豪
面上项目
教授
浙江师范大学
55万元
上皮细胞;绿脓杆菌;通透性;肺炎;囊性纤维化
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 ERK and AMPK Signaling Pathways Involve in Apical Solution-Induced Downregulation of Ion Transport in Cultured Pig Tracheal Epithelia 会议论文 Weiyi Xu;Winnie Ngan Fung Li;Jeng-Haur Chen
2 CFTR Founder Mutation Causes Protein Trafficking Defects In Chinese Patients With Cystic Fibrosis. 期刊论文 Leung GKC;Ying D;Mak CCY;Chen XY;Xu W;Yeung KS;Wong WL;Chu YWY;Mok GTK;Chau CSK;McLuskey J;Ong WP;Leong HY;Chan KYK;Yang W;Chen JH;Li AM;Sham PC;Lau YL;Chung B;Lee SL
3 Bacterial killing of cultured pig tracheal epithelia was not altered by HCO3−-free medium 会议论文 Zhu S.;Chen J.H.
4 The processing defect of ΔF508- and ΔY512-CFTR are generated by similar mechanisms with different initial flaws 会议论文 Xinying Chen;Siyu Zhu;Molly Pik Fan Wong;Jeng-Haur Chen
5 Regional Disturbances Around the F508 Residues Exhibited Various Impacts on The function of The Cystic Fibrosis Transmembrane Conductance Regulator. 会议论文 Chen X.Y.;Zhu S.;Xu W.;Chen J.H.
6 Effects of the apical Krebs solution on ion transport of cultured pig tracheal epithelia 会议论文 Xu W.;Li W.N.F.;Chen J.H.
7 A defective flexible loop contributes to the processing and gating defects of the predominant cystic fibrosis-causing mutation 期刊论文 Chen Xinying;Zhu Siyu;Zhenin Michael;Xu Weiyi;Bose Samuel J;Wong Molly Pik Fan;Leung George P H;Senderowitz Hanoch;Chen Jeng Haur
8 Exploring Bacterial Killing Mechanisms on The Apical Surface of Cultured Pig Tracheal Epithelia 会议论文 Siyu Zhu;Jeng-Haur Chen
9 Altering intracellular pH reveals the kinetic basis of intraburst gating in the CFTR Cl- channel. 期刊论文 Chen J.H.;Xu W.;Sheppard D.N.
10 The N505 residue is important for maintaining normal protein processing of the cystic fibrosis transmembrane conductance regulator 会议论文 Chen X.Y.;Wong M.P.F.;Chen J.H.
11 Sodium in the apical solution mediates downregulation of ion transport in cultured pig tracheal epithelia 会议论文 Weyi Xu;Winnie Ngan Fung Li;Jeng-Haur Chen
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