基于自噬相关PI3K/Akt/mTOR信号通路探索五味子总木脂素降肝脂作用及作用机制

81803793
2018
H3211.中药内分泌与代谢药理
张翼
青年科学基金项目
副教授
北京中医药大学
21万元
脂肪肝;自噬;PI3K/Akt/mTOR信号通路;肝脂;五味子总木脂素
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Schisandrae Fructus oil-induced elevation in serum triglyceride and lipoprotein concentrations associated with physiologic hepatomegaly in mice 期刊论文 Si-Yuan Pan;Xue-Lan Song;Zhao-Heng Lin;Qing Yu;Yi Zhang;Hai-Chuan Tai;Gan Luo;Xiao- Yan Wang;Pei-Li Zhu;Nan Sun;Zhu-Sheng Chu;Zhi-Ling Yu;Yi Zhang;Kam-Ming Ko
2 Schisandra Chinensis Lignans Suppresses the Production of Inflammatory Mediators Regulated by NF-kappaB, AP-1, and IRF3 in Lipopolysaccharide-Stimulated RAW264.7 Cells. 期刊论文 Gan Luo;Brian Chi-Yan Cheng;Hui Zhao;Xiu-Qiong Fu;Ran Xie;Shuo-Feng Zhang;Si-Yuan Pan;Yi Zhang
3 Tibetan Medicine for Diabetes Mellitus: Over view of Pharmacological Perspectives 期刊论文 Li-Shan Yan;Brian Chi-Yan Cheng;Shuo-Feng Zhang;Gan Luo;Chao Zhang;Qing-Gao Wang;Xiu-Qiong Fu;Yi-Wei Wang;Yi Zhang
4 Evaluation of beneficial and adverse effects of a diet supplemented with Schisandrae Fructus seed ethanol extract on lipid and glucose metabolism in normal and hypercholesterolemic/hyperglycemic mice 期刊论文 Xiao-Yan Wang;Xue-Lan Song;Yi Zhang;Gan Luo;Hai-Chuan Tai;Zhao-Heng Lin;Pei-Li Zhu;Nan Sun;Zhu-Sheng Chu;Zhi-Ling Yu;Si-Yuan Pan;Jin-Fa Tang;Kam-Ming Ko
5 Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3 beta/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes 期刊论文 Yi Zhang;Li Shan Yan;Yu Ding;Brian Chi Yan Cheng;Gan Luo;Jing Kong;Tong Hua Liu;Shuo Feng Zhang
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