整合素β1与细胞外基质蛋白相互作用调控间充质干细胞向神经管畸形组织定向迁移的作用机制研究

81901565
2019
H0422.生殖系统/围生医学/新生儿疾病研究新技术与新方法
魏晓伟
青年科学基金项目
副研究员
中国医科大学
20万元
产前治疗;干细胞移植;基因治疗;神经管畸形
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Intra-amniotic delivery of CRMP4 siRNA improves mesenchymal stem cell therapy in a rat spina bifida model 期刊论文 Wei Xiaowei;Cao Songying;Ma Wei;Zhang Chaonan;Gu Hui;Liu Dan;Luo Wenting;Bai Yuzuo;Wang Weilin;Yuan Zhengwei
2 用于唇腭裂、神经管畸形和先天性心脏病胎儿产前无创诊断的分子标志物及其应用 专利 袁正伟;贾杉杉;顾卉;魏晓伟;马巍;刘丹;罗文婷
3 常见小儿先天畸形早期诊治关键技术与转化应用 奖励 袁正伟;任爱国;张霆;顾卉;魏晓伟;马巍;刘丹;陈骊珠;张赫楠;安东;杨中华
4 Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects 期刊论文 Wanqi Huang;Tianchu Huang;Yusi Liu;Jialin Fu;Xiaowei Wei;Dan Liu;Wei Ma;Hui Gu;Zhengwei Yuan
5 Intra-amniotic transplantation of brain-derived neurotrophic factor-modified mesenchymal stem cells treatment for rat fetuses with spina bifida aperta 期刊论文 Wei Ma;Xiaowei Wei;Hui Gu;Dan Liu;Wenting Luo;Songying Cao;Shanshan Jia;Yiwen He;Lizhu Chen;Yuzuo Bai;Zhengwei Yuan
6 Intra‐amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses 期刊论文 Xiaowei Wei;Wei Ma;Hui Gu;Dan Liu;Wenting Luo;Songying Cao;Shanshan Jia;Tianchu Huang;Yiwen He;Yuzuo Bai;Weilin Wang;Zhengwei Yuan
7 Amniotic fluid mesenchymal stromal cells from early stages of embryonic development have higher self-renewal potential 期刊论文 Jieting Huang;Wei Ma;Xiaowei Wei;Zhengwei Yuan
8 用于唇腭裂产前无创诊断的分子标志物及其应用 专利 袁正伟;贾杉杉;顾卉;魏晓伟;马巍;刘丹;罗文婷
9 Transamniotic mesenchymal stem cell therapy for neural tube defects preserves neural function through lesion-specific engraftment and regeneration 期刊论文 Xiaowei Wei;Wei Ma;Hui Gu;Dan Liu;Wenting Luo;Yuzuo Bai;Weilin Wang;Vincent Chi Hang Lui;Peixin Yang;Zhengwei Yuan
10 Therapeutic potential of adenovirus-encoding brain-derived neurotrophic factor for spina bifida aperta by intra-amniotic delivery in a rat model 期刊论文 Ma Wei;Wei Xiaowei;Gu Hui;Liu Dan;Luo Wenting;An Dong;Bai Yuzuo;Yuan Zhengwei
11 一种与干细胞增殖相关的Abca4基因及其应用 专利 袁正伟;黄捷婷;顾卉;魏晓伟;马巍;刘丹;罗文婷
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