NF-κB/GAS5/miR-26a/ROCK1信号轴参与调控心肌缺血再灌注损伤的机制研究

81800232
2018
H0202.心肌损伤、修复、重构和再生
吴楠
青年科学基金项目
副研究员
中国医科大学
21万元
长链非编码RNA;竞争性内源;RNA;微小RNA;心肌缺血再灌注损伤;Rho激酶
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 LncRNA MEG3 inhibits cell proliferation and induces apoptosis in laryngeal cancer via miR-23a/APAF-1 axis 期刊论文 Zhang Xiaowen;Wu Nan;Wang Jin;Li Zhijie
2 Brazilin prevents against myocardial ischemia-reperfusion injury through the modulation of Nrf2 via the PKC signaling pathway 期刊论文 Qi Bin;Zhang Xiaowen;Yu Hang;Bao Yandong;Wu Nan;Jia Dalin
3 Hsa-circ_0058106 induces EMT and metastasis in laryngeal cancer via sponging miR-153 and inducing Twist1 nuclear translocation 期刊论文 Zhang Xiaowen;Wu Nan;Wang Jin
4 Down-regulation of GAS5 ameliorates myocardial ischaemia/reperfusion injury via the miR-335/ROCK1/AKT/GSK-3 beta axis 期刊论文 Wu Nan;Zhang Xiaowen;Bao Yandong;Yu Hang;Jia Dalin;Ma Chunyan
5 Pharmacological postconditioning with sappanone A ameliorates myocardial ischemia reperfusion injury and mitochondrial dysfunction via AMPK-mediated mitochondrial quality control 期刊论文 Shi Xiaojing;Li Yang;Wang Yaguang;Ding Tiejia;Zhang Xiaowen;Wu Nan
6 miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a 期刊论文 Bao Yandong;Qiao Ying;Yu Hang;Zhang Zeying;Yang Huimin;Xin Xin;Chen Yuqiong;Guo Yuxuan;Wu Nan;Jia Dalin
7 Lycopene restores the effect of ischemic postconditioning on myocardial ischemia-reperfusion injury in hypercholesterolemic rats 期刊论文 Duan Lian;Liang Changbin;Li Xuying;Huang Zijun;Liu Shuang;Wu Nan;Jia Dalin
8 Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore 期刊论文 Yanbing Zhao;Yuxuan Guo;Yuqiong Chen;Shuang Liu;Nan Wu;Dalin Jia
9 Upregulation of miR-335 ameliorates myocardial ischemia reperfusion injury via targeting hypoxia inducible factor 1-alpha subunit inhibitor. 期刊论文 Wu Nan;Zhang Xiaowen;Du Shuyan;Chen Dong;Che Ruichao
10 Sweroside Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Pyroptosis Partially via Modulation of the Keap1/Nrf2 Axis 期刊论文 Li Jun;Zhao Cuiting;Zhu Qing;Wang Yonghuai;Li Guangyuan;Li Xinxin;Li Yuhong;Wu Nan;Ma Chunyan
11 miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1 期刊论文 Xin Xin;Duan Lian;Yang Huimin;Yu Hang;Bao Yandong;Jia Dalin;Wu Nan;Qiao Ying
12 高脂血症对心肌缺血再灌注损伤的影响 期刊论文 吴楠;张晓雯
13 microRNA Expression Profiles in Myocardium of High-Fat Diet-Induced Obesity Rat 期刊论文 Huimin Yang;Xin， Xin;Hang Yu;Yandong Bao;Pengyu Jia;Nan Wu;Dalin Jia
14 Hydroxytyrosol protects against myocardial ischemia reperfusion injury by inhibiting mitochondrial permeability transition pore opening 期刊论文 Miao Jiaxin;Huang Zijun;Liu Shuang;Li Xuying;Jia Pengyu;Guo Yuxuan;Wu Nan;Jia Dalin
15 Downregulation of MALAT1 alleviates saturated fatty acid-induced myocardial inflammatory injury via the miR-26a/HMGB1/TLR4/NF-kappa B axis 期刊论文 Jia Pengyu;Wu Nan;Jia Dalin;Sun Yingxian
16 Lycopene protects against myocardial ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening 期刊论文 Li Xuying;Jia Pengyu;Huang Zijun;Liu Shuang;Miao Jiaxin;Guo Yuxuan;Wu Nan;Jia Dalin
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