基于脂质组学研究神经酰胺诱导的氧化应激在狼疮性肾炎发病中的作用及狼疮定的治疗机制探讨
81803861
2018
H3301.中西医结合基础理论
胡长锋
青年科学基金项目
副研究员
浙江中医药大学
21万元
氧化应激;糖皮质激素;脂质组学;神经酰胺;狼疮性肾炎
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Recognition and avoidance of ion source-generated artifacts in lipidomics analysis | 期刊论文 | Hu Changfeng;Luo Wenqing;Xu Jie;Han Xianlin |
| 2 | Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus | 期刊论文 | Hu Changfeng;Zhang J;Hong S;Li H;Lu L;Xie G;Luo W;Du Y;Xie Z;Han X;Wen C |
| 3 | Strategies to improve/eliminate the limitations in shotgun lipidomics | 期刊论文 | Hu Changfeng;Duan Q;Han X |
| 4 | Lipidomics revealed aberrant metabolism of lipids including FAHFAs in renal tissue in the progression of lupus nephritis in a murine model | 期刊论文 | Hu Changfeng;Du Y;Xu X;Li H;Duan Q;Xie Z;Wen C;Han X |
| 5 | Sensitive analysis of fatty acid esters of hydroxy fatty acids in biological lipid extracts by shotgun lipidomics after one-step derivatization | 期刊论文 | Hu Changfeng;Wang M;Duan Q;Han X |
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