PLD2调控mTOR/HIF-1α/VEGF信号通路在脓毒症NETs损害肠黏膜屏障的作用机制

81770532
2017
H0304.消化道内环境紊乱、黏膜屏障障碍及相关疾病
丁威威
面上项目
副主任医师
南京大学
56万元
肠黏膜屏障功能障碍;脓毒症;炎症;中性粒细胞;腹腔感染
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Outcomes and clinical characteristics of transmural intestinal necrosis in acute mesenteric ischemia 期刊论文 Wang Xinyu;Chu Chengnan;Sun Shilong;Xie Tian;Duan Zehua;Wang Kai;Liu Baochen;Fan Xinxin;Wu Xingjiang;Ding Weiwei
2 血清cf-DNA对腹部外伤合并脓毒症患者预后的预测价值 期刊论文 王永乐;王凯;王士凯;孙世龙;谢天;丁威威
3 腹腔开放肠空气瘘辅助恢复装置 专利 丁威威;刘宝晨;殷伟;吴翠丽;叶向红;王新宇;储成楠;杨超
4 用于肠空气瘘辅助恢复的装置、使用方法及预警方法 专利 丁威威;刘宝晨;殷伟;吴翠丽;黎介寿
5 Protective effect of ethyl pyruvate on gut barrier function through regulations of ROS-related NETs formation during sepsis 期刊论文 Wang Xinyu;Sun Shilong;Duan Zehua;Yang Chao;Chu Chengnan;Wang Kai;Liu Baochen;Ding Weiwei;Li Weiqin;Li Jieshou
6 胰腺外伤单中心136例诊治报告 期刊论文 丁威威;王凯;刘宝晨;习丰产;汪志明;李维勤;黎介寿
7 中性粒细胞胞外诱捕网与肠屏障功能障碍的研究进展 期刊论文 谢天;丁威威
8 胰腺外伤的诊治新进展 期刊论文 王永乐;丁威威
9 Predictors of irreversible intestinal resection in patients with acute mesenteric venous thrombosis 期刊论文 Sun Shi-Long;Wang Xin-Yu;Chu Cheng-Nan;Liu Bao-Chen;Li Qiu-Rong;Ding Wei-Wei
10 Neutrophil extracellular trap formation index predicts occurrences of deep surgical site infection after laparotomy 期刊论文 Duan Zehua;Sun Shilong;Qu Cheng;Wang Kai;Chen Fang;Wang Xinyu;Chu Chengnan;Liu Baochen;Li Jieshou;Ding Weiwei
11 beta-Lactams modulate neutrophil extracellular traps formation mediated by mTOR signaling pathway 期刊论文 Xie Tian;Duan Zehua;Sun Shilong;Chu Chengnan;Ding Weiwei
12 循环游离DNA在脓毒症中的研究进展 期刊论文 王士凯;丁威威
13 Early intravenous administration of tranexamic acid ameliorates intestinal barrier injury induced by neutrophil extracellular traps in a rat model of trauma/hemorrhagic shock. 期刊论文 Chu C;Yang C;Wang X;Xie T;Sun S;Liu B;Wang K;Duan Z;Ding W;Li J
14 江苏省医学新技术引进奖 奖励 丁威威;刘宝晨;吴性江
15 Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway 期刊论文 Sun Shilong;Duan Zehua;Wang Xinyu;Chu Chengnan;Yang Chao;Chen Fang;Wang Daojuan;Wang Chenyang;Li Qiurong;Ding Weiwei
16 Endovascular stent placement for isolated superior mesenteric artery dissection with intestinal ischaemia 期刊论文 Baochen Liu;Chengnan Chu;Xinxin Fan;Weiwei Ding;Xingjiang Wu
17 胰腺损伤再剖腹手术的危险因素分析 期刊论文 王永乐;丁威威;孙世龙;王士凯;谢天;王凯;吴性江;黎介寿
18 多位置可调肠瘘辅助恢复装置 专利 丁威威;刘宝晨;殷伟;吴翠丽;黎介寿
19 自调节球囊阻断装置 专利 丁威威;刘宝晨
20 直视下血管修补装置 专利 丁威威;刘宝晨
21 1例严重腹部外伤病人行多造口的接力式肠内营养实施与管理 期刊论文 吴翠丽;吴晓鹃;叶向红;丁威威
22 Bioelectrical impedance analysis-guided fluid management promotes primary fascial closure after open abdomen: a randomized controlled trial 期刊论文 Wang Kai;Sun Shi-Long;Wang Xin-Yu;Chu Cheng-Nan;Duan Ze-Hua;Yang Chao;Liu Bao-Chen;Ding Wei-Wei;Li Wei-Qin;Li Jie-Shou
23 De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis 期刊论文 Duan Zehua;Xie Tian;Chu Chennan;Chen Fang;Wang Xinyu;Li Jieshou;Ding Weiwei
24 DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury 期刊论文 Shikai Wang;Tian Xie;Shilong Sun;Kai Wang;Baochen Liu;Xingjiang Wu;Weiwei Ding
25 A case-control study of risk factors for survival after laparotomy in patients with pancreatic trauma. 期刊论文 Yang Chao;Wang Xinyu;Wu Cuili;Wang Yongle;Wang Kai;Ding Weiwei
26 一例急性肠系膜上动脉栓塞的营养支持治疗 期刊论文 刘宝晨;丁威威;范欣鑫;吴性江;黎介寿
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