肝素在脓毒症内皮细胞损伤中调控MyD88依赖的TLR-4途径炎症基因表达的作用机制研究

81101411
2011
H1601.脓毒症
李旭
青年科学基金项目
教授
中国医科大学
20万元
血管内皮细胞;脓毒症;普通肝素;核因子-κB
2012-01-01到2014-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 HMGB1基因真核细胞表达载体的构建及其在人脐静脉血管内皮细胞中的表达 期刊论文 张晓娟|李旭|栾正刚|马晓春|
2 <span class="highlight">Unfractionated heparin</span> attenuates <span class="highlight">LPS</span>-induced IL-8 secretion via PI3K/Akt/NF-κB signaling pathway in human <span class="highlight">en 期刊论文 Xu Li|Yina Liu|Liang Wang|Zhiliang Li|Xiaochun Ma|
3 Unfractionated heparin promotes LPS-induced endothelial barrier dysfunction: a preliminary study on the roles of angiopoietin/Tie2 axis 期刊论文 Xu Li|Zhen Zheng|Yiran Mao|Xiaochun Ma|
4 肝素通过TLR4减少脂多糖刺激的人内皮细胞IL-8表达 期刊论文 李旭|李鑫|马晓春|
5 Unfractionated heparin suppresses lipopolysaccharide-inducedmonocyte chemoattractant protein-1 expression in humanmicrovascular endothelial cells by blocking Krüppel-like factor 5 andnuclear factor-B pathway 期刊论文 Xu Li|Xin Li|Zhen Zheng|Yina Liu|Xiaochun Ma|
6 肝素对脂多糖诱导内皮细胞损伤中基质金属蛋白酶及其组织抑制剂基因表达的影响 期刊论文 李旭|张晓娟|马晓春|
7 Artificial and bioartificial liver support systems for acute and acute-on-chronic hepatic failure: A meta-analysis and meta-regression 期刊论文 Zhen Zheng|Xu Li|Zhiliang Li|Xiaochun Ma|
8 肝素对急性肺损伤大鼠基质金属蛋白酶2和9活性的影响 期刊论文 李旭|郑振|马晓春|
9 Unfractionated Heparin Ameliorates Lipopolysaccharide-Induced Lung Inflammation by Downregulating Nuclear Factor-κB Signaling Pathway 期刊论文 Xu Li|Zhiliang Li|Zhen Zheng|Yina Liu|Xiaochun Ma|
10 Unfractionated heparin inhibits lipopolysaccharide-induced inflammatory response through blocking p38 MAPK and NF-kappa B activation on endothelial cell 期刊论文 Xu Li|Zhen Zheng|Xin Li|Xiaochun Ma|
11 Unfractionated heparin inhibits lipopolysaccharide-induced inflammatory response through blocking p38 MAPK and NF-&kappa;B activation on endothelial cell 期刊论文 李旭|
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