【30973079】Caveolin-1对血肿瘤屏障紧密连接调节机制的研究国家自然基金项目

Caveolin-1对血肿瘤屏障紧密连接调节机制的研究

项目批准号： 30973079

批准年份： 2009

学科分类： H1817.肿瘤物理治疗

项目负责人：薛一雪

资助类别：面上项目

负责人职称：教授

依托单位：中国医科大学

资助金额： 30万元

关键词： caveolin-1;低频超声;脑胶质瘤;血肿瘤屏障;紧密连接

起止时间： 2010-01-01到2012-12-31

中英文摘要
结题摘要
结题报告
项目成果
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序号	标题	类型	作者
1	Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood-Brain Barrier in a Focal Cerebral Ischemic Insult	期刊论文	Jiao Haixia\|Wang Zhenhua\|Liu Yunhui\|Wang Ping\|Xue Yixue\|
2	Role of RhoA/ROCK Signaling in Endothelial-Monocyte-Activating Polypeptide II Opening of the Blood-Tumor Barrier	期刊论文	Xie Hui\|Xue Yi-xue\|Liu Li-bo\|Liu Yun-hui\|Wang Ping\|
3	缓激肽对大鼠脑胶质瘤微血管中NF-κ B活性和表达的影响	期刊论文	刘丽波\|马腾\|陈方圆\|解辉\|薛一雪\|
4	The modulation of protein kinase A and heat shock protein 70 is involved in the reversible increase of blood-brain tumor barrier permeability induced by papaverine	期刊论文	Wang Zhen-hua\|Xue Yi-xue\|Liu Yun-hui\|
5	RhoA参与缓激肽调节紧密连接相关蛋白occludin分布和表达的作用	期刊论文	马腾\|王萍\|薛一雪\|
6	血脑屏障氧糖剥夺体外模型大鼠脑微血管内皮细胞miRNA表达变化	期刊论文	马腾\|刘丽波\|王萍\|刘云会\|薛一雪\|
7	Low-Frequency Ultrasound Irradiation Increases Blood-Tumor Barrier Permeability by Transcellular Pathway in a Rat Glioma Model	期刊论文	Xia, Chun-yi\|Liu, Yun-hui\|Wang, Ping\|Xue, Yi-xue\|
8	RhoA在缓激肽选择性开放血肿瘤屏障中的作用	期刊论文	马腾\|刘啸白\|薛一雪\|
9	Increasing of Blood-tumor Barrier Permeability through Paracellular Pathway by Low-frequency Ultrasound Irradiation In Vitro	期刊论文	Fan Lilin\|Liu Yunhui\|Ying Haoqiang\|Xue Yixue\|Zhang Zhen\|Wang Ping\|Liu Libo\|Zhang Hua\|
10	Mechanism of Low-Frequency Ultrasound in Opening Blood-Tumor Barrier by Tight Junction	期刊论文	Shang Xiuli\|Wang Ping\|Liu Yunhui\|Zhang Zhen\|Xue Yixue\|
11	交叉反应物质197转运大分子物质通过血肿瘤屏障的效果和机制	期刊论文	王萍\|刘云会\|薛一雪\|
12	内皮-单核细胞激活多肽酶Ⅱ增强血肿瘤屏障通透性的机制	期刊论文	李振\|刘云会\|薛一雪\|刘立波\|LI Zhen1,LIU Yun-hui1,XUE Yi-xue2,LIU Li-bo2(1.Dep\|2.Department of Neurobiology,College of Basic Medi\|
13	大鼠原代脑微血管内皮细胞体外分离与培养的实验研究	期刊论文	李振\|刘云会\|薛一雪\|刘丽波\|王萍\|LI Zhen1,LIU Yun-hui1,XUE Yi-xue2,LIU Li-bo2,WANG\|2.Department of Neurobiology,College of Basic Medi\|
14	EMAP-Ⅱ对紧密连接相关蛋白occludin和ZO-1相互作用的调节和机制	期刊论文	王佐周\|刘丽波\|薛一雪\|刘云会\|WANG Zuo-zhou1,LIU Li-bo2,XUE Yi-xue2,LIU Yun-hui3\|2.Department of Neurobiology,College of Basic Medi\|3.Department of Neurosurgery,Shengjing Hospital,Ch\|
15	蛋白激酶C在内皮-单核细胞激活多肽Ⅱ增强血肿瘤屏障通透性中的作用	期刊论文	李振\|刘云会\|薛一雪\|刘丽波\|王萍\|
16	Vascular Endothelial Growth Factor Increases Permeability of the Blood-Tumor Barrier via Caveolae-Mediated Transcellular Pathway	期刊论文	Zhao Li-ni\|Yang Zhi-hang\|Liu Yun-hui\|Ying Hao-qiang\|Zhang Hua\|Xue Yi-xue\|
17	Role of ATP synthase alpha subunit in low-dose endothelial monocyte-activating polypeptide-II-induced opening of the blood-tumor barrier	期刊论文	Li Zhen\|Liu Yun-hui\|Xue Yi-xue\|Xie, Hui\|Liu Li-bo\|
18	缓激肽对脑胶质瘤大鼠血肿瘤屏障紧密连接相关蛋白分布和表达的影响	期刊论文	刘丽波\|薛一雪\|马腾\|
19	RhoA-Mediated Potential Regulation of Blood-Tumor Barrier Permeability by Bradykinin	期刊论文	Ma Teng\|Xue Yixue\|
20	CRM197-Induced Blood-Brain Barrier Permeability Increase is Mediated by Upregulation of Caveolin-1 Protein	期刊论文	Wang Ping\|Liu Yunhui\|Shang Xiuli\|Xue Yixue\|
21	Bradykinin increases the permeability of the blood-tumor barrier by the caveolae-mediated transcellular pathway	期刊论文	Liu Li-bo\|Xue Yi-xue\|Liu Yun-hui\|
22	Evidence for involvement of ROCK signaling in bradykinin-induced increase in murine blood-tumor barrier permeability	期刊论文	Ma Teng\|Liu Libo\|Wang Ping\|Xue Yixue\|
23	C_3胞外酶抑制缓激肽诱导的血肿瘤屏障通透性的增加	期刊论文	马腾\|刘啸白\|薛一雪\|

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