蝎毒多肽martentoxin靶向大电导钙激活钾通道（BK）的抗癫痫机制研究
81603410
2016
H3301.中西医结合基础理论
陶杰
青年科学基金项目
助理研究员
上海中医药大学
17万元
全蝎;海马锥体神经元;膜片钳;离子通道;癫痫
2017-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | SCN9A Epileptic Encephalopathy Mutations Display a Gain-of-function Phenotype and Distinct Sensitivity to Oxcarbazepine | 期刊论文 | Zhang Shuzhang;Zhang Zhiping;Shen Yuan;Zhu Yudan;Du Kun;Guo Jingkang;Ji Yonghua;Tao Jie |
| 2 | 钾离子通道kv1.3的调制剂Bmp02及其应用 | 专利 | 吴宝芬;陶杰;冯逸俊;吉永华;郭景康 |
| 3 | Modulatory effects of bufalin, an active ingredient from toad venom on voltage-gated sodium channels | 期刊论文 | Tao Jie;Jiang Feng;Liu Cheng;Liu Zhirui;Zhu Yudan;Xu Jian;Ge Yiqin;Xu Kan;Yin Peihao |
| 4 | BK ablation attenuates osteoblast bone formation via integrin pathway | 期刊论文 | Wang Yinhang;Guo Qiang;Hei Hongya;Tao Jie;Zhou Yi;Dong Jibin;Xin Hong;Cai Hui;Gao Jianjun;Yu Ker;Reilly Svetlana;Yin Peihao;Zhang Xuemei |
| 5 | 第二届中国东西部抗癌痛国际会议暨神经感知与肿瘤调控国际研讨会,优秀论文奖 | 奖励 | 陶杰 |
| 6 | 单味中药及单体有效成分对抗癫痫机理实验研究简况 | 期刊论文 | 申梅;陶杰;徐侃 |
| 7 | Ion Channels in Epilepsy: Blasting Fuse for Neuronal Hyperexcitability | 专著 | Zhang Shuzhang;Zhu Yudan;Cheng Jiwei;Tao Jie |
| 8 | The Yin and Yang of BK Channels in Epilepsy | 期刊论文 | Zhu Yudan;Zhang Shuzhang;Feng Yijun;Xiao Qian;Cheng Jiwei;Tao Jie |
| 9 | Selective Blockade of Neuronal BK (α β4) Channels Preventing Epileptic Seizure | 期刊论文 | Liu Xinlian;Tao Jie;Zhang Shuzhang;Lan Wenxian;Wang Chunxi;Ji Yonghua;Cao Chunyang |
| 10 | Scorpion Toxins from Buthus martensii Karsch (BmK) as Potential Therapeutic Agents for Neurological Disorders: State of the Art and Beyond | 专著 | Wang Xiaoli;Zhang Shuzhang;Zhu Yudan;Zhang Zhiping;Sun Mengyao;Cheng Jiwei;Xiao Qian;Li Guoyi;Tao Jie |
| 11 | Kv1.3 Channel as a Key Therapeutic Target for Neuroinflammatory Diseases: State of the Art and Beyond | 期刊论文 | Wang Xiaoli;Li Guoyi;Guo Jingkang;Zhang Zhiping;Zhang Shuzhang;Zhu Yudan;Cheng Jiwei;Yu Lu;Ji Yonghua;Tao Jie |
| 12 | 重组Martentoxin的制备、表征及应用 | 专利 | 曹春阳;刘新莲;陶杰;吉永华;蓝文贤 |
| 13 | 定痫丸对难治性癫痫大鼠抗痫作用及其对MDR1/P-gp表达的影响 | 期刊论文 | 程记伟;陶杰;张淑芬;李国毅;陈黎佶;张晓菁;朱宇丹;白宇 |
| 14 | Anticonvulsant Effects of Dingxian Pill in Pentylenetetrazol-Kindled Rats | 期刊论文 | Zhu Yudan;Zhang Shuzhang;Shen Mei;Zhang Zhiping;Xu Kan;Cheng Jiwei;Ge Yiqin;Tao Jie |
| 15 | Understanding Genotypes and Phenotypes of the Mutations in Voltage- Gated Sodium Channel alpha Subunits in Epilepsy | 期刊论文 | Feng Yijun;Zhang Shuzhang;Zhang Zhiping;Guo Jingkang;Tan Zhiyong;Zhu Yudan;Tao Jie;Ji Yonghua |
| 16 | Mechanism of Regulation of Big-Conductance Ca(2 )-Activated K( ) Channels by mTOR Complex 2 in Podocytes | 期刊论文 | Wang Yinhang;Tao Jie;Wang Mengling;Yang Licai;Ning Fengling;Xin Hong;Xu Xudong;Cai Hui;Zhang Weiguang;Yu Ker;Zhang Xuemei |
| 17 | 抗癫痫的毒素Martentoxin及其应用 | 专利 | 曹春阳;吉永华;刘新莲;陶杰;张淑章;王春喜 |
| 18 | Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of alphasynuclein methylation | 期刊论文 | Zhao Qing;Liu Hui;Cheng Jiwei;Zhu Yudan;Xiao Qian;Bai Yu;Tao Jie |
| 19 | 第十四届中国生物毒素毒理学术大会,海报二等奖 | 奖励 | 陶杰 |
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