活细胞内特异性检测与标记蛋白亚磺酸的分子荧光探针构筑及成像研究

21778026
2017
B0701.生物体系分子探针
张良伟
面上项目
副研究员
兰州大学
64万元
小分子荧光探针;蛋白标记;成像;蛋白亚磺酸
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 一种用于多硫化物检测的荧光探针化合物及其制备方法 专利 陈令新;王悦;张良伟
2 基于氢键及去质子化设计的氟离子荧光探针 会议论文 刘姝菂;张良伟
3 A chemical covalent tactic for bio-thiol sensing and protein labeling agent design 期刊论文 Zhang Liangwei;Kang Jie;Liu Shudi;Zhang Xia;Sun Jinyu;Hu Yuesong;Yang Yang;Chen Lingxin
4 High Spatiotemporal Resolution Observation of Glutathione Hydropersulfides in Living Cells and Tissue via a Two-Photon Ratiometric Fluorescent Probe 期刊论文 Wang Yue;Zhang Liangwei;Zhang Songzi;Liu Zhe;Chen Lingxin
5 A small molecule fluorescent probe for mercury ion analysis in broad low pH range: Spectral, optical mechanism and application studies 期刊论文 Liu Shudi;Zhang Xia;Yan Chaoxian;Zhou Panpan;Zhang Li;Li Qingzhong;Zhang Renjie;Chen Lingxin;Zhang Liangwei
6 A reaction-based ratiometric fluorescent probe for mercury ion detection in aqueous solution 期刊论文 Liu Shudi;Feng Di;Zhang Liangwei;Song He;Wang Yue;Zhang Xia;Zhao Qingjun;Chen Lingxin
7 Visualizing and evaluating mitochondrial cysteine via near-infrared fluorescence imaging in cells, tissues and in vivo under hypoxia/ reperfusion stress 期刊论文 Zhang Xia;Zhang Liangwei;Wang Xiaoyan;Han Xiaoyue;Huang Yan;Li Bowei;Chen Lingxin
8 近红外荧光成像评价线粒体谷胱甘肽对脑缺血再灌注损伤的保护作用 会议论文 张霞;张良伟;陈令新
9 A ratiometric fluorescent probe of methionine sulfoxide reductase with an improved response rate and emission wavelength 期刊论文 Zhang Liangwei;Peng Shoujiao;Sun Jinyu;Liu Ruijuan;Liu Shudi;Fang Jianguo
10 Fluorescent probe for mercury ion imaging analysis: Strategies and applications 期刊论文 Yue Wang;Li Zhang;Xiaoyue Han;Liangwei ZHang;Xiaoyan Wang;Lingxin Chen
11 A cysteine-selective fluorescent probe for monitoring stress response cysteine fluctuations 期刊论文 Yang Yang;Zhang Liangwei;Zhang Xia;Liu Shudi;Wang Yue;Zhang Li;Ma Zhuo;You Huiyan;Chen Lingxin
12 A near-infrared fluorescent probe for observing thionitrous acid-mediated hydrogen polysulfides formation and fluctuation in cells and in vivo under hypoxia stress 期刊论文 Zhang Xia;Zhang Liangwei;Gao Min;Wang Yunqing;Chen Lingxin
13 Insight into sulfur dioxide and its derivatives metabolism in living system with visualized evidences via ultra-sensitive fluorescent probe 期刊论文 Zhang Xia;Zhang Li;Liu Shudi;Zhu Xiaozhen;Zhou Panpan;Cheng Xinyan;Zhang Renjie;Zhang Liangwei;Chen Lingxin
14 一种检测半胱氨酸的荧光探针化合物及应用 专利 陈令新;张霞;张良伟;韩潇玥;高敏
15 Reaction-based ratiometric fluorescent probe for Mercury ion (II) detection in aqueous solution 会议论文 Shudi Liu;Liangwei Zhang;Linxin Chen
16 Evaluating the Protective Effects of Mitochondrial Glutathione on Cerebral Ischemia/Reperfusion Injury via Near-Infrared Fluorescence Imaging 期刊论文 Zhang Xia;Huang Yan;Han Xiaoyue;Wang Yue;Zhang Liangwei;Chen Lingxin
17 A novel broad-range low pH mercury fluorescent probe: spectral, mechanism and application studies 会议论文 Liangwei Zhang;Shudi Liu;Linxin Chen
18 Glutathione Peroxidase-Activatable Two-Photon Ratiometric Fluorescent Probe for Redox Mechanism Research in Aging and Mercury Exposure Mice Models 期刊论文 Wang Yue;Zhang Liangwei;Chen Lingxin
19 Evaluation of cyclooxygenase-2 fluctuation via a near-infrared fluorescent probe in idiopathic pulmonary fibrosis cell and mice models 期刊论文 Wang Yude;Wei Yinghui;He Na;Zhang Liangwei;You Jinmao;Chen Lingxin;Lv Changjun
20 Rational design of a nitroreductase-activatable two-photon fluorescent probe for hypoxia imaging in cell and in vivo 期刊论文 Wang Yue;Zhang Li;Huang Yan;Wang Xiaoyan;Zhang Liangwei;Chen Lingxin
21 一种荧光探针及其制备方法和应用 专利 张良伟;刘姝菂;陈令新
22 基于甲基亚砜标记蛋白巯基试剂的发展及应用 会议论文 康洁;刘姝菂;朱倩;张良伟
23 活细胞内动态监测锌离子波动的荧光探针 会议论文 刘姝菂;张良伟
24 一种用于检测多硫化氢的荧光探针及其制备方法和应用 专利 陈令新;张良伟;张霞;杨阳;张丽
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