脱水酶的高级结构肽模拟物的设计、合成及其催化β-羰基醇脱水反应过程中的手性识别作用研究

21072087
2010
B0111.仿生与绿色合成
达朝山
面上项目
教授
兰州大学
36万元
多肽酶模拟物;高级结构;手性识别;脱水酶;脱水反应
2011-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Highly catalytic enantioselective synthesis of medically interesting secondary arylpropanols with Grignard reaction 会议论文 Chao-Shan Da|Yi Liu|Xiao-Gang Yin|Jun-Rui Wang|Xin-Yuan Fan|Wei-Ping Li|Rui Yuan|Pei Wang|Rui Wang|
2 Highly enantioselective biomimetic intramolecular dehydration: kinetic resolution of beta-hydroxy ketones catalyzed by beta-turn tetrapeptides 期刊论文 Du, Zhi-Xue|Zhang, Li-Yuan|Fan, Xin-Yuan|Wu, Feng-Chun|Da, Chao-Shan|
3 Site-Specific ortho-Arylation of N-Heteroarenes with Aryl Grignard Reagents Assisted by TMEDA 会议论文 Zhuo Fang-Fang|Xie Wen-Wen|Yang Yong-Xin|Zhang Lei|Wang, Pei|Yuan Rui|Da Chao-Shan|
4 Catalytic Highly Enantioselective Alkylation of Aldehydes with Deactivated Grignard Reagents and Synthesis of Bioactive Intermediate Secondary Arylpropanols 期刊论文 Yi Liu|Chao-Shan Da|Sheng-Li Yu|Xiao-Gang Yin|Jun-Rui Wang|Xin-Yuan Fan|Wei-Ping Li|Rui Wang|
5 The Catalytic Asymmetric Addition of in situ Generated Aryllithiums to Cinnamaldehydes: Effectively Synthesize Enantioenriched Linear Trisubstituted Allylic Alcohols 会议论文 Zhang Lei|Sun Lin|Li Yu-Yan|Liu Yue|Yang Yong-Xin|Yuan Rui|Wang Pei|Da Chao-Shan|
6 TMEDA-Assisted Effective Direct Ortho Arylation of Electron-Deficient N-Heteroarenes with Aromatic Grignard Reagents 期刊论文 Zhuo, Fang-Fang|Xie, Wen-Wen|Yang, Yong-Xin|Zhang, Lei|Wang, Pei|Yuan, Rui|Da, Chao-Shan|
7 Catalytic Asymmetric Arylation of Enals to Enantioenriched Linear Trisubstituted Allylic Secondary Alcohols by using Aryl Lithiums Generated In Situ from Aryl Bromides 期刊论文 Lei Zhang|Lin Sun|Yu-Yan Li|Yue Liu|Yong-Xin Yang|Rui Yuan|Pei Wang|Chao-Shan Da|
8 Primary amine organocatalyst catalyzed atom-specific reaction: asymmetric addition of aldehydes to nitrosobenzene 会议论文 Chao-Shan Da|Long Qin|Lei Li|Lei Yi|
9 Direct Asymmetric N-Specific Reaction of Nitrosobenzene with Aldehydes Catalyzed by a Chiral Primary Amine-Based Organocatalyst 期刊论文 Qin, Long|Li, Lei|Yi, Lei|Da, Chao-Shan|Zhou, Yi-Feng|
10 β-Turn Tetrapeptides as Effective Enzyme-Like Catalysts for Kinetic Resolution of Racemic Hydroxyl Ketones 会议论文 Du Zhi-xue|Zhang Li-Yuan|Da Chao-Shan|
11 Kinetic Resolution of Racemic Hydroxyl Ketones Catalyzed by β-Turn Tetrapeptides 会议论文 Zhi-xue Du|Li-Yuan Zhang|Chao-Shan Da|
12 C2-Symmetric Homobimetallic Zinc Complexes as Chiral Catalysts for the Highly Enantioselective Hydrophosphonylation of Aldehydes 期刊论文 Lin Sun|Qi-Peng Guo|Xiao Li|Lei Zhang|Yu-Yan Li|Chao-Shan Da|
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