阴虚血瘀证肺腺癌中MACC1蛋白介导非肿瘤干细胞向肿瘤干细胞“逆演进”调控网路障碍和滋阴化瘀法干预机制

81774078
2017
H3302.中西医结合临床基础
顾春东
面上项目
教授
大连医科大学
55万元
肿瘤干细胞;MACC1;滋阴化瘀法;阴虚血瘀证;肺腺癌
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 New additional scoring formula on the Pathological Features in Stage I Lung Adenocarcinoma Patients: Impact on Survival 期刊论文 Shilei Zhao;Fengzhou Li;Xin Guo;Tao Guo;Ken-ichi Mizutani;Sohasuke Yamada;Chundong Gu;Hidetaka Uramoto
2 LCSCAF1 maintains cancer stem-like traits by stabilizing c-Myc protein and promotes metastasis and recurrence in lung cancer 会议论文 T. Guo;L. Zhao;S. Zhao;C. Gu
3 The Nutritional Cytokine Leptin Promotes NSCLC by Activating the PI3K/AKT and MAPK/ERK Pathways in NSCLC Cells in a Paracrine Manner 期刊论文 Li Fengzhou;Zhao Shilei;Guo Tao;Li Jinxiu;Gu Chundong
4 Overexpression of Teashirt Homolog 2 suppresses cell proliferation and predicts the favorable survival of Lung Adenocarcinoma 期刊论文 Shilei Zhao;Xin Guo;Ken-ichi Mizutani;Reimon Yamaguchi;Sohsuke Yamada;Chundong Gu;Hidetaka Uramoto
5 The Antitumor Efficacy of β-Elemene by Changing Tumor Inflammatory Environment and Tumor Microenvironment 期刊论文 Qiang Xie;Fengzhou Li;Lei Fang;Wenzhi Liu;Chundong Gu
6 Highly Sensitivity and Fast Genetic Diagnosis by Mean of a Novel NGS-Based Resequencing Gene Panel Underlying SCLC Patients 会议论文 J. Wang;L. Zhao;X. Sun;F. Zhou;Y. Zhang;S. Zhao;S. Liu;L. Chin;L. Wang;T. Guo;Z. Sun;F. Li;C. Gu
7 Genetic Mutation Analysis in Small Cell Lung Cancer by a Novel NGS-Based Targeted Resequencing Gene Panel and Relation with Clinical Features 期刊论文 Wang Jin;Zhao Lei;Sun Xu;Zhou Fachen;Zhang Yixiang;Zhao Shilei;Guo Tao;Sun Zhe;Li Fengzhou;Sun Wenhui;Gu Chundong
8 一种用于非接触型细胞共培养的培养皿 专利 顾春东;赵士磊;郭涛;李逢州
9 MicroRNA-30e inhibits proliferation and invasion of non-small cell lung cancer via targeting SOX9 期刊论文 Cui Yanwei;Zhao Lei;Zhao Shilei;Guo Tao;Li Fengzhou;Li Zhuoshi;Fang Lei;Wu Taihua;Gu Chundong
10 GDF-15: A Multifunctional Modulator and Potential Therapeutic Target in Cancer 期刊论文 Fang Lei;Li Fengzhou;Gu Chundong
11 MicroRNA-30e Inhibits Cell Proliferation and Invasion in Non-Small Cell Lung Cancer via Directly Targeting SOX9 会议论文 L. Zhao;Z. Shilei;C. Gu;Y. Zhang;Z. Sun
12 Huaier Aqueous Extract Induces Lung Adenocarcinoma Cell Apoptosis Through Excessive Activation Of MEK/ERK Signaling Pathway 会议论文 Z. Shilei;C. Gu;Z. Lei;F. Zhou;J. Wang
13 Functional role of RBM10 in lung adenocarcinoma proliferation. 期刊论文 Sun Xiuna;Jia Mengqi;Sun Wei;Feng Lu;Gu Chundong;Wu Taihua
14 Elevated MACC1 expression predicts poor prognosis in small invasive lung adenocarcinoma. 期刊论文 Guo Tao;Zhao Shilei;Li Zhuoshi;Li Fengzhou;Li Jinxiu;Gu Chundong
15 YBX1 enhances metastasis and stemness by transcriptionally regulating MUC1 in lung adenocarcinoma 期刊论文 Qiang Xie;Shilei Zhao;Wenzhi Liu;Yanwei Cui;Fengzhou Li;Zhuoshi Li;Tao Guo;Wendan Yu;Wei Guo;Wuguo Deng;Chundong Gu
16 α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC) 期刊论文 Fengzhou Li;shilei zhao;Yanwei Cui;Tao Guo;jiaqi Qiang;Qiang Xie;Wendan Yu;Wei Guo;Wuguo Deng;Chundong Gu;Taihua Wu
17 YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC 期刊论文 Yanwei Cui;Fengzhou Li;Qiang Xie;Shilei Zhao;Tao Guo;Ping Guo;Sheng Hu;Jiaojiao Hao;Chunfang Tian;Wendan Yu;Zhuoshi Li;Lei Fang;Manyu Chen;Taihua Wu;Chundong Gu
18 肿瘤异质性基础及其潜在治疗方式选择 期刊论文 赵士磊;李逢洲;郭涛;顾春东
19 Genomic heterogeneity and clonality analysis of multiple synchronous lung cancers (MSLCs) 会议论文 F. Zhou;C. Gu;J. Wang;Y. Zhang;P. Wang;C. Lv;D. Bi;L. Zhao;Y. Zhu
20 Detection of Mediastinal Lymph Node Metastases Using Indocyanine Green (ICG) Fluorescence Imaging in an Orthotopic Implantation Model 期刊论文 Shilei Zhao;Xin Guo;Makoto Taniguchi;Kazuya Kondo;Sohsuke Yamada;Chundong Gu;Hidetaka Uramoto
21 GalNAc‑T3 and MUC1, a combined predictor of prognosis and recurrence in solitary pulmonary adenocarcinoma initially diagnosed as malignant solitary pulmonary nodule (≤3 cm) 期刊论文 Qiang Xie;Fengzhou Li;Shilei Zhao;Tao Guo;Zhuoshi Li;Lei Fang;Shiqing Wang;Wenzhi Liu;Chundong Gu
22 多原发肺癌外科诊疗策略进展 期刊论文 张翼翔;谢强;顾春东
23 周围型小肺癌诊疗问题 期刊论文 顾春东
24 肺癌转移新机制的临床和基础研究 奖励 顾春东;张晓辉;赵士磊;郭涛;李锦绣;李逢洲;王金
25 MACC1 overexpression in carcinoma-associated fibroblasts induces the invasion of lung adenocarcinoma cells via paracrine signaling 期刊论文 Li Zhuoshi;Guo Tao;Fang Lei;Li Nan;Wang Xiaochao;Wang Peng;Zhao Shilei;Li Fengzhou;Cui Yanwei;Shu Xin;Zhao Lei;Li Jinxiu;Gu Chundong
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