木犀草素抑制Nox4/ROS-NF-κB通路抗动脉粥样硬化作用及分子药理学机制研究

81273508
2012
H3502.心脑血管药物药理
孙慧君
面上项目
教授
大连医科大学
70万元
氧化;木犀草素;动脉粥样硬化;Nox4/ROS-NF-κB
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines 期刊论文 Changyuan Wang|Kexin Liu|Huijun Sun|Mozhen Liu|
2 Luteolin Protects HUVECs from TNF-alpha-induced Oxidative Stress and Inflammation via its Effects on the Nox4/ROS-NF-kappa B and MAPK Pathways 期刊论文 Qi Liu|Qiang Meng|Kexin Liu|Huijun Sun|
3 Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-α-induced VCAM-1, ICAM-1and EL expression via the NF-κB pathway 期刊论文 Yue Jin|Kexin Liu|Huijun Sun|Jianhua Qin|
4 Naringin inhibits TNF-alpha induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-kappa B and PI3K/Akt pathways. 期刊论文 Qi Liu|Qiang Meng|Kexin Liu|Huijun Sun|
5 Pharmacokinetics of phosphocreatine and its active metabolite creatine in the mouse plasma and myocardium 期刊论文 Lv, Li|Liu, Ke-Xin|Sun, Hui-Jun|Han, Guo-Zhu|
6 熊果酸抑制HepG2中C-反应蛋白的异常表达及其对HUVECs的损伤 期刊论文 王长远|刘 琦|孟 强|孙慧君|
7 Alpha-Lipoic Acid Promotes Osteoblastic Formation in H O -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats. 期刊论文 Qiang Meng|Kexin Liu|Huijun Sun|Mozhen Liu|
8 a-Lipoic acid protects HAECs from high glucose-induced apoptosis via decreased oxidative stress,ER stress and mitochondrial injury 期刊论文 Qi Liu|Qiang Meng|Kexin Liu|Huijun Sun|
9 薯蓣皂苷通过上调Lrp5、β-catenin表达促进成骨细胞MC3T3-E1增殖、分化 期刊论文 刘琦|孟强|刘克辛|孙慧君|
10 Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS–NF-κB signal pathway 期刊论文 Changyuan Wang|Li Kang|Ning Chang|Huijun Sun|
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