冠状病毒RNA加帽酶抑制剂的筛选及抑制机制研究
81271817
2012
H2101.呼吸道病毒与感染
陈宇
面上项目
教授
武汉大学
70万元
甲基转移酶;RNA加帽;冠状病毒;抑制剂
2013-01-01到2016-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase | 期刊论文 | Kaimei Wang|Liqiao Shi|Yu Chen|Deyin Guo| |
| 2 | Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis. | 期刊论文 | Shi, Zhengli|Ahola, Tero|Chen, Yu|Guo, Deyin| |
| 3 | The DEAD-Box RNA Helicase DDX3 Interacts with NF-kappa B Subunit p65 and Suppresses p65-Mediated Transcription | 期刊论文 | Sun, Guihong|Liu, Dan|Guo, Deyin|Chen, Yu| |
| 4 | Molecular mechanisms of coronavirus RNA capping and methylation | 期刊论文 | Chen, Yu|Guo, Deyin| |
| 5 | Prediction and biochemical analysis of putative cleavage sites of the 3C-like protease of Middle East respiratory syndrome coronavirus. | 期刊论文 | Su, Ceyang|Wang, Min|Chen, Yu|Guo, Deyin| |
| 6 | Prediction and biochemical analysis of putative cleavage sites of the 3C-like protease of Middle East respiratory syndrome coronavirus. | 期刊论文 | Su, Ceyang|Wang, Min|Chen, Yu|Guo, Deyin| |
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