人工化学合成-核磁共振联用技术研究翻译后修饰核小体的动态结构-功能关系

U1732161
2017
A3205.稳态强磁场
郑基深
联合基金项目
教授
中国科学技术大学
60万元
蛋白质化学合成;结构-功能研究;翻译后修饰;核磁共振技术;核小体
2018-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Thiirane linkers directed histone H2A diubiquitination suggests plasticity in 53BP1 recognition 期刊论文 Liang Jun;Gong Qingyue;Li Ying;Zheng Yong;Zheng Ji Shen;Tian Changlin;Li Jia Bin
2 Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy. 期刊论文 Qu Qian;Gao Shuai;Wu Fangming;Zhang Meng-Ge;Li Ying;Zhang Long-Hua;Bierer Donald;Tian Chang-Lin;Zheng Ji-Shen;Liu Lei
3 Chemical protein synthesis-assisted high-throughput screening strategies for d-peptides in drug discovery 期刊论文 Ying Li;Xiuxiu Cao;Changlin Tian;Ji-shen Zheng
4 The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis 期刊论文 Huang Dong-Liang;Li Ying;Liang Jun;Yu Lu;Xue Min;Cao Xiu-Xiu;Xiao Bin;Tian Chang-Lin;Liu Lei;Zheng Ji-Shen
5 Total chemical synthesis of bivalently modified H3 by improved three-segment native chemical ligation 期刊论文 Zheng Yong;Wu Fangming;Ling Shenglong;Li Jia-Bin;Tian Changlin
6 One-pot ligation strategy for atypical ubiquitin chains synthesis by using the trifluoroacetamidomethyl-protected isopeptide-linked Ub (Tfacm-isoUb) unit 期刊论文 Si Yan Yan;Liang Lu Jun;Tang Shan;Qi Yun Kun;Huang Yong;Zheng Ji Shen
7 One-pot multi-segment condensation strategies for chemical protein synthesis 期刊论文 Zuo Chong;Zhang Baochang;Yan Bingjia;Zheng Ji Shen
8 Recent advances in the chemical synthesis and semi-synthesis of poly-ubiquitin-based proteins and probes 期刊论文 Qi Yun Kun;Si Yan Yan;Du Shan Shan;Liang Jun;Wang Ke Wei;Zheng Ji Shen
9 Chemical Synthesis of Native S-Palmitoylated Membrane Proteins through Removable-Backbone-Modification-Assisted Ser/Thr Ligation. 期刊论文 Huang Dong-Liang;Montigny Cedric;Zheng Yong;Beswick Veronica;Li Ying;Cao Xiu-Xiu;Barbot Thomas;Jaxel Christine;Liang Jun;Xue Min;Tian Chang-Lin;Jamin Nadege;Zheng Ji-Shen
10 赖氨酸翻译后修饰蛋白质的化学(半)合成及其应用 期刊论文 王志鹏;李曼;李珲;刘志华;李影;郑基深
11 Channel activity of mirror-image M2 proton channel of influenza A virus is blocked by achiral or chiral inhibitors 期刊论文 Guo Qing Yan;Zhang Long Hua;Zuo Chao;Huang Dong Liang;Wang Zhipeng A;Zheng Ji Shen;Tian Chang Lin
12 Biochemical properties of K-11,K-48-branched ubiquitin chains 期刊论文 Liang Lu Jun;Si Yanyan;Tang Shan;Huang Dongliang;Wang Zhipeng A;Tian Changlin;Zheng Ji Shen
13 Reductive Amination/Alkylation Reactions: The Recent Developments, Progresses, and Applications in Protein Chemical Biology Studies 期刊论文 Wang Zhipeng A;Liang Yan Yu;Zheng Ji Shen
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