天然免疫抑制受体介导的非可控性肝炎恶性转化机制与免疫干预靶点研究

91429303
2014
H1102.免疫应答异常
田志刚
重大研究计划
教授
中国科学技术大学
350万元
肝细胞癌;肿瘤免疫逃逸;免疫抑制性受体;非可控性肝脏炎症;肿瘤免疫治疗
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer 期刊论文 Li R Fang F Jiang M Wang C Ma J Kang W Zhang
2 Interferon-γ facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance 期刊论文 Zeng Z;Li L;Chen Y;Wei H;Sun R;Tian Z
3 Themicrobiota maintain homeostasis of liver-resident γδT-17 cells in a lipidantigen/CD1d-dependent manner 期刊论文 Li F Hao X Chen Y Bai L Gao X Lian Z Wei H
4 Generation and Preclinical Characterization of an NKp80-Fc Fusion Protein for Redirected Cytolysis of Natural Killer (NK) Cells against Leukemia 期刊论文 Deng G;Zheng X;Zhou J;Wei H;Tian Z;Sun R
5 Targeting LUNX Inhibits Non-Small Cell Lung Cancer Growth and Metastasis 期刊论文 Zheng X;Cheng M;Fu B;Fan X;Wang Q;Yu X;Sun R
6 Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice 期刊论文 Cui K;Yan G;Xu C;Chen Y;Wang J;Zhou R;Bai L
7 NK cell subsets in autoimmune diseases 期刊论文 Zhang C Tian Z
8 The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore 期刊论文 Sun C;Xu J;Song J;Liu CQ;Wang J;Weng C;Sun
9 CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in HBsAg transgenic mice by promoting the interaction of NKT cells with Kupffer cells 期刊论文 Hou X Hao X Zheng M Xu C Wang J Zhou R Tian Z
10 Elimination of N-glycosylation by site mutation further prolongs the half-life of IFN-α/Fc fusion proteins expressed in Pichia pastoris 期刊论文 Jia H;Guo Y;Song X;Shao C;Wu J;Ma J;Shi M
11 The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education 期刊论文 Chen S;Yang M;Du J;Li D;Li Z;Cai C;Ma Y;Zha
12 Technical Improvement and Application of Hydrodynamic Gene Delivery in Study of Liver Diseases 期刊论文 Huang M Sun R Huang Q Tian Z
13 Tumor therapeutics work as stress inducers to enhance tumor sensitivity to NK cell cytolysis by upregulating NKp30 ligand B7-H6 期刊论文 Cao G;Wang J;Zheng X;Wei H;Tian Z;Sun R
14 NK Cell Exhaustion 期刊论文 Bi J Tian Z
15 Chronic Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis via Immune Disturbances 期刊论文 Yan G Wang X Sun C Zheng X Wei H Tian Z Sun
16 NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation 期刊论文 Yang M;Chen S;Du J;He J;Wang Y;Li Z;Liu G;P
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