从能量感受器AMPK揭示CR模拟剂限制失控性炎症反应的转录及翻译调控机制

81671953
2016
H1601.脓毒症
张力
面上项目
教授
重庆医科大学
57万元
炎症反应;能量代谢;热量限制模拟剂;腺苷酸活化蛋白激酶;能量感受器
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Endogenous AMPK acts as a detrimental factor in fulminant hepatitis via potentiating JNK-dependent hepatocyte apoptosis 期刊论文 Hu Kai;Gong Xianqiong;Ai Qing;Lin Ling;Dai Jie;Cai Lu;Jiang Rong;Ge Pu;Zhang Li
2 Lipopolysaccharide-Induced Dephosphorylation of AMPK-Activated Protein Kinase Potentiates Inflammatory Injury via Repression of ULK1-Dependent Autophagy 期刊论文 Fan Kerui;Lin Ling;Ai Qing;Wan Jingyuan;Dai Jie;Liu Gang;Tang Li;Yang Yongqiang;Ge Pu;Jiang Rong;Zhang Li
3 Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR 期刊论文 Wu Kejia;Tian Rui;Huang Jing;Yang Yongqiang;Dai Jie;Jiang Rong;Zhang Li
4 Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury Via Suppressing Nuclear Pyruvate Kinase M2-Signal Transducer and Activator of Transcription 3 Pathway 期刊论文 Hu Kai;Yang Yongqiang;Lin Ling;Ai Qing;Dai Jie;Fan Kerui;Ge Pu;Jiang Rong;Wan Jingyuan;Zhang Li
5 The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia 期刊论文 Huang Jing;Tian Rui;Yang Yongqiang;Jiang Rong;Dai Jie;Tang Li;Zhang Li
6 Protective benefits of AMP-activated protein kinase in hepatic ischemia-reperfusion injury 期刊论文 Zhang Min;Yang Dan;Gong Xianqiong;Ge Pu;Dai Jie;Lin Ling;Zhang Li
7 AMPK激活剂抗炎保护效应研究进展 期刊论文 彭先稳;周虹宏;代洁;张力
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