Curcumin调控分子马达促进自噬体轴突转运以减轻AD自噬应激的分子机制

81671261
2016
H0912.神经退行性变及相关疾病
李昱
面上项目
教授
重庆医科大学
59万元
阿尔茨海默病;自噬;姜黄素;轴突转运
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves A beta clearance and cognitive function in APP/PS1 double transgenic mice 期刊论文 Zhou Fanlin;Xiong Xiaomin;Li Shijie;Liang Jie;Zhang Xiong;Tian Mingyuan;Li Xiaoju;Gao Minna;Tang Li;Li Yu
2 姜黄素改善N2a/APP695swe细胞线粒体功能和抑制细胞凋亡的作用 期刊论文 梁洁;康清梅;张雄;周凡琳;高敏娜;李昱
3 Curcumin improves autophagy in N2a/APP695swe cells via elevating the expressions of Rab GTPases 会议论文 周凡琳;李昱
4 Study on congnitive impairment and differential metabolites of APP/PS1 double transgenic mice in different age groups 会议论文 李世杰;李昱
5 Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells 会议论文 周凡琳;李昱
6 姜黄素通过下调VEGF的表达抑制髓母细胞瘤Daoy细胞增殖的作用研究 期刊论文 高敏娜;张雄;康清梅;梁洁;李昱
7 Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells 期刊论文 Jie Liang;Fanlin Zhou;Xiaomin Xiong;Xiong Zhang;Shijie Li;Xiaoju Li;Minna Gao;Yu Li
8 姜黄素通过提高Rab家族蛋白的表达增强N2a/APP695swe细胞的自噬作用 期刊论文 周凡琳;熊晓敏;梁洁;张雄;李世杰;高敏娜;李昱
9 Curcumin Ameliorates Memory Deficits by Enhancing Lactate Content and MCT2 Expression in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease 期刊论文 Lu Wei Tian;Sun Shan Quan;Li Yu;Xu Shi Ye;Gan Sheng Wei;Xu Jin;Qiu Guo Ping;Zhuo Fei;Huang Si Qin;Jiang Xu Li;Huang Juan
10 Valinomycin reduces amyloid β peptide (A β by activating pink1/parkin in N2a/695swe cells 会议论文 熊晓敏;李昱
11 Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease 期刊论文 Xiaomin Xiong;Shijie Li;Ting-Li Han;Fanlin Zhou;Xiong Zhang;Mingyuan Tian;Li Tang;Yu Li
12 Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation 期刊论文 Zhou Jian;Yu Weihua;Zhang Man;Tian Xin;Li Yu;Lu Yang
13 姜黄素通过提高自噬体形成相关蛋白的表达增强N2a/APP695swe细胞的自噬作用 期刊论文 康清梅;梁洁;张雄;周凡琳;李丹;高敏娜;李昱
14 Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells 会议论文 周凡琳;李昱
15 Neuroprotection of Neuroprotectin D1 via Gsk-3β in Alzheimer‘s disease 会议论文 周凡琳;戴颂阳;李昱
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