PCK1通过Wnt信号通路抑制肝细胞癌的作用机制研究
81602417
2016
H1807.肿瘤代谢
汪凯
青年科学基金项目
副研究员
重庆医科大学
17万元
肿瘤抑制基因;Wnt信号通路;C09_肝和肝内胆管肿瘤;磷酸烯醇式丙酮酸羧激酶1
2017-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. | 期刊论文 | Jingjing Li;Qiujie Wang;Yi Yang;Chong Lei;Fan Yang;Li Liang;Chang Chen;Jie Xia;Kai Wang;Ni Tang |
| 2 | GSTZ1‐1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone | 期刊论文 | Yang Fan;Li Jingjing;Deng Haijun;Wang Yihao;Lei Chong;Wang Qiujie;Xiang Jin;Liang Li;Xia Jie;Pan Xuanming;Li Xiaosong;Long Quanxin;Chang Lei;Xu Ping;Huang Ailong;Wang Kai;Tang Ni |
| 3 | PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27(Kip1) axis. | 期刊论文 | Tuo Lin;Xiang Jin;Pan Xuanming;Hu Jieli;Tang Hua;Liang Li;Xia Jie;Hu Yuan;Zhang Wenlu;Huang Ailong;Wang Kai;Tang Ni |
| 4 | 果糖-1,6-二磷酸酶1抑制肝癌细胞株HepG2的自噬及增殖 | 期刊论文 | 潘璇明;张桂冀;陈雪梅;梁利;唐霓;汪凯 |
| 5 | GSTZ1-1 downregulates Wnt/beta-catenin signalling in hepatocellular carcinoma cells. | 期刊论文 | Chong Lei;Qiujie Wang;Ni Tang;Kai Wang |
| 6 | Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq | 期刊论文 | Jin Xiang;Yuhong Zhang;Lin Tuo;Rui Liu;Dongmei Gou;Li Liang;Chang Chen;Jie Xia;Ni Tang;Kai Wang |
| 7 | SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. | 期刊论文 | Gao Qingzhu;Zhang Guiji;Zheng Yaqiu;Yang Yi;Chen Chang;Xia Jie;Liang Li;Lei Chong;Hu Yuan;Cai Xuefei;Zhang Wenlu;Tang Hua;Chen Yaxi;Huang Ailong;Wang Kai;Tang Ni |
| 8 | PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway | 期刊论文 | Lin Tuo;Jin Xiang;Xuanming Pan;Qingzhu Gao;Guiji Zhang;Yi Yang;Li Liang;Jie Xia;Kai Wang;Ni Tang |
| 9 | PCK1影响肝癌细胞迁移能力的研究 | 期刊论文 | 向进;庹琳;高庆祝;杨翼;梁利;夏杰;唐霓;汪凯 |
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