棕榈酰化修饰对肝脏FAT/CD36蛋白定位和功能的影响及其在非酒精性脂肪性肝病发生中的作用机制研究

81570517
2015
H0307.肝脏代谢障碍及相关疾病
陈压西
面上项目
研究员
重庆医科大学
57万元
蛋白质棕榈酰化;亚细胞定位;非酒精性脂肪性肝病;脂肪酸转运酶
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis 期刊论文 Zhao Lei;Zhang Chang;Luo Xiaoxiao;Wang Pei;Zhou Wei;Zhong Shan;Xie Yunxia;Jiang Yibo;Yang Ping;Tang Renkuang;Pan Qin;Hall Andrew R;Tu Vinh Luong;Fan Jiangao;Varghese Zac;Moorhead John F;Pinzani Massimo;Chen Yaxi;Ruan Xiong Z
2 Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress 期刊论文 Liu Jun;Yang Ping;Zuo Guoqing;He Song;Tan Wei;Zhang Xiaoyu;Su Chunxiao;Zhao Lei;Wei Li;Chen Yao;Ruan Xiongzhong;Chen Yaxi
3 SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE(-/-) mice 期刊论文 Li Danyang;Chen Amei;Lan Tan;Zou Yang;Zhao Lei;Yang Ping;Qu Haiyang;Wei Li;Varghese Zac;Moorhead John F;Chen Yaxi;Ruan Xiong Z
4 CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway[S] 期刊论文 Li Yun;Yang Ping;Zhao Lei;Chen Yao;Zhang Xiaoyu;Zeng Shu;Wei Li;Varghese Zac;Moorhead John F;Chen Yaxi;Ruan Xiong Z
5 High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways 期刊论文 Zhang Xiaoyu;Yang Ping;Luo Xuan;Su Chunxiao;Chen Yao;Zhao Lei;Wei Li;Zeng Han;Varghese Zac;Moorhead John F;Ruan Xiong Z;Chen Yaxi
6 Fatty acid translocase promoted hepatitis B virus replication by upregulating the levels of hepatic cytosolic calcium 期刊论文 Huang Jian;Zhao Lei;Yang Ping;Chen Zhen;Ruan Xiong Z.;Huang Ailong;Tang Ni;Chen Yaxi
7 High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways 期刊论文 Zhang Xiaoyu;Yang Ping;Luo Xuan;Su Chunxiao;Chen Yao;Zhao Lei;Wei Li;Zeng Han;Varghese Zac;Moorhead John F;Ruan Xiong Z;Chen Yaxi
8 CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis 期刊论文 Zhao Lei;Zhang Chang;Luo Xiaoxiao;Wang Pei;Zhou Wei;Zhong Shan;Xie Yunxia;Jiang Yibo;Yang Ping;Tang Renkuang;Pan Qin;Hall Andrew R;Tu Vinh Luong;Fan Jiangao;Varghese Zac;Moorhead John F;Pinzani Massimo;Chen Yaxi;Ruan Xiong Z
9 Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells 期刊论文 Gao Huanqing;Li Danyang;Yang Ping;Zhao Lei;Wei Li;Chen Yaxi();Ruan Xiong Z.()
10 Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway 期刊论文 Zhong Shan();Zhao Lei();Wang Yan;Zhang Chang;Liu Jun;Wang Pei;Zhou Wei;Yang Ping;Varghese Zac;Moorhead John F.;Chen Yaxi();Ruan Xiong Z.()
11 Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway. 期刊论文 Yang Ping();Su Chunxiao();Luo Xuan();Zeng Han;Zhao Lei;Wei Li;Zhang Xiaoyu;Varghese Zac;Moorhead John F;Chen Yaxi();Ruan Xiong Z()
12 Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice. 期刊论文 Wu Wei;Zhao Lei;Yang Ping;Zhou Wei;Li Beibei;Moorhead John F;Varghese Zac;Ruan Xiong Z();Chen Yaxi()
13 CD36 and lipid metabolism in the evolution of atherosclerosis 期刊论文 Zhao Lei;Varghese Z;Moorhead J F;Chen Yaxi;Ruan Xiong Z()
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