生（干）姜及其主要活性成分改善非酒精性脂肪肝过程中对肝ChREBP的分子调控

81374033
2013
H3211.中药内分泌与代谢药理
王建伟
面上项目
教授
重庆医科大学
66万元
生（干）姜;蛋白质;碳水化合物反应元件结合蛋白;非酒精性脂肪肝;O位N－乙酰葡萄糖胺糖基化;蛋白质磷酸化
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ginger extract diminishes chronic fructose consumption-induced kidney injury through suppression of renal overexpression of proinflammatory cytokines in rats 期刊论文 Yang Ming;Liu Changjin;Jiang Jian;Zuo Guowei;Lin Xuemei;Yamahara Johji;Wang Jianwei;Li Yuhao
2 芒果苷改善高果糖所致自发性高血压大鼠肾间质纤维沉积的可能机制 期刊论文 周良;赵元阳;邢小忙;潘永全;姚玲;李春丽;姜蓉;林雪梅;王建伟
3 Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2 期刊论文 Zhao Yuanyang;Pan Yongquan;Yang Yifan;Batey Robert;Wang Jianwei;Li Yuhao
4 Mitigation of Insulin Resistance by Mangiferin in a Rat Model of Fructose-Induced Metabolic Syndrome Is Associated with Modulation of CD36 Redistribution in the Skeletal Muscle 期刊论文 Zhou Liang;Pan Yongquan;Chonan Ritsu;Batey Robert;Rong Xianglu;Yamahara Johji;Wang Jianwei;Li Yuhao
5 6-Gingerol improves ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle of aging rats: dual stimulation of AMPK/PGC-1α signaling pathway via plasma adiponectin and muscular AdipoR1 会议论文 Liu Li;Yao Ling;Wang Shang;Chen Zhiwei;Han Tingli;Ma Peng;Jiang Lirong;Li Jinxiu;Ke Dazhi;Li Chunli;Yamahara Johji;Li Yuhao;Wang Jianwei
6 Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A: diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to amelioration of fatty liver 期刊论文 Xing Xiaomang;Li Danyang;Chen Dilong;Zhou Liang;Chonan Ritsu;Yamahara Johji;Wang Jianwei;Li Yuhao
7 芒果苷改善高果糖所致HepG2细胞内甘油三酯沉积机制研究 期刊论文 郑旭;李丹阳;赵元阳;周良;曹文富;曹纬国;姚玲;王建伟
8 生姜乙醇提取物改善果糖所致大鼠脂肪肝的作用机制研究 期刊论文 陈婷;姚玲;柯大智;左国伟;曹纬国;王尚;马朋;蒋丽蓉;Johji Yamahara;Yuhao Li;王建伟
9 Response of genes involved in lipid metabolism in rat epididymal white adipose tissue to different fasting conditions after long-term fructose consumption 期刊论文 Li Jin-xiu;Ke Da-zhi;Yao Ling;Wang Shang;Ma Peng;Liu Li;Zuo Guo-wei;Jiang Li-rong;Wang Jian-wei
10 Long-term fructose consumption prolongs hepatic stearoyl-CoA desaturase 1 activity independent of upstream regulation in rats 期刊论文 Liu Li;Wang Shang;Yao Ling;Li Jin-xiu;Ma Peng;Jiang Li-rong;Ke Da-zhi;Pan Yong-quan;Wang Jian-wei
11 Jiangzhi Capsule improves fructose-induced insulin resistance in rats: Association with repair of the impaired sarcolemmal glucose transporter-4 recycling. 期刊论文 Jiang Lirong;Yao Ling;Yang Yifan;Ke Dazhi;Batey Robert;Wang Jianwei;Li Yuhao
12 A mixture of apple pomace and rosemary extract improves fructose consumption-induced insulin resistance in rats: modulation of sarcolemmal CD36 and glucose transporter-4 期刊论文 Ma Peng;Yao Ling;Lin Xuemei;Gu Tieguang;Rong Xianglu;Batey Robert;Yamahara Johji;Wang Jianwei;Li Yuhao
13 Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats 期刊论文 Li Ying;Wang Jianwei;Gu Tieguang;Yamahara Johji;Li Yuhao
14 不同果糖喂养状态下大鼠肝脏的内参基因稳定性分析 期刊论文 王尚;姚玲;马朋;蒋丽蓉;柯大智;刘丽;李金秀;姜蓉;王建伟
15 高果糖引起的脂肪肝大鼠肾脏脂质合成相关基因和蛋白的表达 期刊论文 刘长金;刘磊;柯大智;林雪梅;姜蓉;胥文春;左国伟;王建伟
16 6-Gingerol ameliorates age-related hepatic steatosis through regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction 会议论文 Li JinXiu;Wang Shang;Yao Ling;Ma Peng;Chen Zhiwei;Han Tingli;Liu Li;Ke Dazhi;Li Chunli;Yamahara Johji;Li Yuhao;Wang Jianwei
17 Treatment with Rhodiola crenulata root extract ameliorates insulin resistance in fructose-fed rats by modulating sarcolemmal and intracellular fatty acid translocase/CD36 redistribution in skeletal muscle 期刊论文 Chen Ting;Yao Ling;Ke Dazhi;Cao Weiguo;Zuo Guowei;Zhou Liang;Jiang Jian;Yamahara Johji;Li Yuhao;Wang Jianwei
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