从AhR、VitD3和miRNA对DC的调控探讨葡萄膜炎的发病机制及防治

81130019
2011
H1303.巩膜、葡萄膜、眼免疫
杨培增
重点项目
教授
重庆医科大学
280万元
葡萄膜炎;miRNA;维生素D3;发病机制;芳香烃受体
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 MIF gene polymorphisms confer susceptibility to Vogt-Koyanagi-Harada syndrome in a Han Chinese population. 期刊论文 Zheng, Xiuyun|Xiao, Xiang|Kijlstra, Aize|Yang, Peizeng|
2 Association of Macrophage Migration Inhibitory Factor Gene Polymorphisms with Behcet's Disease in a Han Chinese Population 期刊论文 B. Lei|X. Xiao|A. Kijlstra|P. Yang|
3 Association of ATG5 gene polymorphisms with Behcet's disease and ATG10 gene polymorphisms with VKH syndrome in a Chinese Han population. 期刊论文 Li H|Liu Y|Kijlstra A|Yang P|
4 Association of Genetic Variations in TNFSF15 With Acute Anterior Uveitis in Chinese Han. 期刊论文 Cao Q|Yuan G|Kijlstra A|Yang P|
5 Decreased IL-27 in association with an increased Th17 response in Vogt-Koyanagi-Harada disease. 期刊论文 Wang C, Tian Y, Ye Z, Kijlstra A, Xiao X, Zhou Y,|
6 Ocular manifestations of syphilitic uveitis in Chinese patients 期刊论文 Ni zhang|Fuzhen LI|Ying Chen|Aize Kijlstra|
7 A possible role for interleukin 37 in the pathogenesis of Behcet's disease. 期刊论文 Wang, C|Kijlstra, A|Zhou, X|Yang, P|
8 FoxO1 gene confers genetic predisposition to acute anterior uveitis with ankylosing spondylitis. 期刊论文 Cheng, Ling|Luo, Le|Kijlstra, Aize|Yang, Peizeng|
9 Interleukin-10 gene polymorphisms are associated with Behcet's disease but not with Vogt-Koyanagi-Harada syndrome in Chinese Han population. 期刊论文 Liu Y|Bai L|Kijlstra A|Yang P|
10 Effect of 1,25-dihydroxyvitamin D3 on Th17 and Th1 response in patients with Behcet's disease. 期刊论文 Ye, Zi|Xiao, Xiang|Kijlstra, Aize|Yang, Peizeng|
11 Replication study confirms the association between UBAC2 and Beh?et’s disease in two independent Chinese sets of patients and controls. 期刊论文 Hou S, Shu Q, Jiang Z, Chen Y, Li F, Chen F, Kijl|
12 Two-stage association study identifies three associated variants in CCR1 gene for Beh?et’s disease in Chinese Han. 期刊论文 Hou S, Xiao X, Li F, Jiang Z, Kijlstra A, Yang Pe|
13 Inhibition of pro-inflammatory 1 cytokine by IL-25 in Vogt-Koyanagi-Harada syndrome. 期刊论文 Wang C|Tian Y|Kijlstra A|Yang P|
14 Lack of association of miR-146a and Ets-1 gene polymorphisms with Fuchs uveitis syndrome in Chinese Han patients 期刊论文 X. Zhang|X. Li|X. Xiao|P. Yang|
15 Genetic variants in the JAK1 gene confer higher risk of Behcet's disease with ocular involvement in Han Chinese. 期刊论文 Hu, Ke|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
16 No association between Bach2 gene polymorphisms with Vogt–Koyanagi–Harada syndrome (VKH) and Q1 Behcet’s disease (BD) in a Chinese Han population. 期刊论文 Lv S|Hou S|Kijlstra A|Yang P|
17 Decreased microRNA-155 expression in ocular Behcet's disease but not in Vogt Koyanagi Harada syndrome 期刊论文 杨培增|
18 TNF receptor-associated factor 5 gene confers genetic predisposition to acute anterior uveitis and pediatric uveitis. 期刊论文 Liu, Yunjia|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
19 High C4 Gene Copy Numbers Protects against Susceptibility to Vogt-Koyanagi-Harada syndrome in Chinese Han. 期刊论文 Fang J|Chen L|Kijlstra A|Yang P|
20 High-salt enhances the inflammatory response by RPE cells following LPS stimulation 期刊论文 Ye Z|Deng B|Kijlstra A|Yang P|
21 Decreased expression of the aryl hydrocarbon receptor in ocular Behcet’s disease. 期刊论文 Ye Z|Kijlstra A|Zhou Y|Yang P|
22 Copy Number Variations of C4 are associated with Behcet's disease but not with Ankylosing spondylitis associated with Acute anterior uveitis. 期刊论文 Bai L|Zhang M|Kijlstra A|Yang P|
23 TLR3 and TLR4 But not TLR2 are Involved in Vogt-Koyanagi-Harada Disease by Triggering Proinflammatory Cytokines Production Through Promoting the Production of Mitochondrial Reactive Oxygen Species 期刊论文 Zhu Y|Tian Y|Kijlstra A|Yang P|
24 FAS gene copy numbers are associated with susceptibility to Beh?et’s disease and VKH syndrome in Han Chinese. 期刊论文 Yu H, Luo L, Wu L, Zheng M, Zhang L, Liu Y, Li H,|
25 Complement C5 gene confers risk for acute anterior uveitis. 期刊论文 Zhang D|Luo L|Kijlstra A|Yang P|
26 MicroRNA-146a and Ets-1 gene polymorphisms in ocular Beh?et’s disease and Vogt–Koyanagi–Harada syndrome 期刊论文 Zhou Q, Hou S,Liang L, Li X, Tian X, Wei L,Lei B,|
27 Decreased Interleukin-27 Expression is Associated with Active Uveitis in Behcet’s Disease. 期刊论文 Wang C, Tian Y, Ye Z, Kijlstra A, Zhou Y, Yang Pe|
28 TNFAIP3 gene polymorphisms in a Chinese Han population with Vogt-Koyanagi-Harada syndrome. 期刊论文 Zhou, Qingyun|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
29 Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population. 期刊论文 Qi, Jian|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
30 Investigation of the Association of Vogt-Koyanagi-Harada Syndrome with IL23R-C1orf141 in Han Chinese Singaporean and ADO-ZNF365-EGR2 in Thai 期刊论文 Hou S|Wu L|Kijlstra A|Yang P|
31 Genetic Variations of IL17F and IL23A Show Associations with Beh?et’s Disease and Vogt-Koyanagi-Harada Syndrome. 期刊论文 Hou S, Liao D, Zhang J, Fang J, Chen L, Qi J, Zha|
32 IL-1β triggered by Peptidoglycan and lipopolysaccharide through TLR2/4 and ROS-NLRP3 inflammasome dependent pathways is involved in ocular Behcet's disease. 期刊论文 Liang L, Tan X, Zhou Q, Zhu Y, Tian Y, Yu H, Kijl|
33 Vogt-Koyanagi-Harada disease: Novel insights into pathophysiology, diagnosis and treatment 期刊论文 Du, Liping|Kijlstra, Aize|Yang, Peizeng|
34 Decreased Interleukin-37 Expression in Vogt-Koyanagi-Harada Disease and Upregulation Following Immunosuppressive Treatment. 期刊论文 Bai, Lin|Liu, Yunjia|Kijlstra, Aize|Yang, Peizeng|
35 Increased IL-7 expression in Vogt-Koyanagi-Harada disease 期刊论文 杨培增|
36 Increased Notch pathway activation in Behcet's disease. 期刊论文 Zhang, Qi|Cai, Tao|Kijlstra, Aize|Yang, Peizeng|
37 Effect of berberine on proinflammatory cytokine production by ARPE-19 cells following stimulation with tumor necrosis factor-alpha 期刊论文 杨培增|
38 Association between Copy Number Variation of TLR7 and Ocular Behcet's disease in a Chinese Han Population. 期刊论文 Wang C|Cao Q|Kijlstra A|Yang P|
39 Predisposition to Beh?et's disease and VKH syndrome by genetic variants of miR-182. 期刊论文 Liu Y|Bai L|Kijlstra A|Yang P|
40 Berberine suppresses Th17 and dendritic cell responses. 期刊论文 Zhou, Yan|Yu, Hongsong|Kijlstra, Aize|Yang, Peizeng|
41 JAK1, but not JAK2 and STAT3, confers susceptibility to Vogt-Koyanagi-Harada (VKH) syndrome in a Han Chinese population. 期刊论文 Li, Fuzhen|Xiang, Qin|Kijlstra, Aize|Yang, Peizeng|
42 Identification of a Susceptibility Locus in STAT4 for Behcet’s Disease in Han Chinese in a Genome-Wide Association Study. 期刊论文 Hou S, Yang Z, Du L, Jiang Z, Shu Q, Chen Y, Li F|
43 Polymorphisms in genetics of Vitamin D metabolism confer susceptibility to ocular Behcet's disease in a Chinese Han population. 期刊论文 Fang J, Hou S, Xiang Q, Qi J, Yu H, Shi Y, Zhou Y|
44 Association of ERAP1 gene polymorphisms with Beh?et's disease in Han Chinese. 期刊论文 Li H|Liu Y|Kijlstra A|Yang P|
45 Higher expressionof NOD1 and NOD2 is associated with Vogt-Koyanagi-Harada(VKH) syndrome but not Behcet’s disease (BD) 期刊论文 Lin Li|Yue He|Chaokui Wang|peizeng Yang|
46 Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3. 期刊论文 Kijlstra, Aize|Xu, Jianfeng|Yang, Zhenglin|Yang, Peizeng|
47 Higher expression of Toll-like receptors 2, 3, 4 and 8 in ocular Behcet's disease. 期刊论文 Liu X, Wang C, Kijlstra A,Yang Peizeng|
48 Genetic Variant on PDGFRL Associated with Behcet Disease in Chinese Han Populations 期刊论文 X. Zhu|F. Li|A. Kijlstra|P. Yang|
49 MicroRNA-146a and Ets-1 gene polymorphisms are associated with pediatric uveitis. 期刊论文 Xiang, Qin|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
50 miR-23a, miR-146a and miR-301a confer predisposition to Vogt-Koyanagi-Harada syndrome but not to Behcet's disease 期刊论文 Liu Y|Zhang J|Kijlstra A|Yang P|
51 TNFAIP3 gene polymorphisms confer risk for Behcet’s disease in a Chinese Hanpopulation 期刊论文 Hong LI|Qing Liu|Shengping Hou|Peizeng Yang|
52 Identification of twonovel susceptibility SNPs in IL10 and IL23R-IL12RB2 for Beh?et's disease in HanChinese 期刊论文 Hongsong Yu|mingmin zheng|lijun zhang|peizeng Yang|
53 Sphingosine 1-phosphate elicits proinflammatory responses in ARPE-19 cells. 期刊论文 Qi, Jian|Yang, Yan|Kijlstra, Aize|Yang, Peizeng|
54 Decreased B and T lymphocyte attenuator in Behcet's disease may trigger abnormal Th17 and Th1 immune responses 期刊论文 Wang, Chaokui|Zhang, Dike|Kijlstra, Aize|Yang, Peizeng|
55 A functional variant of pre-miRNA-196a2 confers risk for Behcet's disease but not for Vogt-Koyanagi-Harada syndrome or AAU in ankylosing spondylitis. 期刊论文 Fang, Jing|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
56 Activation of the Liver X Receptor Inhibits Th17 and Th1 Responses in Behcet’s Disease and Vogt-Koyanagi-Harada Disease. 期刊论文 Liu Y|Bai L|Kijlstra A|Yang P|
57 Male gender, erythema nodosum and ERG predict visualprognosis following cataract surgery in patients with Behcet's disease 期刊论文 Ke Hu|Bo Lei|PingHua Li|Peizeng Yang|
58 Activation of the aryl hydrocarbon receptor affects activation and function of human monocyte-derived dendritic cells. 期刊论文 Ye, Z|Kijlstra, A|Zhou, Y|Yang, P|
59 A variant of CLEC16A gene confers protection for Vogt-Koyanagi-Harada syndrome but not for Behcet's disease in a Chinese Han population. 期刊论文 Hou S|Qi J|Kijlstra A|Yang P|
60 Genetic variants in the JAK1 gene confer higher risk of Behcet's disease with ocular involvement in Han Chinese. 期刊论文 Hu, Ke|Zhou, Yan|Kijlstra, Aize|Yang, Peizeng|
61 Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3. 期刊论文 Kijlstra, Aize|Xu, Jianfeng|Yang, Zhenglin|Yang, Peizeng|
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