【30830106】提高骨髓间充质干细胞治疗缺氧缺血性脑损伤疗效及开关机制国家自然基金项目

提高骨髓间充质干细胞治疗缺氧缺血性脑损伤疗效及开关机制

项目批准号： 30830106

批准年份： 2008

学科分类： H0906.脑血管结构、功能异常及相关疾病

项目负责人：李廷玉

资助类别：重点项目

负责人职称：教授

依托单位：重庆医科大学

资助金额： 170万元

关键词：缺氧缺血性脑损伤;骨髓间充质干细胞;视黄酸;神经分化

起止时间： 2009-01-01到2012-12-31

中英文摘要
结题摘要
结题报告
项目成果
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序号	标题	类型	作者
1	Mechanisms of Hippocampal Long-Term Depression Are Required for Memory Enhancement by Novelty Exploration	期刊论文	Dong ZF\|Dong ZF\|Gong B\|Gong B\|Li HJ\|Li HJ\|Bai YR\|Bai YR\|Wu XY\|Wu XY\|Huang Y\|Huang Y\|He WT\|He WT\|Li TY\|Li TY\|Wang YT\|Wang YT\|
2	Switching from bone marrow-derived neurons to epithelial cells through dedifferentiation and translineage redifferentiation	期刊论文	Liu, Yang\|Jiang, Xiaohua\|Yu, Mei Kuen\|Dong, Jianda\|Zhang, Xiaohu\|Tsang, Lai Ling\|Chung, Yiu Wa\|Li, Tingyu\|Chan, Hsiao Chang\|
3	The pattern of retinoic acid receptor expression and subcellular, anatomic and functional area translocation during the postnatal development of the rat cerebral cortex and white matter	期刊论文	Jiang W\|Qu P\|Liu YX\|Wei XP\|Li TY\|Wen EY\|Gong M\|Shi Y\|Chen L\|Bi Y\|Zhang Y\|Liu YF\|Chen J\|
4	沉默视黄酸受体a损伤大鼠原代海马神经元的钙兴奋性	期刊论文	江伟\|陈洁\|李廷玉\|喻琴\|龚敏\|毕杨\|张赟\|陈立\|瞿平\|魏小平\|刘友学\|
5	Vitamin A deficiency impairs postnatal cognitive function via inhibition of neurinal calcium excitability in hippocampus	期刊论文	Jiang W\|LIu YX\|Wei XP\|Chen J\|Li TY\|Yu Q\|Gong M\|Chen L\|Wen EY\|Bi Y\|Zhang Y\|Shi Y\|Qu P\|
6	Effect of biscuits fortified with different doses of vitamin A on indices of vitamin A status, haemoglobin and physical growth levels of pre-school children in Chongqing	期刊论文	Zhang, Xuan\|Chen, Ke\|Qu, Ping\|Liu, You-Xue\|Li, Ting-Yu\|
7	视黄酸核受体RARa的siRNA重组腺病毒构建及干扰效果初步鉴定	期刊论文	龚敏\|毕杨\|张赟\|江伟\|陈洁\|李廷玉\|
8	Hippocampal long-term depression mediates spatial reversal learning in the Morris water maze	期刊论文	Huang Y\|He WT\|Li TY\|Wang YT\|
9	Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells	期刊论文	Bi, Yang\|Li, Tingyu\|Gong, Min\|Zhang, Xiaojuan\|Zhang, Xuan\|Jiang, Wei\|Zhang, Yun\|Chen, Jie\|Liu, Youxue\|He, Tong-Chuan\|
10	腺病毒介导siRNA抑制全反式维甲酸诱导的骨髓间充质干细胞RARb表达	期刊论文	毕杨\|龚敏\|何昀\|张赟\|陈洁\|李廷玉\|
11	AP2a重组腺病毒质粒的构建及其在大鼠骨髓间充质干细胞中的表达	期刊论文	毕杨\|龚敏\|何昀\|张赟\|陈洁\|李廷玉\|
12	视黄酸核受体r重组腺病毒构建及其鉴定	期刊论文	龚敏\|龚敏\|毕杨\|毕杨\|张赟\|张赟\|江伟\|江伟\|陈洁\|陈洁\|魏小平\|魏小平\|刘友学\|刘友学\|李廷玉\|李廷玉\|
13	体外诱导微环境对骨髓间充质干细胞成神经分化的影响及分化后的自发逆转现象	期刊论文	龚敏\|毕杨\|江伟\|张小娟\|张赟\|魏小平\|陈洁\|刘友学\|李廷玉\|
14	Mesenchymal stromal cell neuroprotection of hydrogen peroxidechallenged pheochromocytoma cells through reducing apoptosis and releasing cytokines	期刊论文	Zhang Y\|Yang Y\|Bi Y\|Gong M\|Jiang W\|Wei X\|Li T\|Chen J\|
15	Perinatal Vitamin A Status in Relation to Neurodevelopmental Outcome at two Years of Age	期刊论文	Zhang, Xuan\|Chen, Ke\|Wei, Xiao-Ping\|Qu, Ping\|Liu, You-Xue\|Chen, Jie\|Li, Ting-Yu\|
16	ATRA和9-cis-RA对缺氧缺糖损伤PC12细胞凋亡的影响	期刊论文	江伟\|李廷玉\|温恩懿\|龚敏\|瞿平\|毕杨\|张赟\|魏小平\|刘友学\|陈洁\|
17	Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential	期刊论文	Liu, Yang\|Ruan, Yechun\|Guo, Jinghui\|Yu, Mei Kuen\|Tian, Yuemin\|Chung, Yiu Wa\|Yang, Mo\|Xu, Wenming\|Chung, Chin Man\|Li, Tingyu\|Chan, Hsiao Chang\|Jiang, Xiaohua\|Zhang, Xiaohu\|Chen, Rui\|Sun, Tingting\|Fok, Kin Lam\|Dong, Jianda\|Tsang, Lai Ling\|Yi, Shaoqiong\|
18	Effect of marginal vitamin A deficiency during pregnancy on retinoic acid receptors and N-methyl-D-aspartate receptor expression in the offspring of rats	期刊论文	Zhang, Xuan\|Chen, Ke\|Chen, Jie\|Liu, You-xue\|Qu, Ping\|Li, Ting-yu\|
19	维生素A及相关因素对儿童早期生长发育的影响及干预研究	奖励	李廷玉\|毕杨\|黄鸿眉\|魏华\|赵勇\|陈科\|杨莉\|刘友学\|练雪梅\|陈洁\|张萱\|魏小平\|陈立\|江伟\|董志芳\|
20	人脐带间充质干细胞的分离鉴定及其修复缺血缺氧脑损伤作用	期刊论文	江伟\|李廷玉\|沈洁\|史源\|龚敏\|瞿平\|张赟\|魏小平\|刘友学\|陈洁\|
21	Immortalized mesenchymal stem cells: an alternative to primary mesenchymal stem cells in neuronal differentiation and neuroregeneration associated studies	期刊论文	Gong M\|Li T\|Bi Y\|Jiang W\|Zhang Y\|Chen L\|Hou N\|Liu Y\|Wei X\|Chen J\|
22	显性负性突变体对AP2a转录因子及其活性的影响	期刊论文	毕杨\|何昀\|龚敏\|张赟\|陈洁\|李廷玉\|

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