Foxp3介导孕期尼古丁暴露致子代调节性T细胞发育编程改变及哮喘易感的表观遗传机制

81673215
2016
H3007.卫生毒理
平洁
面上项目
教授
武汉大学
70万元
调节性T细胞;胸腺;哮喘;尼古丁;DNA甲基化
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Enhanced thymocyte apoptosis induced by maternal undernutrition in late gestation results in declined mature T cells in rat fetal thymus. 期刊论文 Wen Qu;Liang-Peng Ma;Hui-Yi Yan;Sha Liu;Han-Xiao Liu;Ting Chen;Li-Fang Hou;Jie Ping
2 Maternal Glucocorticoid Elevation and Associated Fetal Thymocyte Apoptosis Are Involved in Immune Disorders of Prenatal Caffeine Exposed Offspring Mice. 期刊论文 Han-xiao Liu;Ting Chen;Xiao Wen;Wen Qu;Sha Liu;Hui-yi Yan;Li-fang Hou;Jie Ping
3 Inhibition of thymocyte autophagy-associated CD4+T thymopoiesis is involved in asthma susceptibility in mice exposed to caffeine prenatally. 期刊论文 Han-Xiao Liu;Hui-Yi Yan;Wen Qu;Xiao Wen;Li-Fang Hou;Wen-Hao Zhao;Jie Ping
4 Prenatal Caffeine Ingestion Induces Long-Term Alterations in Scavenger Receptor Class B Type I Expression and Glucocorticoid Synthesis in Adult Male Offspring Rat Adrenals. 期刊论文 Dong-Mei Wu;Xiao Wen;Wen Qu;Han-Xiao Liu;Liang-Peng Ma;Ting Chen;Jie Ping
5 Intrauterine growth retardation-associated syncytin b hypermethylation in maternal rat blood revealed by DNA methylation array analysis 期刊论文 Dong-Mei Wu;You-E Yan;Liang-Peng Ma;Han-Xiao Liu;Wen Qu;Jie Ping
6 Attenuated cholesterol metabolism pathway suppresses regulatory T cell development in prenatal nicotine exposed female mice. 期刊论文 Xiao Wen;Wen-Hao Zhao;Lan-Zhou Chen;Wen Qu;Han-Xiao Liu;Hui-Yi Yan;Li-Fang Hou;Jie Ping
7 Attenuated Tregs increase susceptibility to type 1 diabetes in prenatal nicotine exposed female offspring mice. 期刊论文 Wen-Hao Zhao;Xiao Wen;Wen Qu;Han-Xiao Liu;Hui-Yi Yan;Li-Fang Hou;Jie Ping
8 Reproductive Toxicity of T Cells in Early Life: Abnormal Immune Development and Postnatal Diseases. 期刊论文 Han-Xiao Liu;Aifang Jiang;Ting Chen;Wen Qu;Hui-Yi Yan;Jie Ping
9 Prenatal nicotine exposure induces thymic hypoplasia in mice offspring from neonatal to adulthood. 期刊论文 Wen Qu;Wen-Hao Zhao;Xiao Wen;Hui-Yi Yan;Han-Xiao Liu;Li-Fang Hou;Jie Ping
10 Prenatal caffeine ingestion increases susceptibility to pulmonary inflammation in adult female rat offspring. 期刊论文 Han-Xiao Liu;Li-Fang Hou;Ting Chen;Wen Qu;Sha Liu;Hui-Yi Yan;Xiao Wen;Jie Ping
11 Augmented autophagy suppresses thymocytes development via Bcl10/p-p65 pathway in prenatal nicotine exposed fetal mice. 期刊论文 Hui-Yi Yan;Xiao Wen;Lan-Zhou Chen;Yi-Ting Feng;Han-Xiao Liu;Wen Qu;Wen-Hao Zhao;Dong-Qin Xu;Jie Ping
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