IRXs在心肌纤维化中的作用机制和干预研究
81530012
2015
H02.循环系统
唐其柱
重点项目
教授
武汉大学
274万元
2016-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Deficiency Attenuated Isoproterenol-Induced Cardiac Fibrosis via Reactive Oxygen Species/High Mobility Group Box 1 Protein Axis | 期刊论文 | Chen Liu;Tong-Tong Hu;Zhu-Lan Cai;Qing-Wen Xie;Yuan Yuan;Ning Li;Sai-Yang Xie;Qi Yao;Jin-Hua Zhao;Qing-Qing Wu;Qi-Zhu Tang |
| 2 | Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target | 期刊论文 | Heng Zhou;Ning Li;Yuan Yuan;Ya-Ge Jin;Hai-Peng Guo;Wei Deng;Qi-Zhu Tang |
| 3 | Deletion of Microfibrillar-Associated Protein 4 Attenuates Left Ventricular Remodeling and Dysfunction in Heart Failure | 期刊论文 | Hui-Bo Wang;Jian Yang;Wei Shuai;Jun Yang;Li-Bo Liu;Man Xu;Qi-Zhu Tang |
| 4 | Mechanisms contributing to cardiac remodelling | 期刊论文 | Qing-Qing Wu;Yang Xiao;Yuan Yuan;Zhen-Guo Ma;Hai Han Liao;Chen Liu;Jin-Xiu Zhu;Zheng Yang;Wei Deng;Qi-Zhu Tang |
| 5 | AdipoRon, an adiponectin receptor agonist, attenuates cardiac remodeling induced by pressure overload | 期刊论文 | Ning Zhang;Wen-Ying Wei;Hai-Han Liao;Zheng Yang;Can Hu;Sha-Sha Wang;Wei Deng;Qi-Zhu Tang |
| 6 | FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT | 期刊论文 | Xin Zhang;Can Hu;Chun-Yan Kong;Peng Song;Hai-Ming Wu;Si-Chi Xu;Yu-Pei Yuan;Wei Deng;Zhen-Guo Ma;Qi‑Zhu Tang |
| 7 | Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy | 期刊论文 | Man Xu;Chun-xia Wan;Si-hui Huang;Hui-Bo Wang;Di Fan;Hai-Ming Wu;Qing-Qing Wu;Zhen-Guo Ma;Wei Deng;Qi-Zhu Tang |
| 8 | CTRP3 attenuates cardiac dysfunction, inflammation, oxidative stress and cell death in diabetic cardiomyopathy in rats | 期刊论文 | Zhen-Guo Ma;Yu-Pei Yuan;Si-Chi Xu;Wen-Ying Wei;Chun-Ru Xu;Xin Zhang;Qing-Qing Wu;Hai-Han Liao;Jian Ni;Qi-Zhu Tang |
| 9 | C1q-tumour necrosis factor-related protein-3 exacerbates cardiac hypertrophy in mice | 期刊论文 | Zhen-Guo Ma;Yu-Pei Yuan;Xin Zhang;Si-Chi Xu;Chun-Yan Kong;Peng Song;Ning Li;Qi-Zhu Tang |
| 10 | STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3 | 期刊论文 | Ning Li;Heng Zhou;Hai-Ming Wu;Qing-Qing WuQ;Ming-Xia Duan;Wei Deng;Qi-Zhu Tang |
| 11 | Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway | 期刊论文 | Can Hu;Xin Zhang;Wen-Ying Wei;Ning Zhang;Hai-Ming Wu;Zhen-Guo Ma;Ling-Li Li;Wei Deng;Qi‐Zhu Tang |
| 12 | High-mobility group AT-hook 1 promotes cardiac dysfunction in diabetic cardiomyopathy via autophagy inhibition | 期刊论文 | Qing-Qing Wu;Chen Liu;Zhu-Lan Cai;Qing-Wen Xie;Tong-Tong Hu;Ming-Xia Duan;Hai-Ming Wu;Yuan Yuan;Qi‐Zhu Tang |
| 13 | Toll-like receptor 5 deficiency diminishes doxorubicin-induced acute cardiotoxicity in mice | 期刊论文 | Zhen-Guo Ma;Chun-Yan Kong;Hai-Ming Wu;Peng Song;Xin Zhang;Yu-Pei Yuan;Wei Deng;Qi-Zhu Tang |
| 14 | TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis | 期刊论文 | Fang-Yuan Liu;Di Fan;Zheng Yang;Nan Tang;Zhen Guo;Shu-Qing Ma;Zhen-Guo Ma;Hai-Ming Wu;Wei Deng;Qi-Zhu Tang |
| 15 | Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-gamma/AKT Pathways | 期刊论文 | Zhen-Guo Ma;Yu-Pei Yuan;Xin Zhang;Si-Chi Xu;Sha-Sha Wang;Qi-Zhu Tang |
| 16 | Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity | 期刊论文 | Can Hu;Xin Zhang;Ning Zhang;Wen-Ying Wei;Ling-Li Li;Zhen-Guo Ma;Qi-Zhu Tang |
| 17 | Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury | 期刊论文 | Ning Li;Wei Wang;Heng Zhou;Qing-Qing Wu;Ming-Xia Duan;Chen Liu;Hai-Ming Wu;Wei Deng;Di-Fei Shen;Qi‑Zhu Tang |
| 18 | Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway | 期刊论文 | Peng Song;Di-Fei Shen;Yan-Yan Meng;Chun-Yan Kong;Xin Zhang;Yu-Pei Yuan;Ling Yan;Qi-Zhu Tang;Zhen-Guo Ma |
| 19 | The protective effect of high mobility group protein HMGA2 in pressure overload-induced cardiac remodeling | 期刊论文 | Qing-Qing Wu;Yang Xiao;Chen Liu;Ming-Xia Duan;Zhu-Lan Cai;Sai-Yang Xie;Yuan Yuan;Hai-Ming Wu;Wei Deng;Qi‑Zhu Tang |
| 20 | Mnk1 (Mitogen-Activated Protein Kinase-Interacting Kinase 1) Deficiency Aggravates Cardiac Remodeling in Mice | 期刊论文 | Yuan Yuan;Ling Yan;Qing-Qing Wu;Heng Zhou;Ya-Ge Jin;Zhou-Yan Bian;Wei Deng;Zheng Yang;Di-Fei Shen;Xiao-Feng Zeng;Sha-Sha Wang;Hong-Liang Li;Qi-Zhu Tang |
| 21 | Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPK alpha/Smad3 signaling | 期刊论文 | Xin Zhang;Zhen-Guo Ma;Yu-Pei Yuan;Si-Chi Xu;Wen-Ying Wei;Peng Song;Chun-Yan Kong;Wei Deng;Qi-Zhu Tang |
| 22 | Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice | 期刊论文 | Xin Zhang;Can Hu;Ning Zhang;Wen-Ying Wei;Ling-Li Li;Hai-Ming Wu;Zhen-Guo Ma;Qi-Zhu Tang |
| 23 | Overexpression of CTRP3 protects against sepsis-induced myocardial dysfunction in mice | 期刊论文 | Wen-Ying Wei;Zhen-Guo Ma;Ning Zhang;Si-Chi Xu;Yu-Pei Yuan;Xiao-Feng Zeng;Qi-Zhu Tang |
| 24 | Aucubin protects against pressure overload-induced cardiac remodelling via the beta3 -adrenoceptor-neuronal NOS cascades. | 期刊论文 | Qing-Qing Wu;Yang Xiao;Ming-Xia Duan;Yuan Yuan;Xiao-Han Jiang;Zheng Yang;Hai-Han Liao;Wei Deng;Qi-Zhu Tang |
| 25 | Cardiac fibrosis: new insights into the pathogenesis | 期刊论文 | Zhen-Guo Ma;Yu-Pei Yuan;Hai-Ming Wu;Xin Zhang;Qi-Zhu Tang |
| 26 | CTRP3 protected against doxorubicin-induced cardiac dysfunction, inflammation and cell death via activation of Sirt1 | 期刊论文 | Yu-Pei Yuan;Zhen-Guo Ma;Xin Zhang;Si-Chi Xu;Xiao-Feng Zeng;Zheng Yang;Wei Deng;Qi-Zhu Tang |
| 27 | Leukocyte immunoglobulin-like receptor B4 protects against cardiac hypertrophy via SHP-2-dependent inhibition of the NF-κB pathway | 期刊论文 | Heng Zhou;Ning Li;Yuan Yuan;Ya-Ge Jin;Qing-Qing Wu;Ling Yan;Zhou-Yan Bian;Wei Deng;Di-Fei Shen;Hong-Liang Li;Qi-Zhu Tang |
| 28 | A77 1726 (leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice | 期刊论文 | Zhen-Guo Ma;Xin Zhang;Yu-Pei Yuan;Ya-Ge Jin;Ning Li;Chun-Yan Kong;Peng Song;Qi-Zhu Tang |
| 29 | T-bet deficiency attenuates cardiac remodelling in rats | 期刊论文 | Zhen-Guo Ma;Jia Dai;Yu-Pei Yuan;Zhou-Yan Bian;Si-Chi Xu;Ya-Ge Jin;Xin Zhang;Qi-Zhu Tang |
| 30 | Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway | 期刊论文 | Can Hu;Xin Zhang;Peng Song;Yu-Pei Yuan;Chun-Yan Kong;Hai-Ming Wu;Si-Chi Xu;Zhen-Guo Ma;Qi-Zhu Tang |
| 31 | Zingerone attenuates aortic banding-induced cardiac remodelling via activating the eNOS/Nrf2 pathway | 期刊论文 | Chen Liu;Qing-Qing Wu;Zhu-Lan Cai;Sai-Yang Xie;Ming-Xia Duan;Qing-Wen Xie;Yuan Yuan;Wei Deng;Qi-Zhu Tang |
| 32 | OX40 regulates pressure overload-induced cardiac hypertrophy and remodelling via CD4(+) T-cells | 期刊论文 | Qing-Qing Wu;Yuan Yuan;Xiao-Han Jiang;Yang Xiao;Zheng Yang;Zhen-Guo Ma;Hai-Han Liao;Yuan Liu;Wei Chang;Zhou-Yan Bian;Qi-ZhuTang |
| 33 | Autophagy is involved in the protective effect of p21 on LPS-induced cardiac dysfunction | 期刊论文 | Si‐Hui Huang;Man Xu;Li-Bo Liu;Jing-Jing Yang;Hui-Bo Wang;Chun-Xia Wan;Wei Deng;Qi-Zhu Tang |
| 34 | 心力衰竭的结构重构及其防治 | 奖励 | 唐其柱;沈涤非;邓伟;马振国;廖海含;吴青青;樊迪;徐蔓;周恒;严玲;孟妍妍;杨政;袁园;黄思慧;倪健 |
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