菱形蛋白酶iRhom2在抗DNA病毒天然免疫信号转导和炎症反应中的功能与机制研究
31671465
2016
C0702.细胞信号转导
李姝
面上项目
教授
武汉大学
60万元
炎症反应;MITA;NF-kB;TNFa/IL-1b;天然免疫
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | MARCH3 attenuates IL-1β-triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI. | 期刊论文 | Lin H;Gao D;Hu MM;Zhang M;Wu XX;Feng L;Xu WH;Yang Q;Zhong X;Wei J;Xu ZS;Zhang HX;Song ZM;Zhou Q;Ye W;Li S;Shu HB |
| 2 | ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response | 期刊论文 | Lian Huan;Wei Jin;Zang Ru;Ye Wen;Yang Qing;Zhang Xia Nan;Chen Yun Da;Fu Yu Zhi;Hu Ming Ming;Lei Cao Qi;Luo Wei Wei;Li Shu;Shu Hong Bing |
| 3 | SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA | 期刊论文 | Wei Guo;Jin Wei;Xuan Zhong;Ru Zang;Huan Lian;Ming-Ming Hu;Shu Li;Hong-Bing Shu;Qing Yang |
| 4 | SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA | 期刊论文 | Jin Wei;Huan Lian;Wei Guo;Yun Da Chen;Xia Nan Zhang;Ru Zang;Li Zhong;Qing Yang;Ming Ming Hu;Wei Wei Luo;Hong Bing Shu;Shu Li |
| 5 | The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation | 期刊论文 | Lin Heng;Li Shu;Shu Hong Bing |
| 6 | The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors | 期刊论文 | Huan Lian;Ru Zang;Jin Wei;Wen Ye;Ming Ming Hu;Yun Da Chen;Xia Nan Zhang;Yi Guo;Cao Qi Lei;Qing Yang;Wei Wei Luo;Shu Li;Hong Bing Shu |
| 7 | Virus-induced accumulation of intracellular bile acids activates the TGR5-beta-arrestin-SRC axis to enable innate antiviral immunity | 期刊论文 | Hu Ming Ming;He Wen Rui;Gao Peng;Yang Qing;He Ke;Cao Li Bo;Li Shu;Feng Yu Qi;Shu Hong Bing |
| 8 | iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA | 期刊论文 | Luo WW;Li S;Li C;Zheng ZQ;Cao P;Tong Z;Lian H;Wang SY;Shu HB;Wang YY |
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