USP18调控病毒感染诱导I型干扰素表达的机制研究

31671454
2016
C0702.细胞信号转导
钟波
面上项目
教授
武汉大学
62万元
接头蛋白;I型干扰素;去泛素化;信号转导;天然免疫
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 USP20 Promotes Cellular Antiviral Responses via Deconjugating K48-Linked Ubiquitination of MITA 期刊论文 Zhang Meng-Xin;Cai Zeng;Zhang Man;Wang Xiao-Meng;Wang Yaqin;Zhao Fei;Zhou Jing;Luo Min-Hua;Zhu Qiyun;Xu Zhigao;Zeng Wen-Bo;Zhong Bo;Lin Dandan
2 USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity 期刊论文 Zhang Q;Tang Z;An R;Ye L;Zhong B
3 Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS 期刊论文 Liuyu Tianzi;Yu Keying;Ye Liya;Zhang Zhidong;Zhang Man;Ren Yujie;Cai Zeng;Zhu Qiyun;Lin Dandan;Zhong Bo
4 USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA 期刊论文 Ye Liya;Zhang Qiang;Liuyu Tianzi;Xu Zhigao;Zhang Meng-Xin;Luo Min-Hua;Zeng Wen-Bo;Zhu Qiyun;Lin Dandan;Zhong Bo
5 USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2 期刊论文 Cai Z;Zhang MX;Tang Z;Zhang Q;Ye J;Xiong TC;Zhang ZD;Zhong B
6 Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3 期刊论文 Lu Bin;Ren Yujie;Sun Xueqin;Han Cuijuan;Wang Hongyan;Chen Yuxuan;Peng Qianqian;Cheng Yongbo;Cheng Xiaoliang;Zhu Qiyun;Li Wenxin;Li Hong-Liang;Du Hai-Ning;Zhong Bo;Huang Zan
7 CCL7 recruits cDC1 to promote antitumor immunity and facilitate checkpoint immunotherapy to non-small cell lung cancer 期刊论文 Zhang M;Yang W;Wang P;Deng Y;Dong TY;Liu FF;Huang R;Duan YQ;Liu XD;Lin D;Chu Q;Zhong B
8 The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer 期刊论文 Wang XM;Yang C;Zhao Y;Xu Z;Wang P;Yang W;Lin D;Xiong B;Fang J;Dong C;Zhong B
9 RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA 期刊论文 Zhang ZD;Xiong TC;Yao SQ;Wei MC;Zhang Q;Tang Z;Zhong B
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