基于GABA受体的家族性惊厥病发病机制研究
81901157
2019
H0901.神经系统发育与代谢异常
邹桂昌
青年科学基金项目
教授
中国科学技术大学
21万元
神经疾病;运动功能;发病机制;GABA受体;抗精神类药物
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Coordinated activity of a central pathway drives associative opioid analgesic tolerance | 期刊论文 | Yiwen Hou;Guichang Zou;Xianglian Wang;Hui Guo;Xiao Ma;Xingyu Cheng;Zhiyong Xie;Xin Zuo;Jing Xia;Huanhuan Mao;Man Yuan;Qi Chen;Peng Cao;Yupeng Yang;Li Zhang;Wei Xiong |
| 2 | Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction | 期刊论文 | Zou Guichang;Zuo Xin;Chen Kai;Ge Yushu;Wang Xiaoqun;Xu Guangwei;Wang Huan;Miao Chenjian;Xu Zhenyu;Tian Shuangshuang;Wang Zhen;Zhou Yifeng;Wei Wei;Huang Guangming;Liu Dan;Xiong Wei |
| 3 | Combined alcohol and cannabinoid exposure leads to synergistic toxicity by affecting cerebellar Purkinje cells | 期刊论文 | Guichang Zou;Jing Xia;Heyi Luo;Dan Xiao;Jin Jin;Chenjian Miao;Xin Zuo;Qianqian Gao;Zhi Zhang;Tian Xue;Yezi You;Ye Zhang;Li Zhang;Wei Xiong |
| 4 | Structural Basis of GABARAP-Mediated GABAA Receptor Trafficking and Functions on GABAergic Synaptic Transmission | 期刊论文 | Ye Jin;Zou Guichang;Zhu Ruichi;Kong Chao;Miao Chenjian;Zhang Mingjie;Li Jianchao;Xiong Wei;Wang Chao |
| 5 | Human Hyperekplexic Mutations in Glycine Receptors Disinhibit the Brainstem by Hijacking GABAA Receptors | 期刊论文 | Zou Guichang;Chen qi;Chen kai;Zuo xin;Ge yushu;Hou yiwen;Pan tao;Pan huilin;Liu dan;Zhang li;Xiong wei |
| 6 | The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABA(A) receptor isoform in a cell model of hyperekplexia | 期刊论文 | Zou Guichang;Xia Jing;Han Qianqian;Liu Dan;Xiong Wei |
| 7 | Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice | 期刊论文 | Yujun Guo;Guichang Zou;Keke Qi;Jin Jin;Lei Yao;Yang Pan;Wei Xiong |
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