ATP13A2通过调节锌离子稳态参与线粒体内Aβ产生和聚集的机制研究

81771174
2017
H0902.意识障碍与认知功能障碍
高慧玲
面上项目
副教授
东北大学
54万元
线粒体损伤;阿尔茨海默病;ATP13A2;β-淀粉样蛋白;锌离子稳态
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu2+-Mediated Aβ Aggregation 期刊论文 Xiaoyu Zhang;Xiancheng Zhang;Manli Zhong;Pu Zhao;Chuang Guo;You Li;He Xu;Tao Wang;Huiling Gao
2 Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons 期刊论文 Gao Huiling;Zheng Wei;Li Cheng;Xu He
3 一种作为影像学检查早期阿尔茨海默病示踪剂的短肽 专利 高慧玲;张宪成;张晓雨;王占友;钟曼丽
4 Nasal Delivery of D-Penicillamine Hydrogel Upregulates a Disintegrin and Metalloprotease 10 Expression via Melatonin Receptor 1 in Alzheimer’s Disease Models 期刊论文 Manli Zhong;Hejia Kou;Pu Zhao;Wei Zheng;He XU;Xiaoyu Zhang;Wang Lan;Chuang Guo;Tao Wang;Feng Guo;Zhanyou Wang;Huiling Gao
5 Screening a specific Zn(ii)-binding peptide for improving the cognitive decline of Alzheimer's disease in APP/PS1 transgenic mice by inhibiting Zn 2+-mediated amyloid protein aggregation and neurotoxicity 期刊论文 Xiaoyu Zhang;Manli Zhong;Pu Zhao;Xiancheng Zhang;You Li;Xuliang Wang;Jia Sun;Wang Lan;Hehong Sun;Zhanyou Wang;Huiling Gao
6 Selection of a d-Enantiomeric Peptide Specifically Binding to PHF6 for Inhibiting Tau Aggregation in Transgenic Mice 期刊论文 Xiancheng Zhang;Xiaoyu Zhang;Manli Zhong;Pu Zhao;Chuang Guo;You Li;Tao Wang;Huiling Gao
7 Brain Targeting and Aβ Binding Bifunctional Nanoparticles Inhibit Amyloid Protein Aggregation in APP/PS1 Transgenic Mice. 期刊论文 Xiancheng Zhang;Xiaoyu Zhang;You Li;Manli Zhong;Pu Zhao;Chuang Guo;He Xu;Tao Wang;Huiling Gao
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享