基于维药阿里红的急性髓系白血病靶向精准治疗药物发现
U1803122
2018
B0607.环境毒理与健康
李华
联合基金项目
教授
华中科技大学
56万元
急性髓系白血病;异柠檬酸脱氢酶;阿里红;基于结构药物发现;靶向治疗
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Withanolides isolated from Tubocapsicum anomalum and their antiproliferative activity. | 期刊论文 | Xiang Ke;Li Chen;Li Ming-Xue;Song Zhuo-Rui;Ma Xiao-Xin;Sun De-Juan;Li Hua;Chen Li-Xia |
| 2 | 3-Phosphoglycerate dehydrogenase: a potential target for cancer treatment. | 期刊论文 | Li Mingxue;Wu Canrong;Yang Yueying;Zheng Mengzhu;Yu Silin;Wang Jinhui;Chen Lixia;Li Hua |
| 3 | Withanolides from dietary tomatillo suppress HT1080 cancer cell growth by targeting mutant IDH1. | 期刊论文 | Yang Yueying;Xiang Ke;Sun Dejuan;Zheng Mengzhu;Song Zhuorui;Li Mingxue;Wang Xuanbin;Li Hua;Chen Lixia |
| 4 | Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction. | 期刊论文 | Zhou Xuechen;Zheng Mengzhu;Zhao Na;Hu Yixin;Yang Kaiyin;Huo Junfeng;Liu Guangyuan;Huang Jiangeng;Chen Lixia;Zhou Yirong;Li Hua |
| 5 | Chemical Components of the Fruits of Morus nigra Linn.: Methyl Caffeate as a Potential Anticancer Agent by Targeting 3-Phosphoglycerate Dehydrogenase. | 期刊论文 | Wang Yali;Zheng Mengzhu;Jiang Qinghua;Xu Yang;Zhou Xuechen;Zhang Na;Sun Dejuan;Li Hua;Chen Lixia |
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