基于“基因-脑-行为”框架探讨nNOS/NO通路关键基因NOS1在ADHD发病机制中的作用

81873802
2018
H1008.儿童和青少年精神行为障碍
刘璐
面上项目
副研究员
北京大学
56万元
行为;脑影像;多模态融合;注意缺陷多动障碍;神经元型一氧化氮合酶基因
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Shared and distinct resting functional connectivity in children and adults with attention-deficit/hyperactivity disorder 期刊论文 Guo XJ;Yao DR;Cao QJ;Liu L;Zhao QH;Li H;Huang F;Wang YF;Qian QJ;Wang YF;Calhoun VD;Johnstone SJ;Sui J;Sun L
2 儿童共病不同类型破坏性行为障碍的神经机制:基于执行功能和近红外脑成像技术的研究 奖励 Liu NN;Jia GD;Qiu SW;Li HM;Liu YF;Wang YF;Niu HJ;Liu L;Qian QJ
3 Cortical Morphometric Abnormality and Its Association with Working Memory in Children with Attention-Deficit/Hyperactivity Disorder 期刊论文 Si FF;Liu L;Li HM;Sun L;Cao QJ;Lu HN;Wang YF;Qian QJ
4 A potential association of RNF219-AS1 with ADHD: Evidence from categorical analysis of clinical phenotypes and from quantitative exploration of executive function and white matter microstructure endophenotypes 期刊论文 Fu GH;Chen W;Li HM;Wang YF;Liu L;Qian QJ
5 Affective-cognitive-behavioral heterogeneity of Attention-Deficit/Hyperactivity Disorder (ADHD): Emotional dysregulation as a sentinel symptom differentiating “ADHD-simplex” and “ADHD-complex” syndromes? 期刊论文 Yue XX;Liu L;Chen W;Preece DA;Liu QR;Li HM;Wang YF;Qian QJ
6 Disrupted signal variability of spontaneous neural activity in children with attention-deficit/hyperactivity disorder 期刊论文 Hu ZY;Liu L;Wang MJ;Jia GD;Li HM;Si FF;Dong M;Qian QJ;Niu HJ
7 The potential shared brain functional alterations between adults with ADHD and children with ADHD co-occurred with disruptive behaviors 期刊论文 Liu NN;Jia GD;Li HM;Zhang SY;Wang YF;Niu HJ;Liu L;Qian QJ
8 Genetic alteration of CADM1 is associated with ADHD during early life: An exploratory study with genetic, neuroimaging and animal model methods 奖励 Jin JL;Liu L;Gao Q;Li HM;Wang YF;Qian QJ
9 Unraveling the Optimum Latent Structure of Attention-Deficit/Hyperactivity Disorder: Evidence Supporting ICD and HiTOP Frameworks 期刊论文 Gomez R;Liu L;Krueger R;Stavropoulos V;Downs J;Preece D;Houghton S;Chen W
10 注意缺陷多动障碍共患阅读障碍:认知-脑-基因的多维度研究进展 期刊论文 王久菊;孙黎;舒华;刘璐;王玉凤
11 Emotion dysregulation in adults with ADHD: The role of cognitive reappraisal and expressive suppression 期刊论文 Liu QR;Chen W;Preece DA;Xu DF;Li HM;Liu NN;Fu GH;Wang YF;Qian QJ;Gross JJ;Liu L
12 Relationships between sensory integration and the core symptoms of attention-deficit/hyperactivity disorder: the mediating effect of executive function 期刊论文 Li J;Wang WC;Cheng J;Li HM;Feng L;Ren YC;Liu L;Qian QJ;Wang YF
13 The potential involvement of Long noncoding RNA in the pathogenesis of ADHD: candidate gene and whole transcriptome analyses in Chinese Han subjects 奖励 付广慧;刘倩溶;黄兴;李海梅;刘宁宁;周怡;王文辰;王玉凤;刘璐;钱秋谨
14 成人ADHD患者抑制功能缺陷相关多模态影像学特征及其潜在的“基因-脑-认知功能”通路 奖励 郭晓杰;刘璐;李甜甜;赵琦华;李卉;黄芳;王延菲;钱秋谨;王玉凤;隋婧;孙黎
15 Monoaminergic Genetic Variants, Prefrontal Cortex–Amygdala Circuit, and Emotional Symptoms in Children With ADHD: Exploration Based on the Gene–Brain–Behavior Relationship 期刊论文 Liu L;Zhao QH;Yu XY;Xu DF;Li HM;Ji N;Wu ZM;Cheng J;Su Y;Cao QJ;Sun L;Qian QJ;Wang YF
16 Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5 期刊论文 Liu L;Feng XK;Li HM;Li SC;Qian QJ;Wang YF
17 Network analysis of 18 attention-deficit/hyperactivity disorder symptoms suggests the importance of " Distracted" and " Fidget" as central symptoms: Invariance across age, gender, and subtype presentations 期刊论文 Liu L;Wang Y;Chen W;Gao Y;Li HM;Wang YF;Chan RCK;Qian QJ
18 Interference of default mode on attention in adults with attention-deficit/hyperactivity disorder and its association with genetic variants and treatment ourcomes 奖励 Liu L;Chen D;Huang F;Jia TY;Cheng W;Pan MR;Zhao MJ;Bu X;Liao XH;Wang YF;Cao M;Qian QJ;Feng JF
19 Alterations of cerebral perfusion and functional brain connectivity in medication-naïve male adults with attention-deficit/hyperactivity disorder 期刊论文 Tan YW;Liu L;Wang YF;Li HM;Pan MR;Zhao MJ;Huang F;Wang YF;He Y;Liao XH;Qian QJ
20 Different functional alteration in attention-deficit/hyperactivity disorder across developmental age groups: a meta-analysis and an independent validation of resting-state functional connectivity studies 期刊论文 Liu NN;Liu QR;Yang ZQ;Xu J;Fu GH;Zhou Y;Li HM;Wang YF;Liu L;Qian QJ
21 Inhibition-directed multimodal imaging fusion patterns in adults with ADHD and its potential underlying "gene-brain-cognition" relationship 期刊论文 Guo XJ;Liu L;Li TT;Zhao QH;Li H;Huang F;Wang YF;Qian QJ;Cao QJ;Wang YF;Calhoun VD;Sui J;Sun L
22 The neural correlations of spatial attention and working memory deficits in adults with ADHD 期刊论文 Luo XS;Guo JL;Liu L;Zhao XX;Li DW;Li H;Zhao QH;Wang YF;Qian QJ;Wang YF;Song Y;Sun L
23 Disrupted functional brain connectivity networks in children with attention-deficit/hyperactivity disorder: Evidence from resting-state functional near-infrared spectroscopy 期刊论文 Wang M.;Hu Z.;Liu L.;Li H.;Qian Q.;Niu H.
24 The potential influence of comorbid with oppositional defiant disorder and conduct disorder on the executive function impairments in medication-naive children with attention-deficit/hyperactivity disorder 期刊论文 Liu NN;Jia GD;Qiu SW;Li HM;Liu YF;Wang YF;Niu HJ;Liu L;Qian QJ
25 Atypical developmental trajectories of early perception among school-age children with attention deficit hyperactivity disorder during a visual search task 期刊论文 Luo XS;Guo JL;Li DW;Liu L;Chen YB;Zhu Y;Johnstone SJ;Wang YF;Song Y;Sun L
26 The implicated roles of cell adhesion molecule 1 (CADM1) gene and altered prefrontal neuronal activity in attention-deficit/ hyperactivity disorder: A “gene– brain–behavior relationship”? 期刊论文 Jin JL;Liu L;Chen W;Gao Q;Li HM;Wang YF;Qian QJ
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