Trio基因缺失或突变导致孤独症样行为的脑区结构基础和分子机制

81871077
2018
H1008.儿童和青少年精神行为障碍
李俊
面上项目
副研究员
北京大学
56万元
孤独症;异常行为;分子机制;Trio基因;神经发育
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling 期刊论文 Zhang Zhengrong;Ye Maoqing;Li Qiongwei;You Yang;Yu Hao;Ma Yuanlin;Mei Liwei;Sun Xiaqin;Wang Lifang;Yue Weihua;Li Rena;Li Jun;Zhang Dai
2 Family-based association study identifies SNAP25 as a susceptibility gene for autism in the Han Chinese population 期刊论文 Wang Ziqi;Li Jun;Zhang Tian;Lu Tianlan;Wang Han;Jia Meixiang;Liu Jing;Xiong Jun;Zhang Dai;Wang Lifang
3 Association between CNTNAP2 polymorphisms and autism: A family-based study in the chinese han population and a meta-analysis combined with GWAS data of psychiatric genomics consortium 期刊论文 Zhang Tian;Zhang Jishui;Wang Ziqi;Jia Meixiang;Lu Tianlan;Wang Han;Yue Weihua;Zhang Dai;Li Jun;Wang Lifang
4 Dysfunction of Trio GEF1 involves in excitatory/inhibitory imbalance and autism-like behaviors through regulation of interneuron migration. 期刊论文 Sun Xiaoxuan;Wang Lifang;Wei Chengwen;Sun Mengwen;Li Qiongwei;Meng Hu;Yue Weihua;Zhang Dai;Li Jun
5 RhoGEF Trio Regulates Radial Migration of Projection Neurons via Its Distinct Domains 期刊论文 Wei Chengwen;Sun Mengwen;Sun Xiaoxuan;Meng Hu;Li Qiongwei;Gao Kai;Yue Weihua;Wang Lifang;Zhang Dai;Li Jun
6 Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms. 期刊论文 Li Jun;Sun Xiaoxuan;You Yang;Li Qiongwei;Wei Chengwen;Zhao Linnan;Sun Mengwen;Meng Hu;Zhang Tian;Yue Weihua;Wang Lifang;Zhang Dai
7 Family-based association study of ZNF804A polymorphisms and autism in a Han Chinese population 期刊论文 Wang Ziqi;Zhang Tian;Liu Jing;Wang Han;Lu Tianlan;Jia Meixiang;Zhang Dai;Wang Lifang;Li Jun
8 P-Rex1 Overexpression Results in Aberrant Neuronal Polarity and Psychosis-Related Behaviors. 期刊论文 Li Qiongwei;Wang Lifang;Ma Yuanlin;Yue Weihua;Zhang Dai;Li Jun
9 Replication of previous GWAS hits suggests the association between rs4307059 near MSNP1AS and autism in a Chinese Han population 期刊论文 Wang Ziqi;Zhang Jishui;Lu Tianlan;Zhang Tian;Jia Meixiang;Ruan Yanyan;Zhang Dai;Li Jun;Wang Lifang
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