嗜麦芽寡养单胞菌多肽修饰酶催化机理研究与应用
31870055
2018
C0102.微生物生理与生化
吴边
面上项目
研究员
中国科学院微生物研究所
61万元
蛋白质工程;多肽修饰;底物识别;微生物酶催化;化学生物学
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Traceless enzymatic protein synthesis without ligation sites constraint | 期刊论文 | Li Ruifeng;Schmidt Marcel;Zhu Tong;Yang Xinya;Feng Jing;Tian Yu'e;Cui Yinglu;Nuijens Timo;Wu Bian |
| 2 | Recent advances in biocatalysis of nitrogen-containing heterocycles | 期刊论文 | Jing Feng;Wen-Chao Geng;Huifeng Jiang;Bian Wu |
| 3 | Development of a versatile and efficient C-N lyase platform for asymmetric hydroamination via computational enzyme redesign | 期刊论文 | Cui Yinglu;Wang Yinghui;Tian Wenya;Bu Yifan;Li Tao;Cui Xuexian;Zhu Tong;Li Ruifeng;Wu Bian |
| 4 | Creating an unusual glycine-rich motif in a peptide amidase leads to versatile protein C-terminal traceless functionalization | 期刊论文 | Tong Zhu;Yinglu Cui;Wenchao Geng;Guoxia Liu;Huifeng Jiang;Ruifeng Li;Bian Wu |
| 5 | Computational enzyme redesign: large jumps in function | 期刊论文 | Yinglu Cui;Jinyuan Sun;Bian Wu |
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