揭示乙型肝炎表面抗原新突变对病毒复制的影响及突变株传播的新途径
81772174
2017
H2103.肝炎病毒与感染
李彤
面上项目
副教授
北京大学
56万元
乙型肝炎病毒;突变;细胞间直接传播;复制和分泌;乙型肝炎表面抗原
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The enhancement role of Matrigel on HBV infection in HepG2-NTCP cells | 期刊论文 | Ji Song;Guomin Ou;Xinyuan Lai;Xing Tian;Luwei Wang;Kai Zhang;Lei Wang;Xuechao Zhang;Chengyu Zhao;Hui Zhuang;Kuanhui Xiang;Tong Li |
| 2 | Characteristics of HBV infection in 705 HIV-infected patients under lamivudine-based antiretroviral treatment from three regions in China | 期刊论文 | Mingze Su;Lingjie Liao;Hui Xing;Shuai Wang;Yutang Li;Wei Lu;Lingyuan He;Juan Deng;Yiming Shao;Tong Li;Hui Zhuang |
| 3 | Naturally occurring mutations within HBV surface promoter II sequences affect transcription activity, HBsAg and HBV DNA levels in HBeAg-positive chronic hepatitis B patients | 期刊论文 | Ran Hao;Kuanhui Xiang;Yan Shi;Dong Zhao;Huifang Tian;Baohong Xu;Yufang Zhu;Huan Dong;Hai Ding;Hui Zhuang;Jie Hu;Tong Li |
| 4 | The modulation of HBsAg level by sI126T is affected by additional amino acid substitutions in the S region of HBV | 期刊论文 | Lingyuan He;Mingze Su;Guomin Ou;Luwei Wang;Juan Deng;Hui Zhuang;Kuanhui Xiang;Tong Li |
| 5 | 乙型肝炎小表面蛋白sC76Y和sI218L新突变的发现及体外研究 | 期刊论文 | 王璐薇;苏明泽;欧国敏;和凌媛;李垚;庄辉;向宽辉;李彤 |
| 6 | The genotype (A to H) dependent N-terminal sequence of HBV large surface protein affects viral replication, secretion and infectivity | 期刊论文 | Gumin Ou;Lingyuan He;Luwei Wang;Ji Song;Xinyuan Lai;Xing Tian;Lei Wang;Kai Zhang;Xuechao Zhang;Juan Deng;Hui Zhuang;Kuanhui Xiang;Tong Li |
| 7 | The effect of the hepatitis B virus surface protein truncated sC69 mutation on viral infectivity and the host innate immune response | 期刊论文 | Kuanhui Xiang;Yiwei Xiao;Yao Li;Lingyuan He;Luwei Wang;Hui Zhuang;Tong Li |
| 8 | A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection | 期刊论文 | Kai Zhang;Xinyuan Lai;Ji Song;Lingyuan He;Luwei Wang;Guomin Ou;Xing Tian;Lei Wang;Juan Deng;Jiajia Zhang;Chuanyun Li;Hui Zhuang;Tong Li;Kuanhui Xiang |
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