基于肿瘤微环境修复和治疗的纳米递药系统与肿瘤微环境修复机制研究

81673365
2016
H3408.药剂学
齐宪荣
面上项目
教授
北京大学
60万元
多模态肿瘤治疗;修复机理;肿瘤微环境修复;纳米递药系统;靶向递送
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Construction of Hyaluronic Tetrasaccharide Clusters Modified Polyamidoamine siRNA Delivery System 期刊论文 Yingcong Ma;Meng Sha;Shixuan Cheng;Wang Yao;Zhongjun Li;Xian-Rong Qi
2 Amphiphilic dendrimer engineered nanocarrier systems for co-delivery of siRNA and paclitaxel to matrix metalloproteinase-rich tumors for synergistic therapy 期刊论文 Xin Li;A-ning Sun;Yu-jie Liu;Wen-jie Zhang;Ning Pang;Shi-xuan Cheng;Xian-rong Qi
3 Taming the Wildness of "Trojan-Horse" Peptides by Charge-Guided Masking and Protease-Triggered Demasking for the Controlled Delivery of Antitumor Agents 期刊论文 Shi Nian-Qiu;Qi Xian-Rong
4 Interfacial properties and micellization of triblock poly(ethylene glycol)-poly(ε- caprolactone)-polyethyleneimine copolymers 期刊论文 Ji Li;Yitian Du;Haitao Su;Shixuan Cheng;Yanxia Zhou;Yiguang Jin;Xian-Rong Qi
5 Enhancing solid tumor therapy with sequential delivery of dexamethasone and docetaxel engineered in a single carrier to overcome stromal resistance to drug delivery 期刊论文 Lu Zhang;Haitao Su;Yujie Liu;Ning Pang;Ji Li;Xian-Rong Qi
6 亚麻酸与抗癌药物前药及该前药的低密度脂蛋白组合物 专利 齐宪荣;苏海滩
7 Characterization of amphiphilic dendrimer modified PEG-PLA nanoparticles prepared by a double emulsion-solvent evaporation method 期刊论文 Xin Li;Ning Pang;Ji Li;Xianrong Qi
8 Tunable gold nanostar synthesis with surfactant-free system 期刊论文 Xupeng Yang;Zhenzhen Yang;Lu Zhang;Qi Sun;Xianrong Qi
9 Prior anti-CACAFs break down the CACAFs barrier and improve accumulation of docetaxel micelles in tumor 期刊论文 Ning Pang;Ji Li;A ning Sun;Zhenzhen Yang;Shixuan Cheng;Xian-Rong Qi
10 Preparation, characterization and pharmacokinetics of 10-hydroxycamptothecin nanosuspension 期刊论文 张毅;詹颖;庞宁;刘瑜洁;程士轩;李骥;杜祎甜;齐宪荣
11 Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation 期刊论文 Liu Yu-Jie;Ma Ying-Cong;Zhang Wen-Jie;Yang Zhen-Zhen;Liang De-Sheng;Wu Zhi-Fu;Qi Xian-Rong
12 Albumin-Based Nanotheranostic Probe with Hypoxia Alleviating Potentiates Synchronous Multimodal Imaging and Phototherapy for Glioma 期刊论文 Zhenzhen Yang;Yitian Du;Qi Sun;Yiwei Peng;Rudong Wang;Yu Zhou;Yuqi Wang;Chunli Zhang;Xianrong Qi
13 Treating metastatic triple negative breast cancer with CD44/neuropilin dual molecular targets of multifunctional nanoparticles 期刊论文 Liang De-Sheng;Zhang Wen-Jie;Wang Ai-Ting;Su Hai-Tao;Zhong Hai-Jun;Qi Xian-Rong
14 Delivering siRNA and Chemotherapeutic Molecules Across BBB and BTB for Intracranial Glioblastoma Therapy 期刊论文 Yang Zhen-zhen;Gao Wei;Liu Yu-jie;Pang Ning;Qi Xian-rong
15 紫杉醇微球-原位凝胶的制备及其局部注射的抗肿瘤药效 期刊论文 詹颖;杜祎甜;仰浈臻;张春丽;齐宪荣
16 中华人民共和国教育部高等学校科学研究优秀成果奖(科学技术)肿瘤线粒体和耐药屏障与拟态血管靶向性给药系统的研究 奖励 吕万良;张强;齐宪荣;王学清;据瑞军;姚红娟;仰浈臻;李秀英;张扬
17 Phototherapy and anti-GITR antibody-based therapy synergistically reinvigorate immunogenic cell death and reject established cancers 期刊论文 Qi Sun;Zhenzhen Yang;Meng Lin;Yiwei Peng;Rudong Wang;Yitian Du;Yu Zhou;Jiajia Li;Xianrong Qi
18 Interferon-liposomes prepared to make macroglia maintain M1 phenotype 期刊论文 杜祎甜;张泸;詹颖;柴新宇;李锴森;齐宪荣
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