5-HT2B受体促动脉粥样硬化作用及其机制研究
81670408
2016
H0214.动脉粥样硬化与动脉硬化
刘雅涵
面上项目
助理研究员
北京大学
52万元
平滑肌细胞;五羟色胺;动脉粥样硬化;信号转导;受体
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 降低5-HT2BR含量和抑制其活性的物质在制备治疗和预防动脉粥样硬化产品中的应用 | 专利 | 汪南平;刘雅涵;王志鹏 |
| 2 | Inhibition of 5-HT2BR Reduced Vascular Restenosis and Mitigated β-arrestin2-mTOR/p70S6K Pathway | 会议论文 | Yahan Liu;Zhipeng Wang;Jing Li;Yiqian Ban;Guangmei Mao;Man Zhang;Mo Wang;Yingjia Li;Yaohua Xu;Hao Ming;Yan Liu;Beilei Zhao;Qiang Shen;Qingbo Xu;Nanping Wang |
| 3 | 5-HT2BR Promoted Vascular Restenosis via β-arrestin2-mTOR/p70S6K Pathway | 会议论文 | Yahan Liu;Zhipeng Wang;Jing Li;Yiqian Ban;Guangmei Mao;Man Zhang;Mo Wang;Yingjia Li;Yaohua Xu;Hao Ming;Yan Liu;Beilei Zhao;Qiang Shen;Qingbo Xu;Nanping Wang |
| 4 | Inhibition of 5-Hydroxytryptamine Receptor 2B Reduced Vascular Restenosis and Mitigated the-Arrestin2-Mammalian Target of Rapamycin/p70S6K Pathway | 期刊论文 | Liu Yahan;Wang Zhipeng;Li Jing;Ban Yiqian;Mao Guangmei;Zhang Man;Wang Mo;Liu Yan;Zhao Beilei;Shen Qiang;Xu Qingbo;Wang Nanping |
| 5 | S-nitrosation impairs KLF4 activity and instigates endothelial dysfunction in pulmonary arterial hypertension | 期刊论文 | Ban Yiqian;Liu Yahan;Li Yazi;Zhang Yuying;Xiao Lei;Gu Yue;Cheng Shaoliang;Zhao Beilei;Chen Chang;Wang Nanping |
| 6 | GHSR mediates myofibroblast differentiation and macrophage inflammatory response in cardiac remodeling | 会议论文 | Mo Wang;Yahan Liu;Jing Li;Yingjia Li;Hao Ming;Man Zhang;Li Fang;Zhipeng Wang;Yaohua Xu;Yiqian Ban;Nanping Wang |
| 7 | GHSR deficiency exacerbates cardiac fibrosis: role in macrophage inflammasome activation and myofibroblast differentiation | 期刊论文 | Mo Wang;Lei Qian;Jing Li;Hao Ming;Li Fang;Yingjia Li;Man Zhang;Yaohua Xu;Yiqian Ban;Weizhen Zhang;Youyi Zhang;Yahan Liu;Nanping Wang |
| 8 | Inhibition of 5-HT2BR Reduced Vascular Restenosis and Mitigated β-arrestin2-mTOR/p70S6K Pathway | 会议论文 | Yahan Liu;Zhipeng Wang;Jing Li;Yiqian Ban;Guangmei Mao;Man Zhang;Mo Wang;Yingjia Li;Yaohua Xu;Hao Ming;Yan Liu;Beilei Zhao;Qiang Shen;Qingbo Xu;Nanping Wang |
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