结核菌酪氨酸磷酸酶（PtpA）小分子抑制剂的筛选及其对潜伏期分子机制研究
30973665
2009
H3404.生物技术药物
张立新
面上项目
教授
中国科学院微生物研究所
34万元
巨噬细胞;耐药结核;PtpA;天然产物库;潜伏结核
2010-01-01到2012-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Systematics-guided bioprospecting for bioactive microbial natural products | 期刊论文 | Liu, Xueting|Bolla, Krishna|Ashforth, Elizabeth Jane|Zhuo, Ying|Gao, Hong|Huang, Pei|Stanley, Sarah A.|Hung, Deborah T.|Zhang, Lixin| |
| 2 | Brevianamides with Antitubercular Potential from a Marine-Derived Isolate of Aspergillus versicolor | 期刊论文 | Song Fuhang|Song Fuhang|Liu Mei|Liu Mei|Liu Xueting|Liu Xueting|Dai Huanqin|Dai Huanqin|Zhang Lixin|Zhang Lixin|Capon Robert J.|Capon Robert J.|Liu Xinru|Liu Xinru|Guo Hui|Guo Hui|Ren Biao|Ren Biao|Chen Caixia|Chen Caixia|Piggott Andrew M.|Piggott Andrew |
| 3 | A marine-derived Streptomyces sp. MS449 produces high yield of actinomycin X(2) and actinomycin D with potent anti-tuberculosis activity | 期刊论文 | Chen Caixia|Chen Caixia|Yang Na|Yang Na|Xie Feng|Xie Feng|Yu Ke|Yu Ke|Chen Ruxian|Chen Ruxian|Zhang Lixin|Zhang Lixin|Song Fuhang|Song Fuhang|Wang Qian|Wang Qian|Abdel-Mageed WM|Abdel-Mageed WM|Guo Hui|Guo Hui|Fu Chengzhang|Fu Chengzhang|Hou Weiyuan|Hou W |
| 4 | Quinazolin-4-one Coupled with Pyrrolidin-2-iminium Alkaloids from Marine-Derived Fungus Penicillium aurantiogriseum | 期刊论文 | Song, Fuhang|Song, Fuhang|Tong, Yaojun|Tong, Yaojun|Dai, Huanqin|Dai, Huanqin|Bai, Hua|Bai, Hua|Wang, Jidong|Wang, Jidong|Zhang, Lixin|Zhang, Lixin|Ren, Biao|Ren, Biao|Yu, Ke|Yu, Ke|Chen, Caixia|Chen, Caixia|Guo, Hui|Guo, Hui|Yang, Na|Yang, Na|Gao, Hong|G |
| 5 | Abyssomicins from a South China Sea deep-sea sediment Verrucosispora sp.: Natural thioether Michael addition adducts as potential antitubercular prodrugs | 期刊论文 | Wang Qian|Wang Qian|He Wenni|He Wenni|Xie Feng|Xie Feng|Dai Huanqin|Dai Huanqin|Liu Miaomiao|Liu Miaomiao|Chen Caixia|Chen Caixia|Xu Hao|Xu Hao|Liu Mei|Liu Mei| PiggottAndrew M.| PiggottAndrew M.|Liu Xueting|Liu Xueting|Robert J. Capon|Robert J. Capon|Son |
| 6 | Isolation and characterization of LS1924A, a new analog of emycins | 期刊论文 | Chen, Caixia|Chen, Caixia|Song, Fuhang|Song, Fuhang|Guo, Hui|Guo, Hui|Abdel-Mageed, Wael M.|Abdel-Mageed, Wael M.|Bai, Hua|Bai, Hua|Dai, Huanqin|Dai, Huanqin|Liu, Xueting|Liu, Xueting|Wang, Jidong|Wang, Jidong|Zhang, Lixin|Zhang, Lixin| |
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