RDGN网络调控前列腺癌发生发展的分子机制及潜在临床应用

81172422
2011
H1825.肿瘤学研究临床转化
吴孔明
面上项目
教授
华中科技大学
58万元
肿瘤转移;AR;DACH1;前列腺癌;抑癌基因
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Double homozygous missense mutations in DACH1 and BMP4 in a patient with bilateral cystic renal dysplasia 期刊论文 Pestell RG|Muller-Wiefel DE|Schaefer F|Weber S|
2 The inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism. 期刊论文 Wu K|Yu Z|Wang C|Chen K|
3 Silencing DACH1 Promotes Esophageal Cancer Growth by Inhibiting TGF-beta Signaling 期刊论文 Liang H|Zhan Q|Li W|Guo M|
4 DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells. 期刊论文 Chen Y,|Guo M|Yu S|Wu K|
5 Epigenetic silencing of DACH1 induces loss of transforming growth factor-β1 antiproliferative response in human hepatocellular carcinoma. 期刊论文 Li Y|Jing K|Yang Y|Guo M|
6 The DACH/EYA/SIX gene network and its role in tumor initiation and progression. 期刊论文 Xu H|Zhang C|Yin T|Wu K|
7 DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling 期刊论文 Yu S|Zhang C|Yin T|Wu K.|
8 The endogenous Cell-Fate Factor Dachshund restrains prostate epithelial cellmigration via repression of cytokine secretion via a CXCL Signaling Module. 期刊论文 Wang C|Davis RJ|Mardon G|Pestell RG|
9 DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells 期刊论文 Chen Y|Guo M|Yu S|Wu K|
10 Cell Fate Factor DACH1 Represses YB-1-mediated Oncogenic Transcription and Translation 期刊论文 Lisanti MP|Quong A|Ertel A|Pestell RP|
11 Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application. 期刊论文 Chu Q|Yu S|Chen Y|Wu K|
12 Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-β signalling. 期刊论文 Lu Y|Zhang Z|Yang Y|Guo M|
13 DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling 期刊论文 Guo M|Yu S|Chen Y|Wu K|
14 Cell Fate Factor DACH1 Represses YB-1-mediated Oncogenic Transcription and Translation 期刊论文 Lisanti MP|Quong A|Ertel A|Pestell RP|
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