TET1/BER通路在环境化学物致肺癌过程中介导表观遗传调控的作用机制研究
81573114
2015
H3001.环境卫生
刘文斌
面上项目
教授
中国人民解放军第三军医大学
50万元
DNA羟甲基化;碱基切除修复;化学致癌;TET1;DNA甲基化
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | aFARP-ChIP-seq, a convenient and reliable method for genome profiling in as few as 100 cells with a capability for multiplexing ChIP-seq | 期刊论文 | Liu Wenbin;Yue Sibiao;Zheng Xiaobin;Hu Minjie;Cao Jia;Zheng Yixian |
| 2 | Diagnostic and prognostic value of the BEX family in lung adenocarcinoma. | 期刊论文 | Zhang Zhong Hao;Luan Zhi Yu;Han Fei;Chen Hong Qiang;Liu Wen Bin;Liu Jin Yi;Cao Jia |
| 3 | Copy number variations and expression of MPDZ are prognostic biomarkers for clear cell renal cell carcinoma. | 期刊论文 | Huang Yong-Sheng;Liu Wen-Bin;Han Fei;Yang Jun-Tang;Hao Xiang-Lin;Chen Hong-Qiang;Jiang Xiao;Yin Li;Ao Lin;Cui Zhi-Hong;Cao Jia;Liu Jin-Yi |
| 4 | TMEM196 hypermethylation as a novel diagnostic and prognostic biomarker for lung cancer | 期刊论文 | Liu Wen Bin;Han Fei;Huang Yong Sheng;Chen Hong Qiang;Chen Jian Ping;Wang Dan Dan;Jiang Xiao;Yin Li;Cao Jia;Liu Jin Yi |
| 5 | Epigenetic inactivation of LHX6 mediated microcystin-LR induced hepatocarcinogenesis via the Wnt/beta-catenin and P53 signaling pathways. | 期刊论文 | Chen Hong Qiang;Zhao Ji;Li Yan;Huang Yu Jing;Chen Dong Jiao;He Li Xiong;Wang Ling Qiao;Zheng Chuan Fen;Wang Jia;Cao Jia;Shu Wei Qun;Liu Jin Yi;Liu Wen Bin |
| 6 | Epigenetic silencing of ALX4 regulates microcystin-LR induced hepatocellular carcinoma through the P53 pathway. | 期刊论文 | Zhao Ji;Chen Hong Qiang;Yang Hui Fang;Li Yan;Chen Dong Jiao;Huang Yu Jing;He Li Xiong;Zheng Chuan Fen;Wang Ling Qiao;Wang Jia;Zhang Na;Cao Jia;Liu Jin Yi;Shu Wei Qun;Liu Wen Bin |
| 7 | Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells | 期刊论文 | Chen Hong Qiang;Zhao Ji;Li Yan;He Li Xiong;Huang Yu Jing;Shu Wei Qun;Cao Jia;Liu Wen Bin;Liu Jin Yi |
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