Rictor调控actin细胞骨架聚合在雌激素改善学习记忆中的作用与机制研究

81571059
2015
H0902.意识障碍与认知功能障碍
张吉强
面上项目
教授
中国人民解放军第三军医大学
57万元
阿尔茨海默病;突触可塑性;雌激素;Rictor;学习记忆障碍
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice 期刊论文 Zhao Yangang;He Li;Zhang Yuanyuan;Zhao Jikai;Liu Zhi;Xing Fangzhou;Liu Mengying;Feng Ziqi;Li Wei;Zhang Jiqiang
2 Orchiectomy and letrozole differentially regulate synaptic plasticity and spatial memory in a manner that is mediated by SRC-1 in the hippocampus of male mice 期刊论文 Zhao Jikai;Bian Chen;Liu Mengying;Zhao Yangang;Sun Tao;Xing Fangzhou;Zhang Jiqiang
3 Nuclear and membrane estrogen receptor antagonists induce similar mTORC2 activation-reversible changes in synaptic protein expression and actin polymerization in the mouse hippocampus 期刊论文 Xing Fang Zhou;Zhao Yan Gang;Zhang Yuan Yuan;He Li;Zhao Ji Kai;Liu Meng Ying;Liu Yan;Zhang Ji Qiang
4 Letrozole regulates actin cytoskeleton polymerization dynamics in a SRC-1 dependent manner in the hippocampus of mice. 期刊论文 Zhao Yangang;Yu Yanlan;Zhang Yuanyuan;He Lli;Qiu Linli;Zhao Jikai;Liu Mengying;Zhang Jiqiang
5 雌激素β受体对小鼠海马actin聚合调节蛋白表达的影响及其机制 期刊论文 何丽;赵焱钢;邱林利;张媛媛;赵继凯;邢方舟;张吉强;李巍
6 Hippocampus-specific Rictor knockdown inhibited 17beta-estradiol induced neuronal plasticity and spatial memory improvement in ovariectomized mice. 期刊论文 Sun Tao;Liu Zhi;Liu Mengying;Guo Ying;Sun Huan;Zhao Jikai;Lan Zhen;Lian Biyao;Zhang Jiqiang
7 GPR30-mediated estrogenic regulation of actin polymerization and spatial memory involves SRC-1 and PI3K-mTORC2 in the hippocampus of female mice. 期刊论文 Zhang Yuan Yuan;Liu Meng Ying;Liu Zhi;Zhao Ji Kai;Zhao Yan Gang;He Li;Li Wei;Zhang Ji Qiang
8 Letrozole induces worse hippocampal synaptic and dendritic changes and spatial memory impairment than ovariectomy in adult female mice. 期刊论文 Liu Mengying;Xing Fangzhou;Bian Chen;Zhao Yangang;Zhao Jikai;Liu Yan;Zhang Jiqiang
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